Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation
Niacinamide · Antioxidants, 2021Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress
Matcha green tea leaf extract camellia sinensis leaf extract, Camellia sinensis extract, Epigallocatechin gallate, Camellia sinensis · Carcinogenesis, 2001Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence
Curcuma longa root extract, Curcuma longa extract · Phytotherapy Research, 2016Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
Benzyl alcohol · International Journal of Toxicology, 2001Formation and stability of oil-in-water nanoemulsions containing rice bran oil: in vitro and in vivo assessments
Rice bran oil · Journal of Nanobiotechnology, 2011Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence
Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022Topical use of dexpanthenol in skin disorders
Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002Anti-inflammation activities of mycosporine-like amino acids (MAAs) in response to UV radiation suggest potential anti-skin aging activity
Amino acids · Marine Drugs, 2014The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review
Aloe barbadensis extract, Aloe barbadensis leaf juice, Aloe barbadensis leaf extract, Aloe barbadensis leaf juice powder, Aloe barbadensis leaf water · Iranian Journal of Medical Sciences, 2019Efficacy of combined treatment with human adipose tissue stem cell-derived exosome-containing solution and microneedling for facial skin aging: A 12-week prospective, randomized, split-face study
Exosome cica · Journal of Cosmetic Dermatology, 2023Bifidobacterium longum lysate, a new ingredient for reactive skin
1 · Experimental Dermatology, 2010Cutaneous photoprotection from ultraviolet injury by green tea polyphenols
Camellia sinensis extract · Journal of the American Academy of Dermatology, 2001Ganoderma lucidum polysaccharide inhibits UVB-induced melanogenesis by antagonizing cAMP/PKA and ROS/MAPK signaling pathways
Ganoderma lucidum extract · Journal of Cellular Physiology, 2019Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes
Matcha green tea leaf extract camellia sinensis leaf extract, Epigallocatechin gallate, Camellia sinensis · The Journal of Investigative Dermatology, 2013A systematic review of Calendula officinalis extract for wound healing
Calendula officinalis flower extract · Wound Repair and Regeneration, 2019Improvement of naturally aged skin with vitamin A (retinol)
Retinol · Archives of Dermatology, 2007Regulatory effects of Lactobacillus plantarum-GMNL6 on human skin health by improving skin microbiome
Probiotics · International Journal of Medical Sciences, 2021Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo
Ascorbyl palmitate ascorbic acid · Experimental Dermatology, 2003Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin
Aha alpha hydroxy acid · Journal of Dermatological Science, 2017Lactobacillus reuteri DSM 17938-A comparative study on the effect of probiotics and lysates on human skin
Probiotics · Experimental Dermatology, 2019Nicotinic acid/niacinamide and the skin
Niacin · Journal of Cosmetic Dermatology, 2004Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial
Ascorbic acid, Tocopherol, Tocopherol vitamin e · Journal of Cosmetic Dermatology, 2020A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation
Ferulic acid · Journal of the American Academy of Dermatology, 2008Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin
Ferulic acid · Journal of Cosmetic Dermatology, 2008The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study
Melaleuca alternifolia tree extract, Melaleuca alternifolia tree oil leaf, Melaleuca alternifolia tree leaf extract, Melaleuca alternifolia leaf extract, Melaleuca alternifolia oil leaf, 4-terpineol · Indian Journal of Dermatology, Venereology and Leprology, 2007Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics
Collagen · Dermatology Practical & Conceptual, 2022Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
Palmitoyl pentapeptide-4, Pentapeptide · International Journal of Cosmetic Science, 2005Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Retinol · International Journal of Cosmetic Science, 2017Combination of microneedling and glycolic acid peels for the treatment of acne scars in dark skin
Saccharum officinarum extract · Journal of Cosmetic Dermatology, 2011Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent
Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015Physiological effect of a probiotic on skin
Lactobacillus extract · Journal of Cosmetic Science, 2012The Effect of Lactobacillus plantarum Extracellular Vesicles from Korean Women in Their 20s on Skin Aging
Probiotics · Current Issues in Molecular Biology, 2022Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica
Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015Tea tree oil reduces histamine-induced skin inflammation
Melaleuca alternifolia tree leaf extract, Leaf extract tree, Tree · The British Journal of Dermatology, 2002Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Ascorbyl glucoside · Journal of Periodontology, 2009Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing
Retinol · The British Journal of Dermatology, 2019The estimation of the traditionally used yarrow (Achillea millefolium L. Asteraceae) oil extracts with anti-inflamatory potential in topical application
Achillea millefolium oil · Journal of Ethnopharmacology, 2017Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin
Scutellaria baicalensis root extract · Journal of Drugs in Dermatology, 2014Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin
Panax ginseng root extract, Panax ginseng water root · Journal of Ginseng Research, 2017Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women
Glutathione · Clinical, Cosmetic and Investigational Dermatology, 2014Lactate triggers KAT8-mediated LTBP1 lactylation at lysine 752 to promote skin rejuvenation by inducing collagen synthesis in fibroblasts
Lactic acid · International Journal of Biological Macromolecules, 2024Syringaresinol derived from Panax ginseng berry attenuates oxidative stress-induced skin aging via autophagy
Panax ginseng water root · Journal of Ginseng Research, 2022Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Chamomilla recutita flower extract matricaria flower extract, Chamomile extract, Chamomilla recutita flower extract, Chamomile, Chamomile flower extract, Chamomile extracts · International Journal of Molecular Medicine, 2016HelixComplex snail mucus as a potential technology against O3 induced skin damage
Black snail extract · PloS One, 2020A new role for the ginsenoside RG3 in antiaging via mitochondria function in ultraviolet-irradiated human dermal fibroblasts
Panax ginseng callus culture extract · Journal of Ginseng Research, 2019Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract
Centella asiatica extract, Madecassoside, Madecassic acid, Centella asiatica stem extract flower leaf, Asiaticoside, Centella asiatica leaf water, Centella asiatica · Indian Journal of Pharmaceutical Sciences, 2016Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling
Panax ginseng root extract · Journal of Ethnopharmacology, 2007Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy
Centella asiatica extract, Centella asiatica stem extract flower leaf, Centella asiatica leaf water, Centella asiatica · Pharmaceutics, 2024The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction
Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016Photoprotective Effects of a Hyperoside-Enriched Fraction Prepared from Houttuynia cordata Thunb. on Ultraviolet B-Induced Skin Aging in Human Fibroblasts through the MAPK Signaling Pathway
Houttuynia cordata extract, Heart leaf extract · Plants, 2021Papain Degrades Tight Junction Proteins of Human Keratinocytes In Vitro and Sensitizes C57BL/6 Mice via the Skin Independent of its Enzymatic Activity or TLR4 Activation
Carica papaya fruit extract · The Journal of Investigative Dermatology, 2015Tremella fuciformis polysaccharide suppresses hydrogen peroxide-triggered injury of human skin fibroblasts via upregulation of SIRT1
Tremella fuciformis · Molecular Medicine Reports, 2017Effect of fermentation time on the content of bioactive compounds with cosmetic and dermatological properties in Kombucha Yerba Mate extracts
Saccharomyces xylinum black tea ferment, Saccharomyces xylinum black tea · Scientific Reports, 2021Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Squalane · Scientific Reports, 2020Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations
Melaleuca alternifolia tree oil leaf, Aloe barbadensis leaf extract, Aloe barbadensis leaf juice, Melaleuca alternifolia tree leaf extract, Melaleuca alternifolia tree extract, Propolis extract, Aloe barbadensis extract, Melaleuca alternifolia leaf extract, Aloe barbadensis, Melaleuca alternifolia oil leaf, Aloe barbadensis leaf water, Aloe barbadensis leaf powder, Aloe barbadensis leaf juice powder, 4-terpineol · Clinical Pharmacology, 2018Topical Mannitol Reduces Capsaicin-Induced Pain: Results of a Pilot-Level, Double-Blind, Randomized Controlled Trial
Mannitol · PM & R, 2015Use of Collagen in Cosmetic Products
Collagen · Current Issues in Molecular Biology, 2024A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin
Matcha green tea leaf extract camellia sinensis leaf extract, Epigallocatechin gallate, Camellia sinensis · The Journal of Investigative Dermatology, 2019Urea: a comprehensive review of the clinical literature
Urea · Dermatology Online Journal, 2013Antioxidant properties evaluation of topical astaxanthin formulations as anti-aging products
Algae extract · Journal of Cosmetic Dermatology, 2019Moringa oleifera Leaf Extracts as Multifunctional Ingredients for "Natural and Organic" Sunscreens and Photoprotective Preparations
Moringa oleifera, Moringa oleifera leaf water · Molecules, 2018Effect of Camellia japonica oil on human type I procollagen production and skin barrier function
Camellia japonica flower extract · Journal of Ethnopharmacology, 2007Quorum quenching and antimicrobial activity of goldenseal (Hydrastis canadensis) against methicillin-resistant Staphylococcus aureus (MRSA)
Hydrastis canadensis extract · Planta Medica, 2012Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin
Ceramides, Sphingolipids · Scientific Reports, 2022Hyperoside and Quercitrin in Houttuynia cordata Extract Attenuate UVB-Induced Human Keratinocyte Cell Damage and Oxidative Stress via Modulation of MAPKs and Akt Signaling Pathway
Medicinal wheat extract, Heart leaf extract, Houttuynia cordata extract · Antioxidants, 2022Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin
Glyceryl glucoside · Skin Pharmacology and Physiology, 2012Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes
Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015Calendula extract: effects on mechanical parameters of human skin
Calendula officinalis flower · Acta Poloniae Pharmaceutica, 2011Preparation and characterization of a lecithin nanoemulsion as a topical delivery system
Hydroxylated lecithin · Nanoscale Research Letters, 2009Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study
Ascorbic acid · Clinical Oral Investigations, 2021Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin
Ceramide np · International Journal of Dermatology, 2008Effects of Locally Applied Glycerol and Xylitol on the Hydration, Barrier Function and Morphological Parameters of the Skin
Xylitylglucoside, Xylitol · Acta Dermato-venereologica, 2017Topical formulation containing hesperidin methyl chalcone inhibits skin oxidative stress and inflammation induced by ultraviolet B irradiation
Green tangerine extract · Photochemical & Photobiological Sciences, 2016Clinical efficacy comparison of anti-wrinkle cosmetics containing herbal flavonoids
Bioflavonoids · International Journal of Cosmetic Science, 2010Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation
Ferulic acid, Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020Antioxidant Artemisia princeps Extract Enhances the Expression of Filaggrin and Loricrin via the AHR/OVOL1 Pathway
Artemisia princeps leaf extract · International Journal of Molecular Sciences, 2017Assessment of extracts of Helichrysum arenarium, Crataegus monogyna, Sambucus nigra in photoprotective UVA and UVB; photostability in cosmetic emulsions
Crataegus monogina flower extract · Journal of Photochemistry and Photobiology. B, Biology, 2013Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo
Glycyrrhiza glabra root extract licorice root extract, Glycyrrhiza glabra root licorice root water root, Glycyrrhiza glabra leaf extract licorice leaf extract, Licorice root extract, Glycyrrhiza glabra root extract · Experimental Dermatology, 2015Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study
Retinyl palmitate · International Journal of Nanomedicine, 2021Injectable thermo-sensitive and wide-crack self-healing hydrogel loaded with antibacterial anti-inflammatory dipotassium glycyrrhizate for full-thickness skin wound repair
Dipotassium glycyrrhizate · Acta Biomaterialia, 2022Clinical Studies on Topical Curcumin
Curcuma longa root extract · Skin Pharmacology and Physiology, 2023Sambucus nigra L. ameliorates UVB-induced photoaging and inflammatory response in human skin keratinocytes
Sambucus nigra extract · Cytotechnology, 2019A double-blind, placebo-controlled randomized trial of Serratulae quinquefoliae folium, a new source of β-arbutin, in selected skin hyperpigmentations
Arbutin · Journal of Cosmetic Dermatology, 2015Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls
Camellia sinensis leaf extract · Experimental Dermatology, 2009Anti-inflammatory activities of colloidal oatmeal (Avena sativa) contribute to the effectiveness of oats in treatment of itch associated with dry, irritated skin
Avena sativa kernel extract oat kernel extract · Journal of Drugs in Dermatology, 2015Preparation and functional evaluation of collagen oligopeptide-rich hydrolysate from fish skin with the serine collagenolytic protease from Pseudoalteromonas sp. SM9913
Protease · Scientific Reports, 2017Systematic Study of Resveratrol Nanoliposomes Transdermal Delivery System for Enhancing Anti-Aging and Skin-Brightening Efficacy
Vitis vinifera juice grape juice, Resveratrol · Molecules, 2023Role of Resveratrol in Regulating Cutaneous Functions
Vitis vinifera juice grape juice · Evidence-based Complementary and Alternative Medicine, 2020Design, characterization, and clinical evaluation of argan oil nanostructured lipid carriers to improve skin hydration
Argania spinosa kernel oil · International Journal of Nanomedicine, 2014Ginsenoside Rk1 Prevents UVB Irradiation-Mediated Oxidative Stress, Inflammatory Response, and Collagen Degradation via the PI3K/AKT/NF-κB Pathway In Vitro and In Vivo
Panax ginseng callus culture extract · Journal of Agricultural and Food Chemistry, 2022Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin
Centella asiatica leaf extract · Experimental Dermatology, 2008Comparison of clinical and histological effects between lactobacillus-fermented Chamaecyparis obtusa and tea tree oil for the treatment of acne: an eight-week double-blind randomized controlled split-face study
Melaleuca alternifolia tree oil leaf, Melaleuca alternifolia oil leaf, 4-terpineol · Dermatology, 2014Quercetin loaded cosm-nutraceutical electrospun composite nanofibers for acne alleviation: Preparation, characterization and experimental clinical appraisal
Nelumbo nucifera flower extract · International Journal of Pharmaceutics, 2022A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin
Niacin · Experimental Dermatology, 2007The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study
Glycerin, Madecassoside, Madecassic acid · Clinical, Cosmetic and Investigational Dermatology, 2017The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial
Madecassoside, Madecassic acid, Asiaticoside, Centella asiatica leaf water · Journal of Alternative and Complementary Medicine, 2020Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy
Niacinamide · Journal of Cosmetic Dermatology, 2021Topical taurine bromamine, a new candidate in the treatment of moderate inflammatory acne vulgaris: a pilot study
Taurine · European Journal of Dermatology, 2008Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
Acetyl glucosamine · Journal of Cosmetic Dermatology, 2007Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial
Acetyl glucosamine · The British Journal of Dermatology, 2010Cytotoxicity of lecithin-based nanoemulsions on human skin cells and ex vivo skin permeation: Comparison to conventional surfactant types
Hydrogenated lecithin · International Journal of Pharmaceutics, 2019Resveratrol as a factor preventing skin aging and affecting its regeneration
Vitis vinifera juice grape juice · Postepy Dermatologii I Alergologii, 2022Next-Generation Wound Care: A Scoping Review on Probiotic, Prebiotic, Synbiotic, and Postbiotic Cutaneous Formulations
Probiotics · Pharmaceuticals, 2025Poly-L-Lactic acid increases collagen gene expression and synthesis in cultured dermal fibroblast (Hs68) through the TGF-β/Smad pathway
Lactic acid · Journal of Cosmetic Dermatology, 2023Synergism of plant extract and vegetable oils-based lipid nanocarriers: Emerging trends in development of advanced cosmetic prototype products
Daucus carota sativa seed oil carrot seed oil · Materials Science & Engineering. C, Materials for Biological Applications, 2020The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study
Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013Protective effects of Camellia japonica flower extract against urban air pollutants
Camellia japonica flower extract · BMC Complementary and Alternative Medicine, 2019Evaluation of dermatological effects of cosmetic formulations containing Saccharomyces cerevisiae extract and vitamins
Vinolevure · Food and Chemical Toxicology, 2008Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy
Oleanolic acid · Nanoscale Research Letters, 2020Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging
Montmorillonite · Carbohydrate Polymers, 2017Treatment of human skin with an extract of Fucus vesiculosus changes its thickness and mechanical properties
Algae extract · Journal of Cosmetic Science, 2002Effect of São Pedro do Sul thermal water on skin irritation
Water hungarian thermal water · International Journal of Cosmetic Science, 2010Camphor induces cold and warm sensations with increases in skin and muscle blood flow in human
Camphor oil bark · Biological & Pharmaceutical Bulletin, 2014Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging
Niacinamide · Scientific Reports, 2024A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora
Panthenol, Panthenol vitamin b5, Dexpanthenol · The Journal of Dermatological Treatment, 2017A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population
Salicylic acid, Microclear technology, Bha beta hydroxy acid · BioMed Research International, 2020Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin
Ascorbyl palmitate ascorbic acid · Antioxidants, 2024Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study
Glycolic acid, Saccharum officinarum extract · Journal of Cosmetic Dermatology, 2019Phytosphingosine enhances moisture level in human skin barrier through stimulation of the filaggrin biosynthesis and degradation leading to NMF formation
Moisturizing complex · Archives of Dermatological Research, 2017A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial
Melaleuca alternifolia tree oil leaf, Melaleuca alternifolia tree leaf extract, Melaleuca alternifolia tree extract, Melaleuca alternifolia leaf extract, Melaleuca alternifolia oil leaf, 4-terpineol · Archives of Dermatological Research, 2022Hydrolyzed Collagen Induces an Anti-Inflammatory Response That Induces Proliferation of Skin Fibroblast and Keratinocytes
Collagen extract · Nutrients, 2022Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration
Adenosine · International Journal of Cosmetic Science, 2018Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris
Mandelic acid · Journal of Cosmetic Dermatology, 2020Effects of lecithin-based nanoemulsions on skin: Short-time cytotoxicity MTT and BrdU studies, skin penetration of surfactants and additives and the delivery of curcumin
Hydrogenated lecithin · International Journal of Pharmaceutics, 2020Structural characterization and in vivo evaluation of retinyl palmitate in non-ionic lamellar liquid crystalline system
Retinyl palmitate · Colloids and Surfaces. B, Biointerfaces, 2011Efficacy of Green Tea Extract for Treatment of Dry Eye and Meibomian Gland Dysfunction; A Double-blind Randomized Controlled Clinical Trial Study
Camellia sinensis leaf extract · Journal of Clinical and Diagnostic Research, 2017Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide
Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012Alpha hydroxyacids modulate stratum corneum barrier function
Tartaric acid · The British Journal of Dermatology, 1997Hydroxypropyl methylcellulose hydrogel of berberine chloride-loaded escinosomes: Dermal absorption and biocompatibility
Enantia chlorantha bark extract · International Journal of Biological Macromolecules, 2020Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant
Caffeine · Frontiers in Physiology, 2019Exploring the Synergistic Effect of Bergamot Essential Oil with Spironolactone Loaded Nano-Phytosomes for Treatment of Acne Vulgaris: In Vitro Optimization, In Silico Studies, and Clinical Evaluation
Parfum · Pharmaceuticals, 2023Topical beta-carotene protects against infra-red-light-induced free radicals
Β-carotene · Experimental Dermatology, 2011High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin
Witch hazel extract, Witch hazel leaf water, Witch hazel extract bark twig leaf, Witch hazel water, Witch hazel, Witch hazel leaf extract, Witch hazel distillate, Hammelis virginiana witch hazel water · Phytochemistry, 2001The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study
Glycolic acid, Gluconolactone, Saccharum officinarum extract, Pha polyhydroxy acid · Clinical, Cosmetic and Investigational Dermatology, 2019Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial
Panthenol, Allantoin, Dexpanthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020Topical glutathione amino acid precursors protect skin against environmental and oxidative stress
Glutathione · Journal of the European Academy of Dermatology and Venereology, 2024Anti-melanogenic property of ginsenoside Rf from Panax ginseng via inhibition of CREB/MITF pathway in melanocytes and ex vivo human skin
Panax ginseng root extract · Journal of Ginseng Research, 2021Enhancement of Chemical Stability and Dermal Delivery of Cordyceps militaris Extracts by Nanoemulsion
Cordyceps militaris extract · Nanomaterials, 2020A pilot randomized double-blind placebo-controlled trial on topical chamomile (Matricaria chamomilla L.) oil for severe carpal tunnel syndrome
Chamomile extract, Chamomile flower extract · Complementary Therapies in Clinical Practice, 2015Snail Slime Extracted by a Cruelty Free Method Preserves Viability and Controls Inflammation Occurrence: A Focus on Fibroblasts
Snail mucin · Molecules, 2023Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy
Centella asiatica extract, Madecassoside, Centella asiatica stem extract flower leaf, Centella asiatica leaf extract, Centella asiatica leaf water, Centella asiatica · Molecules, 2023In vivo anti-ageing activity of cream containing niosomes loaded with purple glutinous rice (Oryza sativa Linn.) extract
Rice extract · International Journal of Cosmetic Science, 2020A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Gluconolactone, Pha polyhydroxy acid · The Australasian Journal of Dermatology, 1992Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula
Galactomyces ferment filtrate, Saccharomyces rice ferment filtrate, Saccharomyces rice bran ferment, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Saccharomyces ferment filtrate · Journal of Clinical Medicine, 2021Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin
Acetyl hexapeptide-8 · Annals of Dermatology, 2019Tremella fuciformis polysaccharides inhibit UVA-induced photodamage of human dermal fibroblast cells by activating up-regulating Nrf2/Keap1 pathways
Tremella fuciformis polysaccharide · Journal of Cosmetic Dermatology, 2021Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)
Chrysanthemum parthenium extract · Inflammopharmacology, 2009Phyllanthus emblica L. (amla) branch: A safe and effective ingredient against skin aging
1 · Journal of Traditional and Complementary Medicine, 2021Double-blind, randomized, placebo-controlled study of a lotion containing triethyl citrate and ethyl linoleate in the treatment of acne vulgaris
Triethyl citrate · The British Journal of Dermatology, 2007Taurine bromamine (TauBr)--its role in immunity and new perspectives for clinical use
Taurine · Journal of Biomedical Science, 2010Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study
Salicylic acid, Microclear technology, Bha beta hydroxy acid · Journal of Cosmetic Dermatology, 2024Tremella fuciformis Inhibits Melanogenesis in B16F10 Cells and Promotes Migration of Human Fibroblasts and Keratinocytes
Tremella fuciformis polysaccharide · In Vivo, 2022Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects
Vitamin e · Journal of Cosmetic Dermatology, 2020The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro
Bifida ferment filtrate, Bifida lysate ferment · Journal of Cosmetic Dermatology, 2023High-Payload Nanosuspension of Centella asiatica Extract for Improved Skin Delivery with No Irritation
Asiaticoside · International Journal of Nanomedicine, 2021Inhibition of TRPV1 prevented skin irritancy induced by phenoxyethanol. A preliminary in vitro and in vivo study
Phenoxyethanol · International Journal of Cosmetic Science, 2017Comparative Study of 35% Glycolic Acid, 20% Salicylic-10% Mandelic Acid, and Phytic Acid Combination Peels in the Treatment of Active Acne and Postacne Pigmentation
Phytic acid · Journal of Cutaneous and Aesthetic Surgery, 2019Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach
Zinc · Journal of Controlled Release, 2025Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function
Rosmarinus officinalis oil leaf rosemary oil leaf · International Journal of Molecular Sciences, 2022Improvement of acne vulgaris by topical fullerene application: unique impact on skin care
Fullerenes · Nanomedicine, 2011Night Cream Containing Melatonin, Carnosine and Helichrysum italicum Extract Helps Reduce Skin Reactivity and Signs of Photodamage: Ex Vivo and Clinical Studies
Densiflore · Dermatology and Therapy, 2020Natural Arctium lappa fruit extract improves the clinical signs of aging skin
Arctium lappa root extract · Journal of Cosmetic Dermatology, 2008A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid
Ceramide np, Moisturizing lipid, 3 essential ceramides · Skin Pharmacology and Physiology, 2022Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment
Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications
Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2015Acid-base combination principles for preparation of anti-acne dissolving microneedles loaded with azelaic acid and matrine
Sophora flavescens root extract · European Journal of Pharmaceutical Sciences, 2021A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide
Salicylic acid, Microclear technology, Bha beta hydroxy acid · Journal of Drugs in Dermatology, 2023The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
2-hexanediol · International Journal of Cosmetic Science, 2011Effects of a lotion containing probiotic ferment lysate as the main functional ingredient on enhancing skin barrier: a randomized, self-control study
1 · Scientific Reports, 2023Chemical peels for acne vulgaris: a systematic review of randomised controlled trials
Mandelic acid · BMJ Open, 2018Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs
Vitamin e · Journal of Cosmetic Dermatology, 2022Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study
N.m.f · Molecules, 2021Preparation and evaluation of benzalkonium chloride hand sanitizer as a potential alternative for alcohol-based hand gels
Benzalkonium chloride · Saudi Pharmaceutical Journal, 2021Colloidal Oatmeal <em>(Avena Sativa)</em> Improves Skin Barrier Through Multi-Therapy Activity
Avena sativa kernel extract oat kernel extract · Journal of Drugs in Dermatology, 2016Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial
Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial
Ginkgo biloba leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2015In Vivo skin hydration and anti-erythema effects of Aloe vera, Aloe ferox and Aloe marlothii gel materials after single and multiple applications
Aloe ferox leaf extract · Pharmacognosy Magazine, 2014Topical application of superoxide dismutase mediated by HIV-TAT peptide attenuates UVB-induced damages in human skin
Superoxide dismutase · European Journal of Pharmaceutics and Biopharmaceutics, 2016Spent Yeast Waste Streams as a Sustainable Source of Bioactive Peptides for Skin Applications
Yeast · International Journal of Molecular Sciences, 2023In vitro and in vivo anti-allergic effects of Arctium lappa L
Arctium lappa root extract · Experimental Biology and Medicine, 2008Encapsulation of alpha arbutin, a depigmenting agent, in nanosized ethosomes: Invitro and invivo human studies
Alpha-arbutin · Heliyon, 2023Efficacy and safety of non-thermal nitrogen plasma versus long-pulsed Nd:YAG laser for hand rejuvenation
Nitrogen · Lasers in Medical Science, 2022Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function
Propanediol · International Journal of Cosmetic Science, 2024Camellioside A, isolated from Camellia japonica flowers, attenuates UVA-induced production of MMP-1 in HaCaT keratinocytes via suppression of MAPK activation
Camellia japonica flower extract · Experimental and Therapeutic Medicine, 2021Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial
Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study
Zinc gluconate · Clinical, Cosmetic and Investigational Dermatology, 2023Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations
Vitamin e · Journal of Cosmetic Dermatology, 2022Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release
Oenothera biennis oil, Oenothera biennis flower extract · Biomaterials Advances, 2022Natural Sulfurs Inhibit LPS-Induced Inflammatory Responses through NF-κB Signaling in CCD-986Sk Skin Fibroblasts
Dimethyl sulfone · Life, 2021Comparison of the Efficacy of Atopalm(®) Multi-Lamellar Emulsion Cream and Physiogel(®) Intensive Cream in Improving Epidermal Permeability Barrier in Sensitive Skin
Mle multi-lamellar emulsion · Dermatology and Therapy, 2016Efficacy and tolerability of the investigational topical cream SD-101 (6% allantoin) in patients with epidermolysis bullosa: a phase 3, randomized, double-blind, vehicle-controlled trial (ESSENCE study)
Allantoin · Orphanet Journal of Rare Diseases, 2020Protective Effects of Fermented Houttuynia cordata Against UVA and H2O2-Induced Oxidative Stress in Human Skin Keratinocytes
Medicinal wheat extract, Heart leaf extract · Applied Biochemistry and Biotechnology, 2023Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin
Magnesium ascorbyl phosphate · Photochemistry and Photobiology, 2012A Rose Extract Protects the Skin against Stress Mediators: A Potential Role of Olfactory Receptors
Rose extract · Molecules, 2020Evaluating the Safety and Efficacy of a Topical Formulation Containing Epidermal Growth Factor, Tranexamic Acid, Vitamin C, Arbutin, Niacinamide and Other Ingredients as Hydroquinone 4% Alternatives to Improve Hyperpigmentation: A Prospective, Randomized, Controlled Split Face Study
Arbutin · Journal of Cosmetic Science, 2020Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial
Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020Challenging the safety and efficacy of topically applied chlorogenic acid, apigenin, kaempferol, and naringenin by HET-CAM, HPLC-TBARS-EVSC, and laser Doppler flowmetry
Grapefruit seed extract · Frontiers in Chemistry, 2024Carboxymethyl cellulose-based hydrogel film combined with berberine as an innovative tool for chronic wound management
Coptis japonica extract · Carbohydrate Polymers, 2022Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract
Camellia sinensis leaf extract, Camellia sinensis leaf water, Aloe barbadensis flower extract · Clinical, Cosmetic and Investigational Dermatology, 2019Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris
Citric acid, Capryloyl salicylic acid · Journal of Cosmetic Dermatology, 2021The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study
Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017Positive and ecobiological contribution in skin photoprotection of ectoine and mannitol combined in vivo with UV filters
Mannitol · Journal of Cosmetic Dermatology, 2024In Vitro and Clinical Safety Assessment of the Multiple W/O/W Emulsion Based on the Active Ingredients from Rosmarinus officinalis L., Avena sativa L. and Linum usitatissimum L
Avena sativa kernel extract oat kernel extract · Pharmaceutics, 2021Amino acid complex (AAComplex) benefits in cosmetic products: In vitro and in vivo clinical studies
Aacomplex · Journal of Cosmetic Dermatology, 2022Formulation and evaluation of antisebum secretion effects of sea buckthorn w/o emulsion
Hippophae rhamnoides fruit extract · Journal of Pharmacy & Bioallied Sciences, 2010Photoprotective effect of black tea extracts against UVB-induced phototoxicity in skin
Black tea · Photochemistry and Photobiology, 1999Saponins of Korean Red Ginseng May Protect Human Skin from Adipokine-Associated Inflammation and Pigmentation Resulting from Particulate Matter Exposure
Saponins · Nutrients, 2022Is benzyl alcohol a significant contact sensitizer?
Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022Whitening effect of alpha-bisabolol in Asian women subjects
Bisabolol · International Journal of Cosmetic Science, 2010Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison
Willow bark extract, Willow water bark, Salix nigra bark extract willow bark extract · Journal of Cosmetic Dermatology, 2019Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract
Willow bark extract, Licorice extract, Glycyrrhiza glabra leaf extract licorice leaf extract, Willow water bark, Salix nigra bark extract willow bark extract · Planta Medica, 2019An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging
Willow bark extract, Salix nigra bark extract willow bark extract · Journal of Cosmetic Dermatology, 2010Understanding Solar Skin Elastosis-Cause and Treatment
Witch hazel leaf water, Witch hazel, Witch hazel water, Witch hazel extract, Witch hazel extract bark twig leaf · Journal of Cosmetic Science, 2018Inhibitory effects of shell of Camellia oleifera Abel extract on mushroom tyrosinase and human skin melanin
Butylene glycol · Journal of Cosmetic Dermatology, 2019Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study
Beta-glucan · Journal of Cosmetic Dermatology, 2021Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers
Sodium ascorbyl phosphate · Drug Research, 2017Cosmetic Formulations with Melaleuca alternifolia Essential Oil for the Improvement of Photoaged Skin: A Double-Blind, Randomized, Placebo-Controlled Clinical Study
Melaleuca alternifolia tree extract, Melaleuca alternifolia leaf extract · Photochemistry and Photobiology, 2023Apple Extract (Malus sp.) and Rutin as Photochemopreventive Agents: Evaluation of Ultraviolet B-Induced Alterations on Skin Biopsies and Tissue-Engineered Skin
Pyrus malus fruit extract · Rejuvenation Research, 2020Exploring the Therapeutic Potential of Green Tea (Camellia sinensis L.) in Anti-Aging: A Comprehensive Review of Mechanisms and Findings
Camellia sinensis extract · Mini Reviews in Medicinal Chemistry, 2025Parthenolide-depleted Feverfew (Tanacetum parthenium) protects skin from UV irradiation and external aggression
Chrysanthemum parthenium extract · Archives of Dermatological Research, 2008Assessment of Cosmetic and Dermatological Properties and Safety of Use of Model Skin Tonics with Kombucha-Fermented Red Berry Extracts
Saccharomyces xylinum black tea ferment · International Journal of Molecular Sciences, 2022Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin
Capryloyl salicylic acid, Lipo-hydroxy acid · Journal of Cosmetic Dermatology, 2008Annurca Apple Oleolite as Functional Ingredient for the Formulation of Cosmetics with Skin-Antiaging Activity
1 · International Journal of Molecular Sciences, 2024Improvement of Biophysical Skin Parameters of Topically Applied Fermented Soybean Extract-Loaded Niosomes with No Systemic Toxicity in Ovariectomized Rats
Glycine seed extract soybean seed extract · Pharmaceutics, 2021Use of the synthetic superoxide dismutase/catalase mimetic EUK-134 to compensate for seasonal antioxidant deficiency by reducing pre-existing lipid peroxides at the human skin surface
Superoxide dismutase · International Journal of Cosmetic Science, 2004Taif Rose Oil Ameliorates UVB-Induced Oxidative Damage and Skin Photoaging in Rats via Modulation of MAPK and MMP Signaling Pathways
Rosa damascena oil rose oil · ACS Omega, 2023Skin improvement and stability of Echinacea purpurea dermatological formulations
Echinacea purpurea extract · International Journal of Cosmetic Science, 2010Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration
Betaine, Aloe barbadensis flower extract · Molecules, 2024Repair of acetone- and sodium lauryl sulphate-damaged human skin barrier function using topically applied emulsions containing barrier lipids
Phytosphingosine · Journal of the European Academy of Dermatology and Venereology, 2002Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol
Sorbitol · Journal of Cosmetic Science, 2013Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement
Adenosine · Journal of Cosmetic Dermatology, 2019Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders
3-o-ethyl ascorbic acid · Polymers, 2023Effects of UV Rays and Thymol/Thymus vulgaris L. Extract in an ex vivo Human Skin Model: Morphological and Genotoxicological Assessment
Thymus vulgaris leaf extract · Cells, Tissues, Organs, 2016Stability, antioxidant activity, in vivo safety and efficacy of creams with standardized wild apple fruit extract: a comparison of conventional and biodegradable emulsifiers
Pyrus malus fruit extract · International Journal of Cosmetic Science, 2019Antiaging, Brightening, and Antioxidant Efficacy of Fermented Bilberry Extract (Vaccinium myrtillus): A Randomized, Double-Blind, Placebo-Controlled Trial
Vaccinium myrtillus fruit extract · Nutrients, 2024Effects of lactobionic acid peel, aluminum oxide crystal microdermabrasion, and both procedures on skin hydration, elasticity, and transepidermal water loss
Lactobionic acid · Journal of Cosmetic Dermatology, 2019Betula alba Bark Extract and Empetrum nigrum Fruit Juice, a Natural Alternative to Niacinamide for Skin Barrier Benefits
Betula alba juice, Bark tree · International Journal of Molecular Sciences, 2022Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment
Asiatic acid, Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024Standardized extract of wild apple fruit in alkyl-polyglucoside-based cosmetic cream - estimation of stability, safety, antioxidant activity and efficiency
Pyrus malus fruit water · International Journal of Cosmetic Science, 2018Withania somnifera extract attenuates stem cell factor-stimulated pigmentation in human epidermal equivalents through interruption of ERK phosphorylation within melanocytes
Ashwagandha · Journal of Natural Medicines, 2012Effect of facial application of essence containing royal jelly extract on stratum corneum moisture content: A placebo-controlled, double-blind, parallel-group study
Royal jelly, Royal jelly extract · Journal of Cosmetic Dermatology, 2022Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast
Squalane · Molecules, 2025Redefining face contour with a novel anti-aging cosmetic product: an open-label, prospective clinical study
Alteromanas extract ferment, Pseudoalteromonas exopolysaccharides · Clinical, Cosmetic and Investigational Dermatology, 2017Development of grape seed extract based formulations by using non-invasive biophysical technique and its impact on skin aging
Vitis vinifera seed extract grape seed extract · Pakistan Journal of Pharmaceutical Sciences, 2021Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine
Acetyl glucosamine · Advanced Pharmaceutical Bulletin, 2016Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid
Betaine · Pharmaceutics, 2024Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025Lipid ingredients in moisturizers can modulate skin responses to UV in barrier-disrupted human skin in vivo
Phytosphingosine · Journal of Dermatological Science, 2012Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota
Camellia sinensis leaf extract · Molecules, 2024Gene expression profile of human follicle dermal papilla cells in response to Camellia japonica phytoplacenta extract
Camellia japonica flower extract · FEBS Open Bio, 2021Treatment of Postinflammatory Hyperpigmentation Following Acne With Microneedling and Panax Ginseng-Derived Exosomes
Panax ginseng root extract · Plastic and Reconstructive Surgery. Global Open, 2025Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis
Vinolevure, Yeast extract · Journal of Clinical Medicine, 2023Dyspigmentation, skin physiology, and a novel approach to skin lightening
Vinolevure · Journal of Cosmetic Dermatology, 2013Randomized prospective study of low-dose isotretinoin alone and combination with salicylic acid and mandelic peel against acne tarda
Mandelic acid · Journal of Cosmetic Dermatology, 2022Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception
N.m.f · Skin Research and Technology, 2022Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application
Cyclodextrin · International Journal of Cosmetic Science, 2021Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres
Carica papaya fruit extract, Papain · Giornale Italiano Di Dermatologia E Venereologia, 2015Salicyloyl-phytosphingosine: a novel agent for the repair of photoaged skin
Phytosphingosine · International Journal of Cosmetic Science, 2007Design and in vivo evaluation of emulgel formulations including green tea extract and rose oil
Rosa damascena oil flower, Damask roses, Rosa damascena oil rose oil · Acta Pharmaceutica, 2013Clinical and sebumetric evaluation of topical emulsions in the treatment of acne vulgaris
Hippophae rhamnoides fruit extract · Postepy Dermatologii I Alergologii, 2014A novel topical ingredient derived from seaweed significantly reduces symptoms of acne vulgaris: a general literature review
Marine algae · Journal of Cosmetic Science, 2013Effects of Hydroxydecine(®) (10-hydroxy-2-decenoic acid) on skin barrier structure and function in vitro and clinical efficacy in the treatment of UV-induced xerosis
Royal jelly · European Journal of Dermatology, 2011Modulation of TRPV1 function by Citrus reticulata (tangerine) fruit extract for the treatment of sensitive skin
Extracts fruit · Journal of Cosmetic Dermatology, 2023Fabrication of polyvinyl pyrrolidone-K90/Eudragit RL100-based dissolving microneedle patches loaded with alpha-arbutin and resveratrol for skin depigmentation
Arbutin · Biomaterials Science, 2023Permeation, metabolism and site of action concentration of nicotinic acid derivatives in human skin. Correlation with topical pharmacological effect
Hexyl nicotinate · European Journal of Pharmaceutical Sciences, 2003Modulation of autophagy by an innovative phytocosmetic preparation (Myrothamnus flabelifolia and Coffea arabica) in human fibroblasts and its effects in a clinical randomized placebo-controlled trial
Myrothamnus flabellifolia stem extract leaf · Journal of Cosmetic Dermatology, 2022Influence of vitamin E acetate on stratum corneum hydration
Tocopheryl acetate vitamin e, Tocopheryl acetate · Arzneimittel-Forschung, 1998The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively
Betaine · Skin Research and Technology, 2003A randomized controlled study to evaluate the depigmenting activity of L-ascorbic acid plus phytic acid-serum vs. placebo on solar lentigines
Phytic acid · Journal of Cosmetic Dermatology, 2011Highly efficient and compatible shampoo for use after hair transplant
Chamomilla recutita oil flower matricaria oil flower · Clinical, Cosmetic and Investigational Dermatology, 2015Algae extract protection effect on oxidized protein level in human stratum corneum
Hadasei-3, Algae extract · Annals of the New York Academy of Sciences, 2004Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers
Sodium ascorbyl phosphate · Journal of Cosmetic Dermatology, 2021Skin recovery by Lavandula angustifolia leaf callus extract: Redox control of Nrf2 signaling
Lavandula angustifolia oil lavender oil, Lavender · Free Radical Biology & Medicine, 2025Semi-solid functionalized nanostructured lipid carriers loading thymol for skin disorders
Thymus vulgaris leaf extract · International Journal of Pharmaceutics, 2024Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid
Pha polyhydroxy acid, Lactobionic acid · Journal of Cosmetic Dermatology, 2010Comparison of topical purslane & topical 0.1% triamcinolone acetonide in the management of oral lichen planus - a double blinded clinical trial
Portulaca oleracea extract · BMC Oral Health, 2023Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters
Rosmarinus officinalis leaf extract rosemary leaf extract · Antioxidants, 2025Influence of Panax ginseng formulation on skin microbiota: A randomized, split face comparative clinical study
2-hexanediol · Journal of Ginseng Research, 2022Starch- and carboxymethyl cellulose-based films as active beauty masks with papain incorporation
Carica papaya fruit extract · International Journal of Biological Macromolecules, 2023Modulation of lipid fluidity likely contributes to the fructose/xylitol-induced acceleration of epidermal permeability barrier recovery
Xylitylglucoside · Archives of Dermatological Research, 2019Development of a cream formulation containing bee venom and other bee products
Royal jelly · Journal of Cosmetic Dermatology, 2022A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo
Aloe barbadensis flower extract · Journal of Cosmetic Dermatology, 2022Anti-inflammatory and skin-hydrating properties of a dietary supplement and topical formulations containing oligomeric proanthocyanidins
Vitis vinifera seed extract grape seed extract, Cranberry fruit extract, Grape seed extract · Skin Pharmacology and Physiology, 2007Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment
Moringa oleifera · Polymers, 2022Rosa gallica and its active compound, cyanidin-3,5-O-diglucoside, improve skin hydration via the GLK signaling pathway
Rosa gallica flower extract rose flower extract · BioFactors, 2023Clinical study of Asian skin changes after application of a sunscreen formulation containing grape seed extract
Grape seed extract · Journal of Cosmetic Dermatology, 2022Tremella fuciformis polysaccharides alleviates UV-provoked skin cell damage via regulation of thioredoxin interacting protein and thioredoxin reductase 2
Tremella fuciformis sporocarp extract · Photochemical & Photobiological Sciences, 2023Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study
Panthenol, Panthenol vitamin b5, Dexpanthenol · Journal of Cosmetic Dermatology, 2025Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer
Galactomyces ferment filtrate, Saccharomyces rice ferment filtrate, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Saccharomyces ferment filtrate · Journal of Clinical Medicine, 2022Instrumental, clinical and subjective evaluation of the efficacy of a cosmetic treatment for home use
Acetyl glucosamine · Journal of Cosmetic and Laser Therapy, 2019The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays
Xylitylglucoside, Propanediol, Xylitol · Molecules, 2021Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
2-hexanediol, Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects
Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study
Hydrolyzed hyaluronic acid, Hydrolyzed sodium hyaluronate · Aesthetic Plastic Surgery, 2026Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects
Sodium ascorbyl phosphate · Experimental Dermatology, 2012Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes
3-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025Modulating effects of oatmeal extracts in the sodium lauryl sulfate skin irritancy model
Avena sativa kernel extract oat kernel extract · Skin Pharmacology and Applied Skin Physiology, 2002Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin
Vitamin e · Journal of Cosmetic Dermatology, 2024Standardized wild apple fruit extract as a bioactive agent in dermocosmetic products for efficacy skin hydration-In vitro and in vivo evaluation
Pyrus malus fruit extract · Journal of Cosmetic Dermatology, 2022The effect of a vitamin A palmitate and antioxidant-containing oil-based moisturizer on photodamaged skin of several body sites
Retinyl palmitate · Journal of Cosmetic Dermatology, 2013A 10% Lactobionic acid-containing moisturizer reduces skin surface pH without irritation-An in vivo/in vitro study
Lactobionic acid · Journal of Cosmetic Dermatology, 2019Formulation and clinical evaluation of the standardized Litchi chinensis extract for skin hyperpigmentation and aging treatments
Litchi chinensis pericarp extract · Annales Pharmaceutiques Francaises, 2020Moisturizing effect of alcohol-based hand rub containing okra polysaccharide
Hibiscus esculentus fruit extract · International Journal of Cosmetic Science, 2012Inhibition of LPS-Induced Skin Inflammatory Response and Barrier Damage via MAPK/NF-κB Signaling Pathway by Houttuynia cordata Thunb Fermentation Broth
Houttuynia cordata extract, Medicinal wheat extract · Foods, 2024Combining Topical and Oral Botanicals for Skin Redness, Pigmentation, Sleep, and Mood: A Randomized Controlled Study
Ashwagandha, Theanine, Saffron extracts flower · Journal of Clinical Medicine, 2022Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Diglycerin · Journal of Oleo Science, 2016Three clinical studies showing the anti-aging benefits of sodium salicylate in human skin
Sodium salicylate · Journal of Cosmetic Dermatology, 2010Efficacy and Safety of a New Cosmeceutical Regimen Based on the Combination of Snail Secretion Filtrate and Snail Egg Extract to Improve Signs of Skin Aging
Snail secretion filtrate, Snail mucin · The Journal of Clinical and Aesthetic Dermatology, 2020Hexyl-nicotinate-induced vasodilation in normal human skin
Hexyl nicotinate · Dermatologica, 1987Towards a modern approach to traditional use of Helichrysum italicum in dermatological conditions: In vivo testing supercritical extract on artificially irritated skin
Densiflore · Journal of Ethnopharmacology, 2023Algae extract-based nanoemulsions for photoprotection against UVB radiation: an electrical impedance spectroscopy study
Algae extract · Scientific Reports, 2025Moisturizing effect of stable cream containing Crocus sativus extracts
Saffron extracts flower · Pakistan Journal of Pharmaceutical Sciences, 2014Poly-γ-Glutamic Acid from a Novel Bacillus subtilis Strain: Strengthening the Skin Barrier and Improving Moisture Retention in Keratinocytes and a Reconstructed Skin Model
Polyglutamic acid · International Journal of Molecular Sciences, 2025Functional properties and skin care effects of sodium trehalose sulfate
Trehalose · Skin Research and Technology, 2024Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy
Tocopheryl acetate vitamin e, Tocopheryl acetate · Scientific Reports, 2025Effect of isosecotanapartholide isolated from Artemisia princeps Pampanini on IL‑33 production and STAT‑1 activation in HaCaT keratinocytes
Artemisia princeps extract, Artemisia princeps leaf water, Artemisia princeps leaf extract · Molecular Medicine Reports, 2017Protective properties of Avène Thermal Spring Water on biomechanical, ultrastructural and clinical parameters of human skin
Thermal spring water, Thermal water mineral content, Water hungarian thermal water · Journal of the European Academy of Dermatology and Venereology, 2020Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris
Capryloyl salicylic acid, Citric acid, Lipo-hydroxy acid · Journal of Drugs in Dermatology, 2013Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Hydrolyzed hyaluronic acid, Hydrolyzed sodium hyaluronate · Colloids and Surfaces. B, Biointerfaces, 2022Improving the outcome of treating striae gravidarum by combined therapies using topical β-glucan and 1565-nm non-ablative fractional laser: A prospective randomized vehicle-controlled parallel group study
Beta-glucan · The Journal of Dermatology, 2022Treatment of Stretch Marks Using a New Formulation Combining Nanofractional Radiofrequency Plus Magnetic Nanofractional Radiofrequency
Beta-glucan · Dermatology and Therapy, 2023A method for maintaining the clinical results of 4% hydroquinone and 0.025% tretinoin with a cosmeceutical formulation
Vinolevure · Journal of Drugs in Dermatology, 2015κ-Carrageenan tetrasaccharide ameliorates particulate matter-induced defects in skin hydration of human keratinocytes cells and skin barrier disorders
Chondrus crispus extract · International Journal of Biological Macromolecules, 2025Quality attributes of partially hydrolyzed collagen in a liquid formulation used for skin care
Collagen water · Journal of Cosmetic Dermatology, 2021Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence
Adenosine · International Journal of Molecular Sciences, 2026A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females
Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients
3-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026Clinical study of a spray containing birch juice for repairing sensitive skin
Betula alba juice · Archives of Dermatological Research, 2023Effects of a Postbiotic Saccharomyces and Lactobacillus Ferment Complex on the Scalp Microbiome of Chinese Women with Sensitive Scalp Syndrome
Lactobacillus ferment · Clinical, Cosmetic and Investigational Dermatology, 2023Macrocystis pyrifera ferment-containing creams for optimizing facial skin rejuvenation
Macrocystis pyrifera extract · Journal of Cosmetic Dermatology, 2023Histometric assessment of the age-related skin response to 2-hydroxy-5-octanoyl benzoic acid
Capryloyl salicylic acid · Skin Pharmacology and Applied Skin Physiology, 1998Evaluation of additive effects of hydrolyzed jojoba (Simmondsia chinensis) esters and glycerol: a preliminary study
Hydrolyzed jojoba esters · Journal of Cosmetic Dermatology, 2008Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging
Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024The effects of topically applied hexyl nicotinate lotion on the cutaneous blood flow in patients with Raynaud's phenomenon
Hexyl nicotinate · The British Journal of Dermatology, 1988Chemical composition, skin microbiota metabolism, antimicrobial potential and anti-inflammatory properties of witch hazel bark (Hamamelis virginiana L.)
Hammelis virginiana witch hazel water · Journal of Ethnopharmacology, 2025Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum
Caprylic capric triglyceride · Life, 2023The Effectiveness and Safety of a Skin Care Product With Centella asiatica Leaf Extract, Ceramide NP, and Panthenol in Subjects With Sensitive Skin: A Prospective, Observational Study
3 essential ceramides · Journal of Cosmetic Dermatology, 2025Tasmannia lanceolata leaf extract alleviates stretch mark appearance in a randomized, placebo-controlled clinical trial in women and stimulates extracellular matrix synthesis in ex vivo human skin explants
Tasmannia lanceolata leaf extract fruit · Journal of Cosmetic Dermatology, 2021Ethanolamines permeate slowly across human skin ex vivo, but cause severe skin irritation at low concentrations
Ethanolamine · Archives of Toxicology, 2019Glycerol crosslinked vitamin E loaded xanthan gum and gellan gum nanoemulgels for topical management of dry skin
Xanthan gum · International Journal of Biological Macromolecules, 2025Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study
Galactomyces ferment filtrate, Saccharomyces rice ferment filtrate, Saccharomyces rice bran ferment, Pitera ferment filtrate galactomyces ferment filtrate, Galactomyces ferment filtrate pitera ferment filtrate, Saccharomyces ferment filtrate · Journal of Clinical Medicine, 2023Effects of Malaysian thermal spring water as adjunct therapy for mild to moderate acne vulgaris - a prospective, randomised, controlled, split face study
Thermal spring water, Thermal water mineral content, Water hungarian thermal water · The Medical Journal of Malaysia, 20245-α reductase inhibition by Epilobioum fleischeri extract modulates facial microbiota structure
Epilobium fleischeri extract · International Journal of Cosmetic Science, 2022Pleiotropic effects of a Camellia sinensis leaf extract on in vitro and in vivo skin health characteristics
Hadasei-3, Camellia sinensis leaf water · International Journal of Cosmetic Science, 2025Rapid and Visible Efficacy of a Dermocosmetic in Acne Patients With Fair Skin Phototypes: Results of a Randomized Split-Face Study
Zinc gluconate · Journal of Cosmetic Dermatology, 2026Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
Ascorbyl glucoside, Arginine · International Journal of Molecular Sciences, 2024A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
Pha polyhydroxy acid · Cutis, 2004Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling
Portulaca oleracea extract, Lactobacillus portulaca oleracea extract ferment · Cutaneous and Ocular Toxicology, 2022Recovery effects of various skin lipid components and their structural derivatives on skin barrier damage
Moisturizing lipid · International Journal of Cosmetic Science, 2026Real-world experience with a treatment with a skincare regimen of products containing the Macrocystis pyrifera ferment for optimizing facial skin rejuvenation
Macrocystis pyrifera extract · Journal of Cosmetic Dermatology, 2024The cutaneous effects of long-term use of Dead Sea mud on healthy skin: a 4-week study
Dead sea salt · International Journal of Dermatology, 2021Efficacy and safety of a facial serum and a mask containing salicylic acid and lipohydroxy acid in acne management: A randomized controlled trial
Lipo-hydroxy acid · Journal of Cosmetic Dermatology, 2023A cleanser formulated with Tris (hydroxymethyl) aminomethane and l-arginine significantly improves facial acne in male Thai subjects
Arginine · Journal of Cosmetic Dermatology, 2020Investigating the Effects of a Manuka Honey, Royal Jelly, and Bee Venom-Derived Face Serum on Skin Health and Signs of Aging
Royal jelly, Royal jelly extract · Cureus, 2025Enhanced Whitening Effect of the Formulations via Inhibition of Tyrosinase Activity by Combination of 4-n-Butylresorcinol, Licochalcone A and Glabridin at an Optimal Ratio
Glycyrrhiza glabra root extract · Skin Research and Technology, 2026Photoprotective Effects of Quercetin and Hesperidin in Polymorphous Light Eruption: A Comparative Study with Alpha-Glucosylrutin
Citrus aurantium dulcis peel extract · Current Issues in Molecular Biology, 2025Efficacy and safety of a facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glaba root extract in the treatment of maskne: A randomized placebo-controlled study
Snail secretion filtrate, Snail mucin · Journal of Cosmetic Dermatology, 2022Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from Paeonia lactiflora
Pdrn polydeoxyribonucleotide · International Journal of Molecular Sciences, 2025The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration
Lens esculenta fruit extract · Journal of Cosmetic Dermatology, 2024Potassium 4-Methoxysalicylate (4MSK) Exerts a Skin Lightening Effect by Acting on Melanocytes and Keratinocytes
Potassium · Journal of Cosmetic Dermatology, 2025Evaluation of vulvar irritancy potential of a menstrual pad containing sodium bicarbonate in short-term application
Bicarbonates · The Journal of Reproductive Medicine, 1991An integrated network pharmacology and molecular docking approach to reveal the role of Arctigenin against Cutibacterium acnes-induced skin inflammation by targeting the CYP19A1
Arctium lappa root extract · Chemical Biology & Drug Design, 2024Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial
Butyrospermum parkii butter shea butter, Saccharide isomerate, Argania spinosa kernel oil, Argan oil · Lasers in Medical Science, 2025Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial
Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color
Galactomyces ferment filtrate, Saccharomyces rice ferment filtrate, Saccharomyces ferment filtrate · Skinmed, 2021Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters
Gluconolactone · Skin Research and Technology, 2023Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin
Portulaca oleracea extract, Lactobacillus portulaca oleracea extract ferment · Cutaneous and Ocular Toxicology, 2025Augmented Skin Beneficial Effects of Thermus Thermophilus and Bacillus Subtilis Mixed-Culture Ferment Extract by Tripeptide GHK-Cu
Copper tripeptide-1, Copper peptides · Skin Research and Technology, 2026A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study
Saccharide isomerate · The Journal of Dermatological Treatment, 2025Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population
Saccharide isomerate · Journal of Cosmetic Dermatology, 2023The harnessing potential of carboxymethyl beta glucan: A driver of skin repair
Sodium carboxymethyl betaglucan · International Journal of Cosmetic Science, 2026Iontophoretic Delivery of Hyaluronic Acid Nanogel-Loaded Fermented Rice Extract Mitigates Skin Glycation
Rice extract · International Journal of Nanomedicine, 2025Synergistic combination: Developing a natural carrier-free assembled gel through hydrogen bond reconstruction strategy for efficient skin photo-damage restoration
Sodium pca · Biomaterials Advances, 2026Hydroxyethyl cellulose as carbohydrate polymer scaffold for surfactant-free serums with enhanced hydration and structural stability
Hydroxyethylcellulose · International Journal of Biological Macromolecules, 2026Structure/property comparisons of chemistries based on renewable 1,3-propanediol and petroleum-derived alkylene oxides
Propanediol · Journal of Cosmetic Science, 2017Simmondsia chinensis (jojoba) cake fermentation: A new, sustainable technology for advanced skin and scalp care ingredients
Lactobacillus ferment · International Journal of Cosmetic Science, 2026A Topical Formulation Containing Macrocystis Pyrifera Ferment for Managing Barrier Damage After Mild-Moderate Skin Disruption from Cosmetic Dermatologic Procedures
Macrocystis pyrifera extract · The Journal of Clinical and Aesthetic Dermatology, 2025Does Salt and Mineral Content of Dead Sea Mud Affect Its Irritation Potential: A Laser Doppler Flowmetry Study
Dead sea salt · Journal of Cosmetic Science, 2019The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial
Montmorillonite · Journal of Cosmetic Dermatology, 2025Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging: A Randomized, Double-Blinded, Active- and Vehicle-Controlled Clinical Trial
Hexapeptide-9 · Journal of Cosmetic Dermatology, 2025Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Tripeptide-1, Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea: A randomized clinical trial
Camellia sinensis leaf water · Journal of Cosmetic Dermatology, 2023Anti-ageing activities of nanovesicles derived from Artemisia princeps in human dermal cells and human skin model
Artemisia princeps leaf water · Journal of Extracellular Biology, 2025Virtual Screening-Guided Discovery of a Selective TRPV1 Pentapeptide Inhibitor with Topical Anti-Allergic Efficacy
Pentapeptide · Cells, 2026A Single-Center, Randomized, Double-Blind, Placebo-Controlled Clinical Trial of the Effectiveness of ANT1 Soybean Extract Cream on Skin Recovery After Nd: YAG Laser Treatment
Glycine seed extract soybean seed extract · Annals of Plastic Surgery, 2018The effect of a serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate and gluconolactone on skin biomarkers, wrinkles and skin texture: Ex vivo and clinical studies
Laminaria digitata extract · International Journal of Cosmetic Science, 2026Evaluation of Saponin-Rich Callus from Saponaria officinalis L. as a Novel Scrub Material with Significant Exfoliating and Anti-Inflammatory Effects
Saponins · Plants, 2025Isolation and characterization of Aureobasidium pullulans from rose rhizosphere: A novel source for skin benefits
Aureobasidium pullulans ferment · International Journal of Cosmetic Science, 2026Acai Oil-Based Organogel Containing Hyaluronic Acid for Topical Cosmetic: In Vitro and Ex Vivo Assessment
Euterpe oleracea fruit extract · Pharmaceutics, 2024Skin metabolomic response to medicinal shrub Myrothamnus flabellifolia and effect on skin phenotypes
Myrothamnus flabellifolia stem extract leaf · Scientific Reports, 2026Successful Combination of Ulvans and Thermal Spring Waters from as Burgas (Ourense) for Hydrating Cosmetic Creams in Healthy Volunteers
Vichy thermal water · Marine Drugs, 2026