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Lactic acid and hexapeptide-9

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Lactic acid and hexapeptide-9: keep them apart

Keep them apart

Use them at different times of day by applying lactic acid in the morning and hexapeptide-9 at night, because acid ruins the peptide. The acid is too strong for the peptide and breaks it down, so your skin misses out on the anti-aging benefits. You can fix this by using them in separate routines or waiting longer between steps.

Lactic acid products

Hexapeptide-9 products

Questions and answers

Can you use lactic acid and hexapeptide-9 together?

Keep lactic acid and hexapeptide-9 apart in your routine because the low pH of the acid may destabilize the peptide bonds and reduce its effectiveness. Instead, use them in separate steps or routines, such as applying one in the morning and the other at night.

Which goes first, lactic acid or hexapeptide-9?

Keep lactic acid and hexapeptide-9 separate by using them in different routines, such as applying one in the morning and the other at night, because the low pH of lactic acid can destabilize hexapeptide-9 and reduce its effectiveness.

Are lactic acid and hexapeptide-9 good for sensitive skin?

Lactic acid and hexapeptide-9 should be kept apart to protect sensitive skin. The low pH of lactic acid destabilizes peptide bonds and may reduce the bioactivity of hexapeptide-9 when used in the same routine.

Research on lactic acid and hexapeptide-9

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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