Avène Cleanance Comedoned Peeling for combination skin
Glycolic Acid
Salicylic Acid
Zinc GluconateAverage
- HighCombination Skin Fit
- AverageEffectiveness
- HighSafety
Works for combination skin; other products fit it better.
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate exfoliation for your combination skin, as glycolic acid and salicylic acid work to address oily shine and provide general skincare benefits.
- The keratolytic action and seboregulation from these acids make it highly suitable for your skin type, though the concentrations offer general benefits rather than targeted treatment.
- The formulation is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use this exfoliant product in your PM routine starting once a week, then increase frequency carefully if your skin feels fine.
- Apply this exfoliant step after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the exfoliant into your skin and wait a minute before layering.
- Apply the exfoliant to clean, dry skin to help control your oily shine comfortably.
- Avoid the eye area and do a patch test before your first use.
People Say
★4.6Overall rating based on 100+ reviewsThis spot treatment is highly effective for reducing active breakouts and improving skin texture on acne-prone skin, with many users reporting rapid results. While generally well-tolerated, a strong alcohol scent is frequently noted, and some users experience mild irritation or find the usage instructions confusing. The product is praised for its lightweight, fast-absorbing texture.
Highlights
Rapid effectiveness Mostly Mentioned
- “results in just a few days”
- “pimples disintegrated overnight”
- “significantly improves blemishes in one day”
- “calmed my blemishes immediately”
Excellent texture Often Mentioned
- “absorbs super fast”
- “non-greasy finish”
- “lightweight texture”
- “no sticky after-feel”
- “penetrates instantly”
Strong alcohol scent Often Mentioned
- “powerful alcohol smell”
- “smells like hand sanitizer”
- “scent is strong”
- “lingering scent”
Good tolerance Sometimes Noted
- “no skin irritation”
- “did not clog pores”
- “non-aggressive”
- “feels gentle on skin”
Smoother skin texture Sometimes Noted
- “smoother skin texture”
- “keeps pimples at bay”
- “skin looks clearer”
- “reduces comedones”
Confusing usage limits Sometimes Noted
- “instructions are confusing”
- “maximum duration of 15 days?”
- “unsure if safe for long term”
- “limit use to 15 days”
Potential irritation Rarely Noted
- “itching was persistent”
- “broke me out”
- “stinging sensation”
- “skin felt reactive”
Price vs. size Rarely Noted
- “small price to pay”
- “expensive for size”
- “tube is small”
Sources: lovi.care, cocooncenter.com, perfumesclub.co.uk, reddit.com, youtube.com, and more
Questions and answers
How well does Avène Cleanance Comedoned Peeling work for combination skin?
Avène Cleanance Comedoned Peeling works moderately well for your combination skin, using glycolic acid and salicylic acid to help address oily shine and provide general care safely. To achieve a better fit, a product of this type needs effective ingredients like niacinamide, propolis, or zinc PCA to provide optimal hydration, balance oiliness without dryness, and enhance radiance.
Journal of Cosmetic Dermatology, 2024Clinical, Cosmetic and Investigational Dermatology, 2023
Which ingredients make this exfoliant a good fit for combination skin?
Glycolic acid, salicylic acid, and zinc gluconate make this exfoliant a good fit for your combination skin by addressing oily shine and providing gentle exfoliation. To achieve an even better fit, combination skin needs products with effective ingredients like niacinamide, propolis, or zinc PCA that balance oiliness and maintain proper hydration without any risk of irritation.
What does Glycolic Acid do for combination skin?
Glycolic acid helps smooth and brighten combination skin by gently loosening dead surface cells to speed up skin renewal. This ingredient is unlikely to cause irritation when used properly, but it needs a reliable sunscreen during the day since it makes skin more sensitive to the sun.
Acta Dermato-venereologica, 1995Archives of Dermatological Research, 1997
What does Salicylic Acid do for combination skin?
Salicylic acid helps clear clogged pores and balance oily areas while remaining gentle enough for dry spots on combination skin. It reduces breakouts and oiliness effectively with a low likelihood of irritation.
Journal of Cosmetic Dermatology, 2024Journal of Drugs in Dermatology, 2023
Where does it go in a skincare routine for combination skin?
This treatment goes in the evening routine after cleansing and before moisturizing, starting once a week and using it more often if your skin tolerates it well. To work best for your combination skin, this type of product needs ingredients that gently clear away dead skin cells and control oil, like glycolic and salicylic acids.
Can I use this exfoliant with retinol, and in what order?
You can use this exfoliant with retinol by using them on different nights or spacing them out to keep your skin calm and smooth, since using both together may lead to dryness or irritation. To combine them safely, apply your retinol on certain nights and this treatment on others, always following up with a gentle moisturizer.
How often should I use it?
Start by using this exfoliant treatment once a week in your evening routine, and if your skin feels comfortable and you see good results, you may carefully use it more often. This product helps address oily shine on combination skin, though an ideal fit for this skin type would include targeted active ingredients and balanced concentrations for more personalized benefits.
Dermatologic Surgery, 2003Journal of Cosmetic Dermatology, 2021
Can this exfoliant clog pores, cause breakouts or purging for combination skin?
This exfoliant is unlikely to cause breakouts or clog pores on combination skin, as its ingredients help clear away dead skin and balance oil. A product for this skin needs gentle exfoliating acids and oil-balancing ingredients like salicylic acid and zinc gluconate to keep pores clear without causing irritation.
BioMed Research International, 2020Journal of Cosmetic Dermatology, 2024
Is it fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (parfum). Cetearyl alcohol is a fatty alcohol, which soften the skin.
What the research says
A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase.
BioMed Research International, 2020Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability.
Journal of Cosmetic Dermatology, 2024Daily use of a deep cleansing gel containing salicylic acid 2%, zinc gluconate 0.2% and lipohydroxy acid 0.05% significantly reduced total lesion count by 56.3% after 84 days in 35 subjects with mild to moderate truncal acne.
Clinical, Cosmetic and Investigational Dermatology, 2023Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks.
International Journal of Dermatology, 2000Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone.
Dermatologic Surgery, 2017Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients.
CMAJ, 2010Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy.
Journal of Cosmetic Dermatology, 2024Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients.
Journal of the American Academy of Dermatology, 2010A dermocosmetic cream containing Punica granatum Pericarp extract, Salicylic acid, Niacinamide, Zinc gluconate, and Aqua Posae Filiformis significantly decreased inflammatory, non-inflammatory, and total lesion counts in subjects with mild to moderate acne compared to untreated hemi-faces after 15 days.
Journal of Cosmetic Dermatology, 2026Different strains of Propionibacterium acnes modulate cutaneous innate immunity with varying pro-inflammatory potentials, with P. acnes type III showing the highest and P. avidum the weakest, and zinc gluconate down-regulates the expression of most induced immune markers.
Experimental Dermatology, 2013Zinc gluconate induced alpha2, alpha3, alphaV, and alpha6 integrins, copper gluconate induced alpha2, alpha6, and beta1, and manganese gluconate induced most studied integrins in cultured keratinocytes.
The British Journal of Dermatology, 1999
Ingredients
Water, Glycolic Acid, Glycerin, Cetearyl Alcohol, Sodium Hydroxide, Cetearyl Glucoside, Salicylic Acid, Zinc Gluconate, Pumpkin Seed Oil, Caprylic Capric Triglyceride, Benzoic Acid, Caprylyl Glycol, Parfum, Xanthan Gum, Disodium Edta, Citric Acid
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
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Specialist dermatologist, MBBS, MD, IFAAD
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Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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