Biotulin skincare

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Biotulin is a German skincare brand founded in 2014 and owned by Lorience Groupe since 2024.

beautymatter.com biotulin.com pitchbook.com

Skincare enthusiasts adore Biotulin for its targeted serums and meticulously crafted formulas that deliver a smoother, more refined appearance. Its products suit mature, dry, and sensitive skin best, offering gentle care without heavy or irritating additives. For acne-prone skin, the Supreme Skin Gel stands out as an effective choice to help balance and refine the complexion. Users appreciate how these gentle formulations work harmoniously to support a calm, healthy, and radiant look every day.

This page covers some of the most popular Biotulin products; for the whole Biotulin range, with a fit score for every product, use the Lovi app.

Biotulin serums and treatments

Supreme Skin Gel

Questions and answers

Is Biotulin worth it?

Biotulin is worth considering because Lovi rates the Biotulin-focused routines Superior for dry, oily, sensitive, combination, and acne-prone skin. Every product from the Biotulin products on this page is formulated without fragrance.

What are Biotulin's best products?

Supreme Skin Gel is the featured product for Biotulin on this page, and Lovi rates it High for sensitive skin and Average for dry, oily, and mature skin. The Biotulin products on this page list no fragrance in their ingredients.

Does Biotulin cause breakouts?

Biotulin is unlikely to cause breakouts. Supreme Skin Gel rates Average for oily and acne-prone skin, and the Biotulin-focused routine for acne-prone skin rates Superior on Lovi.

Is Biotulin fragrance-free?

Yes, every one of the Biotulin products on this page lists no fragrance in its ingredients.

What are the key ingredients in Biotulin products?

Biotulin products feature key ingredients like spilanthol, hyaluronic acid, and glycerin. Spilanthol helps smooth the skin by relaxing facial muscles, while hyaluronic acid and glycerin help keep the skin hydrated and soft.

International Journal of Cosmetic Science, 2021 Dermatologic Therapy, 2022

How do I build a Biotulin skincare routine?

To build a Biotulin routine, apply Supreme Skin Gel as your serum. Lovi rates the Biotulin-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin.

What are good alternatives to Biotulin?

Good alternatives to Biotulin include Eucerin, NIVEA, Bayer, Augustinus Bader, Yepoda, and Dr. Barbara Sturm, which also have pages on Lovi. Lovi rates the Eucerin-focused routine High for various skin types.

Biotulin vs Eucerin: which is better?

Biotulin is a better choice for dry, oily, sensitive, combination, and acne-prone skin, as Lovi rates the Biotulin-focused routine Superior for all of these skin types compared to the High rating for the Eucerin-focused routine.

Who owns Biotulin, and where is it from?

Biotulin is a German brand founded in 2014, owned by Lorience Groupe since 2024.

beautymatter.com biotulin.com pitchbook.com

Is Biotulin cruelty-free?

Yes: PETA lists Biotulin as cruelty-free.

PETA

Is Biotulin vegan?

Yes: PETA lists Biotulin as a vegan company.

PETA

6 more questions

Research behind Biotulin's key ingredients

Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence
Sodium hyaluronate · Dermatologic Therapy, 2022
The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study
Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
'All-natural' anti-wrinkle emulsion serum with Acmella oleracea extract: A design of experiments (DoE) formulation approach, rheology and in vivo skin performance/efficacy evaluation
Spilanthol · International Journal of Cosmetic Science, 2021
Preliminary safety and in vivo efficacy of Acmella oleracea extract-loaded glycolipid emulsion serum-Effects on ocular irritation, dermal absorption, and facial skin biophysical and microrelief properties
Spilanthol · International Journal of Cosmetic Science, 2025

Behind these ratings

Lovi rates every product from its full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

Nadia Kapleva, MS

Co-founder, Medical Director

Cosmetic chemist, cosmetologist, aesthetic products developer
Alexey Shagraev, PhD

Co-founder, CEO and CTO

PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
Dr. Sofía Perea Pérez, MD, MSc

Medical Board

Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
Aishani Shah, MD

Medical Board

Specialist dermatologist, MBBS, MD, IFAAD
Asya Zubkova, MS

Medical Board

Cosmetic chemist, SCS, IFSCC member
Hanna Kurets, MD

Medical Board, Medical Advisor

Dermatology MD
Elina Nazarenko, MD

Medical Board

Dermatology and diagnostic consultant
Victoria Derkova, MS

Medical Board

Cosmetic chemist, cosmetic development technologist