Medik8 Liquid Peptides for sensitive skin
Acetyl Hexapeptide-8
Palmitoyl Tripeptide-1
Palmitoyl Tetrapeptide-7
Average
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
Works for sensitive skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Suitable for normal skin, this formula contains Glycerin and Hyaluronic Acid to support hydration without causing irritation, aligning with your skin type and sensitivity.
- The presence of Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1 offers moderate plumping benefits, contributing to skin volume and elasticity.
- The product is safe for your sensitive skin as it lacks harsh or prohibited ingredients, ensuring no risks of irritation.
How to apply
- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
People Say
★4.6Overall rating based on 200+ reviewsUsers consistently praise this serum as a "Botox in a bottle" alternative that delivers immediate hydration and visible plumping, particularly for fine lines on the forehead and around the eyes. It is widely celebrated for its ability to smooth skin texture and restore bounce to dry or mature skin without causing irritation, making it a staple for those targeting early to advanced signs of aging.
Highlights
Deeply hydrating Mostly Mentioned
- “Restores moisture”
- “Eliminates dry patches”
- “Leaves skin dewy”
- “'Glass skin' finish”
Elegant, lightweight texture Often Mentioned
- “Absorbs fast”
- “Non-greasy”
- “Silky feel”
- “Layers perfectly under makeup/SPF”
Visibly plumps and smooths Often Mentioned
- “Reduces fine lines”
- “Softens expression lines”
- “'Botox-like' effect”
- “Improves skin bounce”
High price point Often Mentioned
- “Expensive per bottle”
- “Investment skincare”
- “Pricey for the size”
- “Waiting for sales”
Gentle and non-irritating Sometimes Noted
- “Suitable for sensitive skin”
- “No stinging”
- “Works with retinol”
- “Calms redness”
Packaging fragility Sometimes Noted
- “Glass bottle breaks easily”
- “Dropper issues”
- “Difficult to get last drops”
- “Travel concerns”
Results require patience Rarely Noted
- “Subtle initial changes”
- “Takes weeks for deep wrinkles”
- “Not a 'miracle' for everyone”
Slight tackiness Rarely Noted
- “Can feel sticky if over-applied”
- “Needs time to dry”
- “'Glue-like' texture for some”
Sources: lovi.care, dermstore.com, cultbeauty.com, spacenk.com, medik8.com, amazon.com, and more
Questions and answers
How well does Medik8 Liquid Peptides work for sensitive skin?
Medik8 Liquid Peptides works for sensitive skin, though other treatments fit it better. It contains glycerin and hyaluronic acid to help keep skin hydrated, along with peptides that may give moderate plumping benefits. Treatments that fit sensitive skin better need soothing ingredients that calm redness and irritation while keeping the skin barrier healthy.
Which ingredients make this serum a good fit for sensitive skin?
Glycerin and Hyaluronic Acid help support hydration without causing irritation, making this serum a workable fit for sensitive skin. To fit sensitive skin even better, a treatment of this type needs effective ingredients that soothe redness and irritation while remaining highly compatible.
What does Argireline do for sensitive skin?
Argireline is unlikely to cause irritation and is sometimes found in products designed to calm reactive skin. Studies show it helps smooth the look of wrinkles and decrease skin roughness when used consistently.
American Journal of Clinical Dermatology, 2013Pharmaceuticals, 2021
What does Palmitoyl Tripeptide-1 do for sensitive skin?
Palmitoyl tripeptide-1 helps smooth fine lines and improves firmness in sensitive skin. It works by supporting collagen levels to keep skin looking youthful and resilient.
Journal of Cosmetic Dermatology, 2026International Journal of Cosmetic Science, 2026
Where does it go in a skincare routine for sensitive skin?
This treatment goes in the evening routine for sensitive skin. It is safe for this skin type and is unlikely to cause irritation, though other products fit sensitive skin better by featuring extra calming and barrier-repairing ingredients.
Can I use this serum with retinol, and in what order?
Yes, you can use this treatment with retinol by applying your retinol product first and following with this serum. This approach helps keep your sensitive skin hydrated with glycerin and hyaluronic acid while minimizing any risk of irritation. For this skin type, a product of this type needs calming agents and gentle hydrators to support the skin barrier effectively.
How often should I use it?
Use this treatment in the evening as part of your routine to keep things simple and safe around sun exposure. A product of this type needs soothing ingredients like glycerin and hyaluronic acid to support hydration without causing irritation for your sensitive skin.
Can this serum clog pores, cause breakouts or purging for sensitive skin?
This serum is unlikely to clog pores or cause breakouts for sensitive skin because it lacks harsh ingredients and relies on hydrating components like glycerin and hyaluronic acid. Products of this type for sensitive skin need gentle hydrators and soothing agents that support moisture without causing irritation.
Is it fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.
Journal of Cosmetic Dermatology, 2026A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.
Journal of Cosmetic Dermatology, 2015Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days.
Annals of Dermatology, 2019Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group.
American Journal of Clinical Dermatology, 2013Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear.
Journal of Cosmetic Dermatology, 2017Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.
International Journal of Cosmetic Science, 2026
Ingredients
Water, Glycerin, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Carbomer, Phenoxyethanol, Ethylhexylglycerin, Hyaluronic Acid, Lecithin, Caprylyl Glycol, Disodium Edta, Citric Acid
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
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Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Specialist dermatologist, MBBS, MD, IFAAD
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Dermatology MD
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Elina Nazarenko, MD
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Dermatology and diagnostic consultant
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Victoria Derkova, MS
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Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.