Some By Mi Yuja Niacin Brightening All-In-One Cleanser for sensitive skin

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Questions and answers

What the research says

• Concurrent treatment with 3-O-ethyl ascorbic acid and cannabigerol in UVB-irradiated human keratinocytes prevents membrane structure alterations, promotes cell survival, enhances antioxidant enzyme activity and GSH- and Trx-dependent systems, reduces lipid and protein oxidative modifications, and exerts anti-inflammatory effects.

  Free Radical Biology & Medicine, 2025

• Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.

  The British Journal of Dermatology, 2002

• A multi-component dissolving microneedle patch loaded with glabridin, 3-O-ethyl-L-ascorbic acid, and tranexamic acid effectively reduced chloasma and age spots while demonstrating safety in clinical evaluation, alongside significant antioxidant, anti-tyrosinase, and melanin-reduction effects in vitro and in vivo.

  Polymers, 2023

• Citrus junos callus extract decreased melanin content in melanocytes 1.85-fold compared with arbutin and promoted the proliferation of and procollagen synthesis by human fibroblasts by 154% and 176% at 500 μg/mL.

  Molecules, 2017

• Yuja-peel fractions (ethyl acetate, hexane, and butanol) inhibited MMP expression, induced moisturizing factors filaggrin and serine palmitoyltransferase, and decreased melanin content in UVB-irradiated HaCaT, HDF, and α-MSH-treated B16F10 cells.

  Antioxidants, 2022

• Upcycled low-molecular-weight anionic peptides from Citrus junos seeds protected UVR-irradiated keratinocytes and reconstructed skin tissue by scavenging reactive oxygen species, reducing paracrine cytokines, inhibiting melanin synthesis and TRP-2 expression, and increasing filaggrin, laminin-5, and type I collagen expression.

  International Journal of Molecular Sciences, 2024

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.

  Experimental Dermatology, 2003

• Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.

  Journal of Periodontology, 2009

• Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.

  Journal of Cosmetic Dermatology, 2022

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

Ingredients

Water, Sodium C14-16 Olefin Sulfonate, Citrus Junos Fruit Extract, Cocamidopropyl Betaine, Acrylates Copolymer, 1,2-Hexanediol, Gluconolactone, Tetradecene, Sodium Chloride, Glycerin, Hexadecene, Saccharide Isomerate, Caprylyl Glycol, Xanthan Gum, Sodium Citrate, Citric Acid, Niacinamide, Propanediol, Sodium Hyaluronate, 3-O-Ethyl Ascorbic Acid, Succinic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Eriobotrya Japonica Leaf Extract, Hydrogenated Lecithin, Hydrolyzed Glycosaminoglycans, Polyglyceryl-10 Stearate, Panthenol, Spearmint Extract, Sodium Acetylated Hyaluronate, Benzyl Glycol, Sodium Ascorbyl Phosphate, Ethylhexylglycerin, Biotin, Pyridoxine, Folic Acid, Raspberry Ketone, Tocopherol, Cyanocobalamin, Linoleic Acid, Thiamine Hcl, Inositol, Riboflavin, Beta-Carotene, Disodium Edta, Limonene, Linalool

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.