Estée Lauder Advanced Night Repair Eye Supercharged Gel-Creme for skin with dark spots

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.

  Journal of Cosmetic Dermatology, 2023

• Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine.

  Journal of Pharmacy & Pharmaceutical Sciences, 2015

• A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.

  Journal of Cosmetic Dermatology, 2020

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• A topical cosmetic slimming product containing tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol significantly reduced body circumferences and improved skin aspect compared with placebo in 78 women over 12 weeks.

  International Journal of Cosmetic Science, 2011

• Topical sunscreen formulations containing caffeine combined with UV filters increased in vivo anti-UVB protection by approximately 25% and showed higher SPF values compared to caffeine-free sunscreen, while being well tolerated by the skin of healthy subjects.

  Frontiers in Physiology, 2019

• Caffeine gel combined with choline geranate showed high skin permeation capacity and superior clinical results in cellulite treatment compared to caffeine gel without ionic liquid.

  AAPS PharmSciTech, 2021

• Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

  Molecules, 2025

• Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

  Antioxidants, 2025

Why other eye cares fit skin with dark spots better

• An antipollution, antioxidant serum containing Deschampsia antarctica extract, ferulic acid, and vitamin C reduced transepidermal water loss by 19%, improved dark spots by 7%, and decreased the squalene peroxide to squalene ratio by 16% compared to baseline in twenty women living in a high air pollution area over 28 days.

  Clinical, Cosmetic and Investigational Dermatology, 2019

• Topical application of a water-in-oil emulsion containing 2% Muscat hamburg grape seed extract significantly improved melanin, elasticity, and sebum content compared to a placebo in human volunteers over 8 weeks, with no reported skin hypersensitivity.

  International Journal of Cosmetic Science, 2015

• Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.

  The British Journal of Dermatology, 2002

Ingredients

Water, Dimethicone, Methyl Trimethicone, Bifida Lysate Ferment, Dimethicone Vinyl Dimethicone Crosspolymer, Propanediol, Petrolatum, Sucrose, Glycerin, Butylene Glycol, Acrylamide Sodium Acryloyldimethyltaurate Copolymer, Trehalose, Tripeptide-32, Adansonia Digitata Seed Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Sodium Hyaluronate, Lactobacillus Ferment, Tocopheryl Acetate, Yeast Extract, Hypnea Musciformis Extract, Sodium Rna, Caffeine, Squalane, Anthemis Nobilis Oil Flower, Poria Cocos Sclerotium Extract, Watermelon Fruit Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Ethylhexylglycerin, Sodium Pca, Phytosphingosine, Hydrolyzed Algin, Hordeum Distichon Extract Hordeum Vulgare Extract, Jojoba Esters, Wheat Germ Oil, Hydrogenated Lecithin, Lecithin, Isohexadecane, Jojoba Alcohol, Isopropyl Jojobate, Peg Ppg-18 18 Dimethicone, Polysorbate 80, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Sorbitan Oleate, Sodium Lactate, Polysorbate 40, Potassium Gluconate, Tocopherol, Bht, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate, Iron Oxides Ci 77491, Iron Oxides Ci 77492

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.