CLEARSTEM skincare

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

CLEARSTEM is an American skincare brand founded in 2017.

CLEARSTEM is loved for its luxurious moisturizers and serums, featuring carefully developed formulas that nourish the skin. Its products suit acne-prone skin best, as well as complexions dealing with uneven tone. For targeted care, the standout products include the HYDRAGLOW Moisturizer for acne-prone skin and the CELLRENEW Serum for skin with dark spots. The brand delivers dependable results through balanced daily applications.

This page covers some of the most popular CLEARSTEM products; for the whole CLEARSTEM range, with a fit score for every product, use the Lovi app.

Other CLEARSTEM products

Questions and answers

Is CLEARSTEM worth it?

Yes, CLEARSTEM is worth it, as Lovi rates the CLEARSTEM-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin. The CLEARSTEM products on this page also list no fragrance in their ingredients.

What are CLEARSTEM's best products?

CLEARSTEM's best-performing products on this page are HYDRAGLOW Moisturizer and CELLRENEW Serum, both of which achieve high fit ratings across several skin types such as dry, mature, and sensitive skin. Lovi rates the CLEARSTEM-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin.

Which CLEARSTEM moisturizer is best for dry skin?

HYDRAGLOW Moisturizer is the moisturizer on this page for dry skin. Lovi rates HYDRAGLOW Moisturizer Average for dry skin.

Does CLEARSTEM cause breakouts?

CLEARSTEM is unlikely to cause breakouts because its formulas are designed to be non-clogging. Lovi rates oily acne-prone skin and acne-prone skin High for HYDRAGLOW Moisturizer and Average for CELLRENEW Serum.

Is CLEARSTEM fragrance-free?

Yes, every one of the CLEARSTEM products on this page lists no fragrance in its ingredients.

What are the key ingredients in CLEARSTEM products?

The key ingredients in the CLEARSTEM products on this page include green tea extract, hyaluronic acid, bakuchiol, and squalane. These components help keep skin soft and smooth while protecting it from everyday damage.

Carcinogenesis, 2001 Dermatologic Therapy, 2022

How do I build a CLEARSTEM skincare routine?

To build a CLEARSTEM routine, apply the CELLRENEW Serum and follow with the HYDRAGLOW Moisturizer. Lovi rates the CLEARSTEM-focused routine Superior for dry skin, oily skin, sensitive skin, combination skin, and acne-prone skin.

What are good alternatives to CLEARSTEM?

Good alternatives to CLEARSTEM with pages on Lovi include CeraVe, Cetaphil, Paula's Choice, Neutrogena, Kiehl's, and Dermalogica.

CLEARSTEM vs CeraVe: which is better?

CLEARSTEM routines are better for dry, oily, sensitive, combination, and acne-prone skin, as Lovi rates CLEARSTEM as Superior for all these skin types while CeraVe is rated High or Superior.

Is CLEARSTEM cruelty-free?

PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list CLEARSTEM as cruelty-free.

5 more questions

Research behind CLEARSTEM's key ingredients

Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage
Antioxidants · Drug Delivery, 2017
Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress
Camellia sinensis extract, Camellia sinensis · Carcinogenesis, 2001
Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence
Sodium hyaluronate · Dermatologic Therapy, 2022
Topical use of dexpanthenol in skin disorders
Panthenol b5 · American Journal of Clinical Dermatology, 2002
Cutaneous photoprotection from ultraviolet injury by green tea polyphenols
Camellia sinensis extract · Journal of the American Academy of Dermatology, 2001

13 more studies

Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes
Camellia sinensis · The Journal of Investigative Dermatology, 2013
Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing
Bakuchiol · The British Journal of Dermatology, 2019
Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Squalane · Scientific Reports, 2020
Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations
Aloe barbadensis leaf extract, Aloe barbadensis · Clinical Pharmacology, 2018
A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin
Camellia sinensis · The Journal of Investigative Dermatology, 2019
The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study
Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
Safety and Toxicological Evaluation of a Novel, Standardized 3-O-Acetyl-11-keto-beta-Boswellic Acid (AKBA)-Enriched Boswellia serrata Extract (5-Loxin(R))
Boswellia carterii oil · Toxicology Mechanisms and Methods, 2006
A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora
Panthenol b5 · The Journal of Dermatological Treatment, 2017
Randomized, placebo-controlled, double blind study on the clinical efficacy of a cream containing 5% alpha-lipoic acid related to photoageing of facial skin
Alpha lipoic acid · The British Journal of Dermatology, 2003
A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial
Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
Assessment of cubosomal alpha lipoic acid gel efficacy for the aging face: a single-blinded, placebo-controlled, right-left comparative clinical study
Alpha lipoic acid · Journal of Cosmetic Dermatology, 2017
Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study
Panthenol b5 · Journal of Cosmetic Dermatology, 2025
Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population
Bakuchiol · Health Science Reports, 2025

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Behind these ratings

Lovi rates every product from its full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

Nadia Kapleva, MS

Co-founder, Medical Director

Cosmetic chemist, cosmetologist, aesthetic products developer
Alexey Shagraev, PhD

Co-founder, CEO and CTO

PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
Dr. Sofía Perea Pérez, MD, MSc

Medical Board

Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
Aishani Shah, MD

Medical Board

Specialist dermatologist, MBBS, MD, IFAAD
Asya Zubkova, MS

Medical Board

Cosmetic chemist, SCS, IFSCC member
Hanna Kurets, MD

Medical Board, Medical Advisor

Dermatology MD
Elina Nazarenko, MD

Medical Board

Dermatology and diagnostic consultant
Victoria Derkova, MS

Medical Board

Cosmetic chemist, cosmetic development technologist