CLEARSTEM skincare

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

CLEARSTEM is an American skincare brand founded in 2017.

CLEARSTEM is loved for its luxurious moisturizers and serums, featuring carefully developed formulas that nourish the skin. Its products suit acne-prone skin best, as well as complexions dealing with uneven tone. For targeted care, the standout products include the HYDRAGLOW Moisturizer for acne-prone skin and the CELLRENEW Serum for skin with dark spots. The brand delivers dependable results through balanced daily applications.

This page covers some of the most popular CLEARSTEM products; for the whole CLEARSTEM range, with a fit score for every product, use the Lovi app.

Other CLEARSTEM products

Questions and answers

Is CLEARSTEM worth it?

CLEARSTEM is worth considering because Lovi rates its brand-focused routines Superior for dry, oily, sensitive, combination, and acne-prone skin. Every product from CLEARSTEM on this page is also fragrance-free.

What are CLEARSTEM's best products?

CLEARSTEM offers HYDRAGLOW Moisturizer and CELLRENEW Serum on this page. Lovi rates the CLEARSTEM-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin.

Which CLEARSTEM moisturizer is best for dry skin?

HYDRAGLOW Moisturizer is the best choice among the moisturizers on this page for dry skin, where Lovi rates it Average. It helps keep the skin soft and nourished.

Dermatologic Therapy, 2022

Does CLEARSTEM cause breakouts?

CLEARSTEM is unlikely to cause breakouts because its products on this page are designed to be friendly to acne-prone skin. Lovi rates the CLEARSTEM-focused routine Superior for acne-prone skin.

Is CLEARSTEM fragrance-free?

Yes, every product from the CLEARSTEM products on this page lists no fragrance in its ingredients, making them free of added scent.

What are the key ingredients in CLEARSTEM products?

CLEARSTEM uses ingredients such as green tea extract, hyaluronic acid, bakuchiol, and panthenol across its formulas. These components help soothe the skin, provide moisture, and improve the look of aging.

Carcinogenesis, 2001 Dermatologic Therapy, 2022

How do I build a CLEARSTEM skincare routine?

To build a CLEARSTEM routine, apply the CELLRENEW Serum and follow it with the HYDRAGLOW Moisturizer. Lovi rates the CLEARSTEM-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin.

What are good alternatives to CLEARSTEM?

Good alternatives to CLEARSTEM include CeraVe, Cetaphil, Paula's Choice, Neutrogena, Kiehl's, and Dermalogica. These brands also offer skincare routines and products that may suit various skin types.

CLEARSTEM vs CeraVe: which is better?

CLEARSTEM and CeraVe both perform at the highest level, with Lovi rating the CLEARSTEM-focused and CeraVe-focused routines as Superior for dry, oily, sensitive, combination, and acne-prone skin.

Is CLEARSTEM cruelty-free?

PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list CLEARSTEM as cruelty-free.

5 more questions

Research behind CLEARSTEM's key ingredients

Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage
Antioxidants · Drug Delivery, 2017
Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress
Camellia sinensis extract, Camellia sinensis · Carcinogenesis, 2001
Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence
Sodium hyaluronate · Dermatologic Therapy, 2022
Topical use of dexpanthenol in skin disorders
Panthenol b5 · American Journal of Clinical Dermatology, 2002
Cutaneous photoprotection from ultraviolet injury by green tea polyphenols
Camellia sinensis extract · Journal of the American Academy of Dermatology, 2001

13 more studies

Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes
Camellia sinensis · The Journal of Investigative Dermatology, 2013
Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing
Bakuchiol · The British Journal of Dermatology, 2019
Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Squalane · Scientific Reports, 2020
Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations
Aloe barbadensis leaf extract, Aloe barbadensis · Clinical Pharmacology, 2018
A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin
Camellia sinensis · The Journal of Investigative Dermatology, 2019
The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study
Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
Safety and Toxicological Evaluation of a Novel, Standardized 3-O-Acetyl-11-keto-beta-Boswellic Acid (AKBA)-Enriched Boswellia serrata Extract (5-Loxin(R))
Boswellia carterii oil · Toxicology Mechanisms and Methods, 2006
A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora
Panthenol b5 · The Journal of Dermatological Treatment, 2017
Randomized, placebo-controlled, double blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoageing of facial skin
Alpha lipoic acid · The British Journal of Dermatology, 2003
A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial
Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
Assessment of cubosomal alpha lipoic acid gel efficacy for the aging face: a single-blinded, placebo-controlled, right-left comparative clinical study
Alpha lipoic acid · Journal of Cosmetic Dermatology, 2017
Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study
Panthenol b5 · Journal of Cosmetic Dermatology, 2025
Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population
Bakuchiol · Health Science Reports, 2025

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Behind these ratings

Lovi rates every product from its full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

Nadia Kapleva, MS

Co-founder, Medical Director

Cosmetic chemist, cosmetologist, aesthetic products developer
Alexey Shagraev, PhD

Co-founder, CEO and CTO

PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
Dr. Sofía Perea Pérez, MD, MSc

Medical Board

Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
Aishani Shah, MD

Medical Board

Specialist dermatologist, MBBS, MD, IFAAD
Asya Zubkova, MS

Medical Board

Cosmetic chemist, SCS, IFSCC member
Hanna Kurets, MD

Medical Board, Medical Advisor

Dermatology MD
Elina Nazarenko, MD

Medical Board

Dermatology and diagnostic consultant
Victoria Derkova, MS

Medical Board

Cosmetic chemist, cosmetic development technologist