Paula's Choice Pro-Collagen Multi-Peptide Booster for dry skin
6x Peptide Complex
Sodium Hyaluronate
Hydrolyzed Yeast Extract
Pyrus Malus Fruit Extract
Palmitoyl Tripeptide-5
Superior
- SuperiorDry Skin Fit
- HighEffectiveness
- ExcellentSafety
One of the best serums for dry skin.
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Excellent suitability for your dry skin is provided by humectants like Glycerin and Sodium Hyaluronate, which deeply hydrate and support barrier function, complemented by peptides such as Palmitoyl Tripeptide-5 and Sh-Polypeptide-121 that promote skin firming and plumping.
- The inclusion of Glycolic Acid and Polygonum Bistorta Root Extract further enhances skin texture and radiance, addressing your goal of reducing dryness and flakiness.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.
How to apply
- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
People Say
★4.5Overall rating based on 600+ reviewsUsers report this lightweight gel booster provides immediate plumping and hydration, often improving skin texture and softening fine lines overnight. While it is highly effective for firming and layering, a moderate number of users found the scent and price to be drawbacks, and a low number experienced breakouts or redness.
Highlights
Plumps and firms Mostly Mentioned
- “skin looks plumper”
- “immediate firming benefit”
- “complexion look bouncier”
- “felt skin plumping up”
Hydrates and glows Often Mentioned
- “instantly hydrates”
- “gives a nice glow”
- “leaves skin supple”
- “soft and smooth”
Lightweight texture Often Mentioned
- “melts into skin effortlessly”
- “lightweight gel formula”
- “layers seamlessly”
- “absorbs instantly”
Expensive for size Often Mentioned
- “price is astronomical”
- “bottle size is smaller”
- “bit pricey”
- “doesn't last long”
Smooths lines Sometimes Noted
- “wrinkle on forehead softened”
- “makeup no longer creases”
- “lines appear smoother”
- “blur lines”
Messy packaging Sometimes Noted
- “dropper can be unpredictable”
- “release far more than desired”
- “messy”
- “hard to control”
Unpleasant scent Sometimes Noted
- “smell like a mildewy rag”
- “unpleasant mop-like odor”
- “made me gag”
- “scent is off-putting”
Caused breakouts Rarely Noted
- “caused redness in cheek”
- “break out very badly”
- “closed comedones”
- “not for sensitive skin”
Sources: lovi.care, paulaschoice.com, sephora.com, dermstore.com, skincarma.com, youtube.com, and more
Questions and answers
What makes Paula's Choice Pro-Collagen Multi-Peptide Booster one of the best fits for dry skin?
This booster is an exceptional fit for dry skin because it uses hydrating ingredients like glycerin and sodium hyaluronate to deeply quench and protect the skin barrier, while peptides help firm and plump. It also features apple fruit extract and other plant extracts to improve texture and smooth away flakiness without any risk of irritation.
Which ingredients make this booster a good fit for dry skin?
This booster is an exceptional fit for dry skin because ingredients like glycerin and sodium hyaluronate deeply hydrate and support your moisture barrier, while peptides firm and plump. Additionally, apple fruit extract and other plant extracts help smooth away dryness and flakiness without causing irritation.
What does Peptide Complex do for dry skin?
Peptide Complex helps keep dry skin hydrated and smooth. Studies show that peptide supplements can increase skin water content, improve elasticity, and help maintain a healthy moisture barrier.
Skin Pharmacology and Physiology, 2021Journal of Microbiology and Biotechnology, 2025
What does Hyaluronic Acid do for dry skin?
Hyaluronic acid draws moisture into dry skin, giving an immediate and lasting boost in hydration that helps smooth out fine lines and soften rough patches. It is very gentle and unlikely to cause irritation while improving overall skin smoothness and plumpness.
Dermatology and Therapy, 2021Journal of Drugs in Dermatology, 2011
Where does this booster go in a skincare routine for dry skin?
This booster goes in the evening routine after cleansing and before your moisturizer. Using it at this step helps keep things simple and protects your skin around sun exposure.
Can I use this booster with retinol, and in what order?
Yes, you can use this booster with retinol by applying the booster first to deeply hydrate your dry skin and smooth its texture, followed by your retinol. This product is very gentle and unlikely to cause irritation, making it a supportive pairing for an active routine.
Clinical, Cosmetic and Investigational Dermatology, 2017Dermatologic Therapy, 2022
How often should I use this booster?
This booster works well in your evening routine, and some people may also use it in the morning or twice a day. The gentle ingredients provide an excellent safety profile with very low risk of irritation for dry skin.
Can this booster clog pores, cause breakouts or purging for dry skin?
This booster is unlikely to clog pores or cause breakouts on dry skin, as it has an excellent safety profile with soothing ingredients and no harsh components. Reviewers rarely report breakouts from using it.
Is this booster fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.
Dermatologic Therapy, 2022A cosmetic cream with 6% standardized wild apple fruit extract and a conventional emulsifier demonstrated stable antioxidant activity of 19.25 %RSC, increased skin moisturization, and a decreased melanin index by -31.40 without causing skin irritation.
International Journal of Cosmetic Science, 2019Dermocosmetic creams containing 6%, 12%, and 15% of standardized wild apple fruit ultrasonic extract increased skin hydration proportionally to extract concentration after 28 days of application on healthy volunteers without altering transepidermal water loss or skin pH.
Journal of Cosmetic Dermatology, 2022Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical moisturizers improved skin barrier function and surface moisture, while a postbiotic moisturizer with yeast extract uniquely supported microbiome balance and modulated biomarkers of skin barrier, structure, and inflammation in participants and ex vivo explants exposed to environmental aggressors.
Journal of Clinical Medicine, 2023A maintenance therapy with a cosmeceutical formulation containing hydroxyphenoxy propionic acid, ellagic acid, yeast extract, and salicylic acid over 20 weeks significantly improved even skin tone, spot intensity, spot size, and overall hyperpigmentation in 33 healthy subjects with moderate facial dyspigmentation.
Journal of Drugs in Dermatology, 2015A methanol yeast extract increases proliferation and migration while decreasing entrance into senescence and apoptosis phases in 3T3 fibroblast cells.
Journal of Cosmetic Science, 2014Topical formulations containing 1.25% Malus sp. extract or 0.75% rutin protected against UVB-induced sunburn cells, caspase-3 activation, cyclobutane pyrimidine dimers, lipid peroxidation, and metalloproteinase formation in ex vivo skin explants and 3D tissue-engineered skin.
Rejuvenation Research, 2020Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects.
Colloids and Surfaces. B, Biointerfaces, 2025
Ingredients
Water, Glycerin, Pentylene Glycol, Hydrolyzed Yeast Extract, Pyrus Malus Fruit Extract, Dimethicone, Propanediol, 1,2-Hexanediol, Glyceryl Glucoside, Palmitoyl Tripeptide-72 Amide, Sh-Polypeptide-121, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-5, Tridecapeptide-1, Polyglucuronic Acid, Sodium Hyaluronate, C9-12 Alkane, Ammonium Polyacryloyldimethyl Taurate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Polygonum Bistorta Root Extract, Bacillus Ferment, Lecithin, Sodium Phytate, Coco-Caprylate Caprate, Hexylene Glycol, Cetyl Hydroxyethylcellulose, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Magnesium Chloride, Potassium Sorbate, Sodium Benzoate
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-
Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-
Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-
Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-
Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-
Medical Board
Cosmetic chemist, SCS, IFSCC member
-
Medical Board, Medical Advisor
Dermatology MD
-
Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-
Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.