COSRX The Niacinamide 15 Serum for combination skin
Niacinamide
Acetyl Glucosamine
Zinc Pca
Trehalose
AllantoinAverage
- HighCombination Skin Fit
- HighEffectiveness
- ExcellentSafety
Works for combination skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate benefits for your combination skin, as niacinamide and zinc PCA help regulate sebum production and reduce acne lesions, addressing your oily shine concerns.
- Allantoin and trehalose provide additional soothing and hydrating effects, supporting overall skin comfort.
- The formula is safe for your skin, with no harsh ingredients and a good profile for combination skin.
How to apply
- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
People Say
★4.5Overall rating based on 3.1k+ reviewsThis serum is widely praised by users with oily and acne-prone skin for its ability to significantly control sebum and refine pore texture, often delivering a smoother, "glass skin" finish. The high 15% concentration is effective for many, but frequently causes irritation, stinging, or barrier damage for those with sensitive or dry skin types. This summary is based on a very large amount of data and should be definitely taken into account.
Highlights
Controls excess oil Mostly Mentioned
- “less oily T-zone”
- “regulated sebum production”
- “kept oil at bay”
- “balanced my skin”
- “matte but glowing”
Lightweight absorption Often Mentioned
- “absorbs instantly”
- “non-sticky finish”
- “lightweight consistency”
- “layers well”
- “watery and fresh”
Reduces pore visibility Often Mentioned
- “pores look smaller”
- “tightened my pores”
- “pores less visible”
- “refined pore texture”
- “shrunk enlarged pores”
Smoothes skin texture Often Mentioned
- “skin feels softer”
- “bumpy texture gone”
- “smooths rough skin”
- “glass skin effect”
- “improved skin surface”
Fades acne marks Sometimes Noted
- “lightened dark spots”
- “faded post-acne marks”
- “helped with hyperpigmentation”
- “scars are lighter”
- “evened skin tone”
Causes irritation Sometimes Noted
- “stinging sensation”
- “face turned red”
- “burning on application”
- “itchy skin”
- “sensitized my face”
Too strong Sometimes Noted
- “15% is too harsh”
- “damaged skin barrier”
- “too potent for me”
- “over-exfoliated feeling”
- “strong chemical reaction”
Drying effect Rarely Noted
- “dried out my skin”
- “caused flaky patches”
- “skin felt tight”
- “not moisturizing enough”
- “sucked moisture out”
Induces breakouts Rarely Noted
- “caused whiteheads”
- “broke me out”
- “tiny bumps appeared”
- “worsened my acne”
- “clogged my pores”
Sources: lovi.care, ulta.com, iherb.com, sokoglam.com, yesstyle.com, skinsort.com, and more
Questions and answers
How well does COSRX The Niacinamide 15 Serum work for combination skin?
COSRX The Niacinamide 15 Serum offers moderate benefits for combination skin, as ingredients like niacinamide and zinc PCA help control oily shine and soothe the skin. To work best for this skin type, a treatment needs effective ingredients like niacinamide and propolis that provide balanced hydration and radiance without causing excess oiliness or dryness.
The Journal of Clinical and Aesthetic Dermatology, 2020Skin Research and Technology, 2024
Which ingredients make this serum a good fit for combination skin?
This serum works for combination skin because niacinamide and zinc PCA help control oily shine, while allantoin and trehalose soothe and calm dry areas. To be an even better fit for this skin, a treatment of this type needs ingredients like propolis to enhance radiance and provide balanced hydration without excess oiliness.
The Journal of Clinical and Aesthetic Dermatology, 2020Skin Research and Technology, 2024
What does Niacinamide do for combination skin?
Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
What does Acetyl Glucosamine do for combination skin?
Acetyl Glucosamine helps keep combination skin hydrated and smooth while evening out dark spots and patchiness. It also increases water content and supports skin renewal, making dry areas feel soft and oily zones balanced.
Journal of Cosmetic Dermatology, 2007The British Journal of Dermatology, 2010
Where does this serum go in a skincare routine for combination skin?
This serum goes in your evening routine after cleansing and toning, and before moisturizing. Combination skin works best with products that balance oily shine with lightweight soothing ingredients and gentle hydration.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol by applying the serum first in your evening routine, as the formula is safe and gentle on combination skin. Layering it beneath a retinoid treatment may help soothe the skin and reduce irritation while supporting overall comfort.
How often should I use this serum?
You can use this serum in your evening routine, as treatments fit well there for simplicity and extra safety around sun exposure. Combination skin generally benefits from a serum that balances oil production while keeping dry areas calm and hydrated with ingredients like niacinamide, zinc PCA, allantoin, and trehalose.
The Journal of Clinical and Aesthetic Dermatology, 2020Skin Research and Technology, 2024
Can this serum clog pores, cause breakouts or purging for combination skin?
This serum is unlikely to clog pores or cause breakouts for combination skin, as it contains niacinamide and zinc PCA to help regulate oil and keep skin clear. However, reviewers sometimes report mild irritation or breakouts because the strength of the formula may feel too strong for some. A product for this skin needs balancing ingredients that control shine while keeping hydration gentle.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris.
The Journal of Clinical and Aesthetic Dermatology, 2020Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo.
Skin Research and Technology, 2024A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020Topical treatment with Thealoz Duo significantly improved dry eye disease symptoms, tear break-up time, and restored tear lipid layer functionality by reducing inflammatory response proteins in moderate to severe dry eye patients over 56 days.
Journal of Clinical Medicine, 2025Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide.
Journal of Cosmetic Dermatology, 2007N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers.
Advanced Pharmaceutical Bulletin, 2016Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants.
Journal of Cosmetic and Laser Therapy, 2019Zinc PCA inhibits UVA-induced matrix metalloproteinase-1 production through suppressed AP-1 activation and enhances type I collagen synthesis by increasing SVCT2 mRNA expression in cultured normal human dermal fibroblasts.
International Journal of Cosmetic Science, 2012Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments.
Journal of Ocular Pharmacology and Therapeutics, 2019An injectable product combining different molecular weights of hyaluronic acid and trehalose reduced CML formation by 45% at baseline and 30% under methylglyoxal-induced stress while preserving cell viability in human skin explants compared to untreated controls.
International Journal of Molecular Sciences, 2025Combining trehalose with dimethyl sulfoxide improves human fetal skin cryopreservation, resulting in 65% membrane integrity and graft performance indistinguishable from fresh unfrozen skin in immunodeficient mice compared to lower integrity with glycerol or dimethyl sulfoxide alone.
Cryobiology, 2002Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.
Aesthetic Plastic Surgery, 2018Prophylactic application of a topical scar gel containing Allium cepae extract, allantoin, and heparin significantly improves patient-assessed scar color, stiffness, and irregularity compared to no treatment in women following a cesarean section.
Journal of Drugs in Dermatology, 2014
Ingredients
Water, Pentylene Glycol, Niacinamide, Butylene Glycol, Acetyl Glucosamine, 1,2-Hexanediol, Zinc Pca, Trehalose, Hydrolyzed Sclerotium Gum, Pullulan, Allantoin, Ethylhexylglycerin, Sodium Phytate, Tocopherol, Xanthan Gum, Citric Acid
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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