NIVEA UV Deep Protect & Care Gel for acne-prone skin

How to apply

Questions and answers

What the research says

• Replacing 20% of the chemical UV filter octyl methoxycinnamate with urucum oil in solid lipid nanoparticles maintained the skin protection factor without inducing toxic responses or significant skin penetration in human volunteers.

  Skin Pharmacology and Physiology, 2018

• Liposomal encapsulation of octyl methoxycinnamate increases its safety, skin affinity, and in vivo solar photoprotection factor while slowing its release and enhancing retention in the stratum corneum compared to a conventional formulation.

  International Journal of Nanomedicine, 2013

• Encapsulation of ethylhexyl methoxycinnamate and butyl methoxydibenzoylmethane in lipid microparticles significantly reduced their in vivo human skin penetration compared to nonencapsulated filters.

  Skin Pharmacology and Physiology, 2011

• Oral and dermal administration of Uvinul A plus resulted in three major urinary metabolites accounting for 52% of the oral dose, with a very low estimated daily systemic exposure of 8.1-9.3 μg/d in volunteers not intentionally exposed.

  International Journal of Hygiene and Environmental Health, 2020

• Maximal topical applications of 6% bemotrizinol in a model sunscreen formulation did not result in meaningful systemic exposure in humans.

  Regulatory Toxicology and Pharmacology, 2023

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Lonicera japonica and Citri Reticulatae Pericarpium Polyphenolic Extract (LCPE) reduces inflammation-mediating cytokines COX-2 and iNOS and inhibits NF-kB and MAPK pathways in lipopolysaccharide-induced skin keratinocytes.

  Antioxidants, 2023

• The incorporation of blue honeysuckle powder into cosmetic face masks resulted in stable emulsions that provided proper skin hydration and altered the physical properties of the masks.

  Molecules, 2021

Ingredients

Water, Alcohol, Ethylhexyl Methoxycinnamate, Butylene Glycol, Caprylyl Methicone, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Isopropyl Palmitate, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Diisopropyl Sebacate, Ethylhexyl Triazone, Polysilicone-15, Silica Dimethyl Silylate, Lonicera Japonica Flower Extract Honeysuckle Flower Extract, Hydrolyzed Conchiolin Protein, Polianthes Tuberosa Polysaccharide, Rosa Damascena Flower Water, Sodium Hyaluronate, Pyrus Cydonia Seed Extract, Polymethylsilsesquioxane, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Lauroyl Lysine, Hydroxypropyl Methylcellulose Stearoxy Ether, Sodium Dilauramidoglutamide Lysine, C30-45 Alkyl Methicone, C30-45 Olefin, Menthoxypropanediol, Phenoxyethanol, Sodium Hydroxide, Bht, Methylparaben

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.