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Medik8 vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Medik8 and Sesderma are accomplished skincare brands that offer serums, moisturizers, eye products, toners, and advanced formulas. The British brand founded in 2009 features hyaluronic acid to lengthen the toxin wrinkle effect duration, suiting dry skin and dry sensitive skin best with highlights like Surface Radiance Cleanse, Oxy-R Peptides, and Total Moisture Daily Facial Cream. Meanwhile, the Spanish brand founded in 1989 utilizes botanical extracts and active compounds to suit sensitive, hyperpigmented, and aging skin types, featuring standout options such as the Azelac RU Serum. Ultimately, both differ through their distinct heritage, proprietary ingredients, and tailored solutions for specific dermatological concerns.

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

loreal.commedik8.comtracxn.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Medik8 and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Medik8 vs Sesderma products

Medik8 vs Sesderma serums and treatments

Questions and answers

Medik8 or Sesderma: which is better?

Medik8 is the better choice for most shoppers on this page, as it offers a wide range of serums and moisturizers with high Lovi fit levels for dry and sensitive skin. Sesderma has only one product listed here, Azelac RU Serum, which contains fragrance and shows lower fit levels for dry skin.

What is the difference between Medik8 and Sesderma?

Medik8 is a UK-based brand founded in 2009 with a wide range of serums, moisturizers, and cleansers that feature hyaluronic acid and fit dry skin best, whereas Sesderma is a Spanish brand founded in 1989 with only the Azelac RU Serum shown on this page.

Which is more affordable, Medik8 or Sesderma?

The products on this page from Medik8 have reviews noting a high price point as a negative aspect, while the page contains no price or affordability reviews for Sesderma.

Which causes fewer breakouts, Medik8 or Sesderma?

Medik8 is unlikely to cause breakouts, as the products on this page feature gentle, non-irritating formulas that fit acne-prone skin well, whereas Sesderma is represented by a single serum that lacks broad data for breakouts.

How does the country of origin and founding year compare between Medik8 and Sesderma?

Medik8 was founded in the United Kingdom in 2009, whereas Sesderma was founded in Spain in 1989.

Which brand offers a greater variety of products for dry skin according to the Lovi fit levels?

Medik8 offers a much greater variety of products for dry skin on this page, with multiple options achieving Superior and High Lovi fit levels like Bakuchiol Peptides and Hydr8 B5 Intense, whereas Sesderma only features Azelac RU Serum which has a Low fit for dry skin.

How do Medik8 and Sesderma differ in terms of product fragrance formulations?

Medik8 stands out because almost all of the products on this page list no fragrance, whereas Sesderma includes fragrance in its offering. Specifically, Medik8 has 11 out of 12 fragrance-free products, while Sesderma includes fragrance in its Azelac RU Serum.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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