Good Molecules vs Shiseido
Good Molecules and Shiseido are a 2019 American skincare brand owned by Beautylish, Inc. and an 1872 Japanese skincare brand owned by Shiseido Company, Limited, respectively. The former is widely loved for its thoughtful range of serums, moisturizers, eye products, exfoliants, and more, which are formulated with key ingredients like glycerin and hyaluronic acid, while the latter is beloved for its thoughtful array of moisturizers, cleansers, sunscreens, serums, and more, all formulated with key ingredients like glycerin. Good Molecules suits combination skin and oily acne-prone skin best, whereas the brand from Japan suits sensitive skin and mature skin best, offering gentle yet effective daily care. They differ primarily in their specific target audiences and distinct ingredient profiles, as the American line utilizes glycerin to improve skin hydration and restore barrier function alongside hyaluronic acid to lengthen the effect of wrinkle-reducing toxins, while the Japanese line relies on glycerin, which clinical study findings show significantly improved stratum corneum hydration.
Good Molecules is an American skincare brand founded in 2019 and owned by Beautylish, Inc..
beautymatter.comgoodmolecules.compitchbook.compreqin.com
Shiseido is a Japanese skincare brand founded in 1872 and owned by Shiseido Company, Limited.
corp.shiseido.comen.wikipedia.orgmarketscreener.com
This page compares some of the most popular Good Molecules and Shiseido products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Good Molecules vs Shiseido products
People Say
Deep hydration and moisture Often MentionedMostly Mentioned
- “Immediate sensation of comfort — Shiseido Benefiance Wrinkle Smoothing Eye Cream”
- “skin feels plump, soft and nourished, eliminates dryness, bouncy feel — Shiseido VITAL PERFECTION”
- “Skin feels more hydrated — Shiseido Activating Essence”
- “skin appears smooth and supple — Good Molecules Hyaluronic Acid Serum”
Affordable price and great value Mostly MentionedNot noted
- “best value for money — Good Molecules Hyaluronic Acid Serum”
- “great value — Good Molecules Niacinamide Serum”
Luxurious and elegant texture Sometimes NotedOften Mentioned
- “silky smooth, rich but non-greasy, absorbs quickly, melts into skin — Shiseido VITAL PERFECTION”
- “Velvety, rich cream texture — Shiseido Benefiance Wrinkle Smoothing Eye Cream”
- “Velvety texture — Shiseido FUTURE SOLUTION LX”
- “absorbs almost instantly — Good Molecules Hyaluronic Acid Serum”
Brightening and radiant glow Sometimes NotedOften Mentioned
- “Skin looks brighter, more radiant, and "glowy." — Shiseido Ultimune Power Infusing Concentrate”
- “faded pimple marks — Shiseido White Lucent Brightening Gel Cream”
- “Eyes look more awake — Shiseido Benefiance Wrinkle Smoothing Eye Cream”
- “skin looks more radiant — Good Molecules Niacinamide Brightening Toner”
Improves skin texture and smoothness Often MentionedSometimes Noted
- “skin looks like brand new baby skin — Good Molecules Overnight Exfoliating Treatment”
- “Leaves skin "baby soft," "super smooth," "polished feel" — Good Molecules Pineapple Exfoliating Powder”
- “softened fine lines — Good Molecules Gentle Retinol Cream”
- “makes skin baby soft — Shiseido Benefiance Wrinkle Smoothing Cream Enriched”
Lightweight and non-greasy texture Sometimes NotedSometimes Noted
- “absorbs quickly... zero irritation or tacky feeling — Good Molecules Discoloration Correcting Serum”
- “absorbs instantly into skin — Good Molecules Lightweight Daily Moisturizer”
- “Airy-soft texture — Shiseido Essential Energy Hydrating Cream”
- “absorbs quickly — Shiseido White Lucent Brightening Gel Cream”
High price point Not notedMostly Mentioned
- “Very expensive for the size — Shiseido Benefiance Wrinkle Smoothing Eye Cream”
Strong fragrance and scent complaints Sometimes NotedOften Mentioned
- “Strong bergamot smell — Good Molecules Super Peptide Serum”
- “weird faint smell — Good Molecules Gentle Retinol Cream”
- “smelled of glycolic acid — Good Molecules Overnight Exfoliating Treatment”
- “old lady smell — Shiseido Eudermine Revitalizing Essence”
Packaging issues and design Sometimes NotedSometimes Noted
- “Metal tube cracks — Good Molecules Yerba Mate Wake Up Eye Gel”
- “Hole is too big — Good Molecules Pineapple Exfoliating Powder”
- “heavy to travel — Shiseido Eudermine Revitalizing Essence”
- “Heavy bottle but plastic pump, cannot see remaining product, straw too short to get last drops. — Shiseido Ultimune Power Infusing Concentrate”
Good Molecules vs Shiseido routines for dry skin
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Cleanser
CeraVe Hydrating Facial Cleanser
Morning · Evening · Once a week
S$25.06
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Hydrating Toner
COSRX Propolis Synergy Toner
Morning
S$41.07
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Moisturizer
d'Alba First Spray Serum
Morning · Evening · Once a week
S$25.94
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SPF
thinkbaby Safe Sunscreen SPF 50+
Morning
S$21.09
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Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
S$39.68
-
Serum or Treatment
Discoloration Correcting Serum
Evening · Once a week
S$56.22
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Nourishing Mask
MEDIHEAL Collagen Essential Mask
Once a week
S$62.94
-
Cleanser
Clarifying Cleansing Foam
Morning · Evening · Once a week
S$54.05
-
Hydrating Toner
Eudermine Revitalizing Essence
Morning
S$112.11
-
Moisturizer
Essential Energy Hydrating Cream
Morning · Evening · Once a week
S$78.82
-
SPF
thinkbaby Safe Sunscreen SPF 50+
Morning
S$21.09
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
S$39.68
-
Serum or Treatment
Ultimune Power Infusing Concentrate
Evening · Once a week
S$9.25
-
Nourishing Mask
MEDIHEAL Collagen Essential Mask
Once a week
S$62.94
Buy Good Molecules routine · S$272.00 · 96% fit
Buy Shiseido routine · S$256.58 · 74% fitSee multi-brand routine · 99% fit
Good Molecules vs Shiseido routines for oily skin
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Cleanser
CeraVe Foaming Facial Cleanser
Morning · Evening · Once a week
S$30.40
-
Hydrating Toner
TROIAREUKE H+Cocktail Purifying Ampoule Toner
Morning · Once a week
S$168.51
-
Moisturizer
SKIN1004 Centella Cream
Morning · Evening · Once a week
S$33.87
-
SPF
CeraVe AM Facial Moisturizing Lotion SPF 30
Morning
S$28.72
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
S$70.21
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening · Once a week
S$36.48
-
Serum or Treatment
Overnight Exfoliating Treatment
Evening · Once a week
S$43.99
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
S$89.14
-
Cleanser
Deep Cleansing Foam
Morning · Evening · Once a week
S$52.06
-
Hydrating Toner
Eudermine Revitalizing Essence
Morning · Once a week
S$112.11
-
Moisturizer
Essential Energy Hydrating Cream
Morning · Evening · Once a week
S$78.82
-
SPF
CeraVe AM Facial Moisturizing Lotion SPF 30
Morning
S$28.72
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
S$70.21
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening · Once a week
S$36.48
-
Serum or Treatment
Ultimune Power Infusing Concentrate
Evening · Once a week
S$9.25
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
S$89.14
Buy Good Molecules routine · S$501.32 · 96% fit
Buy Shiseido routine · S$355.43 · 82% fitSee multi-brand routine · 96% fit
Good Molecules vs Shiseido routines for combination skin
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Cleanser
Fresh Soy Face Cleanser
Morning · Evening · Once a week
S$30.00
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Hydrating Toner
Whamisa Organic Flowers Toner Deep Rich
Morning · Once a week
S$64.81
-
SPF
CeraVe AM Facial Moisturizing Lotion SPF 30
Morning
S$28.72
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
S$70.21
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening · Once a week
S$36.48
-
Serum or Treatment
Overnight Exfoliating Treatment
Evening · Once a week
S$43.99
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
S$89.14
-
Cleanser
Deep Cleansing Foam
Morning · Evening · Once a week
S$52.06
-
Hydrating Toner
Eudermine Revitalizing Essence
Morning · Once a week
S$112.11
-
Moisturizer
Essential Energy Hydrating Cream
Morning · Evening · Once a week
S$78.82
-
SPF
CeraVe AM Facial Moisturizing Lotion SPF 30
Morning
S$28.72
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
S$70.21
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening · Once a week
S$36.48
-
Serum or Treatment
Ultimune Power Infusing Concentrate
Evening · Once a week
S$9.25
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
S$89.14
Buy Good Molecules routine · S$363.35 · 97% fit
Buy Shiseido routine · S$355.43 · 82% fitSee multi-brand routine · 97% fit
Questions and answers
Good Molecules or Shiseido: which is better?
Good Molecules offers better value with more affordable prices and fragrance-free formulas, while Shiseido provides more luxurious textures and deep hydration. For dry skin routines, Lovi rates Good Molecules as Superior and Shiseido as Average.
What is the difference between Good Molecules and Shiseido?
Good Molecules offers a more affordable price point and great value, while Shiseido provides deep hydration and luxurious textures. Good Molecules also stands out for its fragrance-free formulas, as every product on this page lists no fragrance, whereas 15 of Shiseido's 20 products contain fragrance.
Good Molecules or Shiseido for dry skin?
Good Molecules is the better choice for dry skin, as Lovi rates its routine fit as Superior compared to Shiseido's Average. Good Molecules offers deeply hydrating and affordable moisturizers and serums that help nourish dry skin effectively.
Good Molecules or Shiseido: which cleanser is better?
Good Molecules is the better choice for cleansers because Lovi rates its Hydrating Facial Cleansing Gel as High for dry and sensitive skin, whereas Shiseido cleansers range from Low to Caution for those skin types.
Which is more affordable, Good Molecules or Shiseido?
Good Molecules is more affordable, as reviewers mention it offers affordable and great value serums and moisturizers. In contrast, reviewers note that Shiseido has a high price point.
Which brand has products that are entirely free of fragrance according to the ingredients lists?
Good Molecules has products that are entirely free of fragrance on this page, as every single item lists no fragrance in its ingredients.
How do the founding years and countries of origin compare between Good Molecules and Shiseido?
Good Molecules was founded in the United States in 2019, whereas Shiseido is a much older brand founded in Japan in 1872.
Which brand performs better for providing deep hydration and moisture according to review themes?
Shiseido performs better for providing deep hydration and moisture according to the review themes.
Good Molecules or Shiseido for oily skin?
Good Molecules is a Superior fit for oily skin, whereas Shiseido is a High fit. Reviewers note that Good Molecules offers affordable and great value serums, while Shiseido products often feature strong fragrances.
Good Molecules or Shiseido: which moisturizer is better?
Good Molecules is better for moisturizers because it offers affordable and hydrating options with zero fragrance across its products. Reviewers highlight Good Molecules for its affordable price and great value, whereas Shiseido is often noted for a high price point and strong fragrance complaints.
Good Molecules or Shiseido for sensitive skin?
Good Molecules is a better fit for sensitive skin, offering a Superior routine fit compared to Shiseido's High fit on this page. Good Molecules also has the advantage of listing no fragrance across its products.
Good Molecules or Shiseido: which sunscreen is better?
Good Molecules offers a superior fit for dry sensitive skin, dry skin, sensitive skin, skin with dark spots, and mature skin with its Sheer Mineral Sunscreen SPF 30. In contrast, Shiseido features options like the Benefiance Wrinkle Smoothing Day Cream and Essential Energy Hydrating Day Cream, though reviewers frequently mention a strong fragrance.
Good Molecules or Shiseido for acne-prone skin?
Good Molecules has a Superior routine fit for acne-prone skin, while Shiseido has a High routine fit. Reviewers mention that Good Molecules offers very gentle serums, though some note occasional breakouts.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Psychophysical study of the effects of topical application of menthol in healthy volunteers
Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling
Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine
Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant
Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil
Chemical peels for acne vulgaris: a systematic review of randomised controlled trials
In vivo and in vitro evaluation of octyl methoxycinnamate liposomes
Anatomical site differences of sodium lauryl sulfate-induced irritation: randomized controlled trial
Skin recovery by Lavandula angustifolia leaf callus extract: Redox control of Nrf2 signaling
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects
Development and efficacy assessments of tea seed oil makeup remover
Functional properties and skin care effects of sodium trehalose sulfate
Transdermal Delivery of Baicalin Based on Bio-Vesicles and Its Efficacy in Antiaging of the Skin
Liposomal formulation of a vitamin C derivative: a promising strategy to increase skin permeability
Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin
New Chalcone-Derived Molecule for the Topical Regulation of Hyperpigmentation and Skin Aging
Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism
Retrospective Review of Dermal Safety Studies of Organic Sunscreens
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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