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Hexapeptide and lactic acid

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Hexapeptide and lactic acid: keep them apart

Keep them apart

Apply lactic acid and hexapeptide at different times of day because acids break down peptides and ruin their anti-aging power. The acidic lactic acid destroys the delicate structure of the hexapeptide, stopping it from smoothing your skin. You can use one in the morning and the other at night, or use milder formulas.

Hexapeptide products

Lactic acid products

Questions and answers

Can you use hexapeptide and lactic acid together?

No, keep hexapeptide and lactic acid apart in your routine because the low pH of lactic acid may break down the peptide bonds and reduce its effectiveness. Instead, use them in separate steps or routines, such as applying one in the morning and the other at night.

Which goes first, hexapeptide or lactic acid?

Keep hexapeptide and lactic acid apart by using them in separate steps or routines, such as AM and PM separation. The low pH of lactic acid may destabilize the peptide bonds and reduce the bioactivity of hexapeptide.

Are hexapeptide and lactic acid good for sensitive skin?

Hexapeptide and lactic acid should be separated into different routines to protect sensitive skin because the low pH of lactic acid may destabilize peptides and reduce their effectiveness.

Research on hexapeptide and lactic acid

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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