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Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes
Epigallocatechin gallate · The Journal of Investigative Dermatology, 2013Improvement of naturally aged skin with vitamin A (retinol)
Retinol · Archives of Dermatology, 2007Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo
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Ascorbic acid, Tocopherol vitamin e, Tocopherol · Journal of Cosmetic Dermatology, 2020A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation
Ferulic acid · Journal of the American Academy of Dermatology, 2008Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin
Ferulic acid · Journal of Cosmetic Dermatology, 2008Effects of menthol and cold on histamine-induced itch and skin reactions in man
Peppermint leaf extract · Neuroscience Letters, 1995Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Retinol · International Journal of Cosmetic Science, 2017Anti-microbial and -inflammatory activity and efficacy of phytosphingosine: an in vitro and in vivo study addressing acne vulgaris
Phytosphingosine · International Journal of Cosmetic Science, 2007Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing
Retinol, Bakuchiol · The British Journal of Dermatology, 2019Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Ascorbyl glucoside · Journal of Periodontology, 2009Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women
Glutathione · Clinical, Cosmetic and Investigational Dermatology, 2014Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo
Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter
Titanium dioxide · International Journal of Cosmetic Science, 2000The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction
Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects
Ubiquinone · BioFactors, 2015Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations
Aloe barbadensis leaf juice · Clinical Pharmacology, 2018Urea: a comprehensive review of the clinical literature
Urea · Dermatology Online Journal, 2013A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin
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Ceramides · Scientific Reports, 2022Topical benzoyl peroxide for acne
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Ascorbic acid · Clinical Oral Investigations, 2021Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin
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Retinyl palmitate · International Journal of Nanomedicine, 2021Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls
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Azelaic acid · Pharmaceutics, 2021The clinical effect of glutathione on skin color and other related skin conditions: A systematic review
Glutathione · Journal of Cosmetic Dermatology, 2019The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study
Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy
Niacinamide · Journal of Cosmetic Dermatology, 2021Niacinamide mitigates SASP-related inflammation induced by environmental stressors in human epidermal keratinocytes and skin
Gentlebright complex · International Journal of Cosmetic Science, 2020The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide
Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure
Benzoyl peroxide · Journal of Shoulder and Elbow Surgery, 2021Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling
Leontopodium alpinum extract · Genes, 2020Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial
Acetyl glucosamine · The British Journal of Dermatology, 2010Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
Acetyl glucosamine · Journal of Cosmetic Dermatology, 2007Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug
Benzoyl peroxide · American Journal of Clinical Dermatology, 2022Two superior antioxidants: Ferulic acid and ascorbic acid in reducing signs of photoaging-A split-face comparative study
Sodium ascorbyl phosphate ascorbic acid · Dermatologic Therapy, 2022A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0.02% tretinoin product regimen
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Niacinamide · Scientific Reports, 2024A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population
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Ascorbyl palmitate ascorbic acid · Antioxidants, 2024Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration
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Mandelic acid · Journal of Cosmetic Dermatology, 2020Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant
Caffeine · Frontiers in Physiology, 2019Structural characterization and in vivo evaluation of retinyl palmitate in non-ionic lamellar liquid crystalline system
Retinyl palmitate · Colloids and Surfaces. B, Biointerfaces, 2011A Dunaliella salina Extract Counteracts Skin Aging under Intense Solar Irradiation Thanks to Its Antiglycation and Anti-Inflammatory Properties
Dunaliella salina extract · Marine Drugs, 2022Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial
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Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days
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Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021Topical glutathione amino acid precursors protect skin against environmental and oxidative stress
Glutathione · Journal of the European Academy of Dermatology and Venereology, 2024An Open-Label Single-Arm, Monocentric Study Assessing the Efficacy and Safety of Natural Pterostilbene (Pterocarpus marsupium) for Skin Brightening and Antiaging Effects
Blueberry fruit extract · Clinical, Cosmetic and Investigational Dermatology, 2020In vivo anti-ageing activity of cream containing niosomes loaded with purple glutinous rice (Oryza sativa Linn.) extract
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Azelaic acid · Dermatology and Therapy, 2024Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies
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Hexylresorcinol · International Journal of Cosmetic Science, 2022Chemical peels for acne vulgaris: a systematic review of randomised controlled trials
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Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers
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Willow bark extract · Planta Medica, 2019Apple Extract (Malus sp.) and Rutin as Photochemopreventive Agents: Evaluation of Ultraviolet B-Induced Alterations on Skin Biopsies and Tissue-Engineered Skin
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Pyrus malus fruit extract · Journal of Cosmetic Dermatology, 2022TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection
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Tocopheryl acetate · Scientific Reports, 2025Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
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Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021Facial disbiosis and UV filters
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Bakuchiol · Skin Research and Technology, 2026Noninvasive Monitoring of Palmitoyl Hexapeptide-12 in Human Skin Layers: Mechanical Interaction with Skin Components and Its Potential Skincare Benefits
Palmitoyl hexapeptide-12 · ACS Applied Bio Materials, 2025Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
Ascorbyl glucoside · International Journal of Molecular Sciences, 2024Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling
Portulaca oleracea extract purslane extract · Cutaneous and Ocular Toxicology, 2022Topical application of retinyl propionate, 4 hexyl resorcinol, and niacinamide reverses molecular and clinical features of ageing
Retinyl propionate · International Journal of Cosmetic Science, 2024Retinyl propionate and climbazole combination demonstrates clinical improvement to the appearance of hyperpigmentation and deep wrinkling with minimal irritation
Retinyl propionate · International Journal of Cosmetic Science, 2017Synergistic combination: Developing a natural carrier-free assembled gel through hydrogen bond reconstruction strategy for efficient skin photo-damage restoration
Sodium pca · Biomaterials Advances, 2026Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial
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Saccharide isomerate · The Journal of Dermatological Treatment, 2025