Cetaphil Redness Relieving Night Moisturizer for acne-prone skin
Allantoin
Niacinamide
Panthenol Vitamin B5
Tocopheryl Acetate Vitamin E
Ceramide NpHigh
- HighCombination Skin Fit
- AverageEffectiveness
- HighSafety
A great choice for acne-prone skin; a few moisturizers fit it even better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate suitability for your combination skin, as niacinamide helps regulate oil production and sodium hyaluronate provides essential hydration. Shea butter offers some soothing benefits for your acne-prone skin, but it is not a primary concern addressed by this formula.
- The product is safe for your combination skin, with no harsh ingredients that could cause irritation.
- It provides excellent moisturizing benefits, which can support overall skin health.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
People Say
★4.4Overall rating based on 3.4k+ reviewsMany users report a visible reduction in redness and a calmer complexion by morning. A subset of reviewers find it functions better as a gentle maintenance moisturizer rather than a treatment that actively eliminates existing redness.
Highlights
Gentle & soothing Often Mentioned
- “feels soothing”
- “stops burning”
- “cools skin”
- “no stinging”
Lightweight texture Often Mentioned
- “absorbs quickly”
- “not greasy”
- “lightweight feel”
- “doesn't feel heavy”
Reduces redness Often Mentioned
- “less red in morning”
- “skin looks balanced”
- “stopped the flushing”
Fragrance-free Sometimes Noted
- “no scent”
- “doesn't irritate nose”
- “great for sensitive skin”
- “no chemical smell”
Hydrating Sometimes Noted
- “skin feels soft”
- “good moisture”
- “eliminates dry patches”
- “hydrates overnight”
Ineffective on redness Sometimes Noted
- “didn't help redness”
- “just a moisturizer”
- “no change in color”
- “redness persisted”
Caused irritation Rarely Noted
- “burned my face”
- “caused breakout”
- “stung upon application”
- “made face redder”
Packaging issues Rarely Noted
- “pump stopped working”
- “hard to get last bit”
- “defective dispenser”
- “wasteful bottle”
Small quantity Rarely Noted
- “bottle is tiny”
- “expensive for size”
- “runs out fast”
- “wish it was bigger”
Texture too thin Rarely Noted
- “too watery”
- “runny consistency”
- “not rich enough”
- “need more moisture”
Sources: lovi.care, walmart.com, target.com, iherb.com, cetaphil.com, walgreens.com, and more
Questions and answers
What makes Redness Relieving Night Moisturizer a great fit for acne-prone skin?
This moisturizer is a great fit because niacinamide helps regulate oil production while gentle hydrators and soothing ingredients calm the skin without causing irritation. It has a safe profile with no harsh components, and its moisturizing benefits support overall skin health.
American Journal of Clinical Dermatology, 2002Contemporary Clinical Trials Communications, 2021
Which ingredients make this cream a good fit for acne-prone skin?
Niacinamide makes this cream a great fit for your acne-prone skin by helping regulate oil production, while sodium hyaluronate provides essential hydration. Additionally, allantoin and panthenol help calm irritation, and tocopheryl acetate is unlikely to clog pores.
American Journal of Clinical Dermatology, 2002Contemporary Clinical Trials Communications, 2021
What does Allantoin do for acne-prone skin?
Allantoin helps calm redness and supports the skin barrier, making it a soothing addition to routines for acne-prone skin. It is often paired with ingredients that clear pores and reduce oil to keep acne-prone skin balanced and comfortable.
What does Niacinamide do for acne-prone skin?
Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Where does this cream go in a skincare routine for acne-prone skin?
This cream goes as the moisturizer step in your evening routine, right after your treatment. It helps keep your skin calm and hydrated without clogging pores.
Can I use this cream with retinol, and in what order?
You can use this cream alongside retinol by applying the retinol first and following it with this moisturizer. Using a barrier-supporting moisturizer alongside retinoids helps reduce dryness and irritation while keeping your skin calm.
How often should I use this cream?
You can use this moisturizing treatment daily as part of your morning and evening routine. Regular application helps keep your skin hydrated and supports overall skin health with a very safe profile.
Can this cream clog pores, cause breakouts or purging for acne-prone skin?
This cream is unlikely to clog pores or cause breakouts on acne-prone skin, as its ingredients show a safe profile for skin texture. It provides great moisturizing benefits and gentle care without harsh elements that typically cause irritation.
Can I use this cream around the eyes or on my body?
You can use this moisturizing treatment around your eyes and on your body, as its safe formula is unlikely to cause irritation. Panthenol helps keep skin hydrated and calm while vitamin E supports a healthy skin barrier in these sensitive areas.
Surgical and Radiologic Anatomy, 2002American Journal of Clinical Dermatology, 2002
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol, behenyl alcohol, and cetyl alcohol are fatty alcohols, which soften the skin.
What the research says
Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.
Contemporary Clinical Trials Communications, 2021Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion.
International Journal of Dermatology, 2008A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin.
Skin Pharmacology and Physiology, 2022Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.
Aesthetic Plastic Surgery, 2018Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.
Arzneimittel-Forschung, 2000Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.
Auris, Nasus, Larynx, 2020Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.
Journal of Cosmetic Dermatology, 2025Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.
Journal of Cosmetic Dermatology, 2024A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use.
Journal of Cosmetic Dermatology, 2022
Ingredients
Water, Caprylic Capric Triglyceride, Glycerin, Propanediol, Pentylene Glycol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Sorbitol, Dimethicone, Butyrospermum Parkii Butter Shea Butter, Cetearyl Alcohol, Behenyl Alcohol, Glyceryl Stearate, Sodium Hydroxide, Tocopheryl Acetate, Allantoin, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Ceramide Np, Panthenol, Caffeine, Citric Acid, Cetyl Alcohol, Ceteareth-20, Glyceryl Stearate Citrate, Disodium Ethylene Dicocamide Peg-15 Disulfate, Niacinamide, Caprylyl Glycol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Disodium Edta, Xanthan Gum, Bht
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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