Estée Lauder Futurist Peptide-Power Serum Primer for dry sensitive skin
Acetyl Hexapeptide-8
Palmitoyl Hexapeptide-12
Sodium Hyaluronate
Glycerin
Tetrahexyldecyl Ascorbate
High
- HighDry Skin Fit
- HighEffectiveness
- HighSafety
One of the best moisturizers for dry sensitive skin.
This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your dry and sensitive skin, this serum primer effectively hydrates and plumps with Acetyl Hexapeptide-8 and Sodium Hyaluronate, while whey protein and soybean protein support your skin barrier.
- The inclusion of glycerin and Sodium PCA further enhances its humectant properties, addressing your dry or flaky skin concerns.
- The formulation is safe for your skin, containing no harsh ingredients and featuring soothing components like sodium hyaluronate and whey lactis protein.
How to apply
- Could be used as part of your AM or PM routine. Start using this moisturizer 3 times a week and move to daily use if your dry skin tolerates it well.
- Apply this moisturizer after cleansing and toner in the morning, or after your serum in the evening. Always pair it with SPF in the morning.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it harshly to protect your sensitive skin.
- Apply the moisturizer on slightly damp skin to help with hydration absorption. This also works well for dry and flaky skin types.
- Do a patch test before your first use. Avoid the eye area to prevent any irritation.
People Say
★4.1Overall rating based on 200+ reviewsThis serum-gel primer is highly praised for its hydrating, plumping, and smoothing effects, making it an excellent choice for mature skin or those seeking a radiant, dewy finish. While it excels at creating a smooth, makeup-ready canvas, some users find the packaging frustrating and the price point high for the amount of product provided.
Highlights
Intense hydration Often Mentioned
- “Skin feels more hydrated than it does with the Advanced Night Repair serum.”
- “Maintains its hydration... even in dry conditions.”
- “Provides intense and lasting hydration.”
Radiant finish Often Mentioned
- “Imparts a subtle, healthy sheen that isn't overly oily.”
- “Gives off... just the right amount to make your complexion look fresh and healthy.”
- “Luminous finish.”
Makeup-gripping base Sometimes Noted
- “Creates a beautiful makeup-gripping base.”
- “Preps it perfectly for makeup.”
- “Helps makeup stay in place for longer.”
Smooths fine lines Sometimes Noted
- “Fine lines around my eyes and forehead looked a bit softer.”
- “Reduces the look of fine lines and wrinkles in just 4 weeks.”
- “Smooths the look of fine lines and wrinkles.”
High price/value Sometimes Noted
- “The price is a little steep.”
- “Bottle is just not a good value, it is barely filled.”
- “There are other options that deliver similar results without the luxury price tag.”
Poor packaging Sometimes Noted
- “The dropper is glass... it had cracked from use.”
- “Packaging is also disappointing and feels less refined.”
- “I don't know why it's not in a squeeze tube.”
Heavy/comedogenic concerns Rarely Noted
- “This primer feels quite heavy.”
- “May contain ingredients that could be comedogenic for some skin types.”
Sources: lovi.care, johnlewis.com, macys.com, esteelauder.com, youtube.com, saveozo.com, and more
Questions and answers
What makes Estée Lauder Futurist Peptide-Power Serum Primer a great fit for dry sensitive skin?
This serum primer is a great fit because it helps deeply hydrate and plump dry skin using sodium hyaluronate and glycerin, while supporting your skin barrier with gentle proteins and peptides. It is very safe for sensitive skin, lacking harsh ingredients and utilizing soothing components.
Clinical, Cosmetic and Investigational Dermatology, 2017Annals of Dermatology, 2019
Which ingredients make this serum a good fit for dry sensitive skin?
This serum is a great fit for dry sensitive skin because it uses sodium hyaluronate and glycerin to draw in moisture, alongside soothing proteins that help keep your skin barrier comfortable and calm. It also includes peptides that help smooth out the skin without causing irritation.
What does Argireline do for dry sensitive skin?
Argireline helps smooth fine lines and keeps skin soft, but dry sensitive skin needs added moisture and soothing ingredients to feel fully comfortable. It is unlikely to cause irritation when used as directed, yet a product of this type for dry sensitive skin needs rich hydrators and calming agents to prevent dryness and protect the skin barrier.
American Journal of Clinical Dermatology, 2013International Journal of Molecular Sciences, 2025
What does Palmitoyl Hexapeptide-12 do for dry sensitive skin?
Palmitoyl hexapeptide-12 helps repair and strengthen the skin barrier for dry sensitive skin. It penetrates the outer layers of the skin to support hydration and improve comfort.
Where does this serum go in a skincare routine for dry sensitive skin?
This treatment goes in the evening routine after your cleansing and toning steps, before your moisturizer. Putting treatments in the evening helps keep things simple and provides extra safety around sun exposure.
Can I use this serum with retinol, and in what order?
You can use this serum primer alongside retinol by applying the serum first to hydrate and soothe your skin before layering retinol on top. This approach helps maintain your skin barrier and is unlikely to cause irritation when using strong active ingredients.
How often should I use this serum?
You can use this treatment in the evening as part of your routine. Daily application is unlikely to irritate dry sensitive skin and helps keep it soft and hydrated.
Can this serum clog pores, cause breakouts or purging for dry sensitive skin?
This serum primer is unlikely to clog pores or cause breakouts for dry sensitive skin, as reviewers rarely report heavy or pore-clogging concerns. Its gentle formula hydrates without harsh ingredients, making it safe for delicate skin.
Can I use this serum around the eyes or on my body?
This serum primer is safe to use around the eyes because its gentle formula features soothing components and lacks harsh ingredients that could upset delicate areas. Clinical studies show that moisturizing ingredients like hyaluronic acid and glycerin help smooth fine lines and boost hydration in the eye area with very good skin tolerance.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days.
Annals of Dermatology, 2019Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear.
Journal of Cosmetic Dermatology, 2017A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group.
American Journal of Clinical Dermatology, 2013Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy.
European Journal of Neurology, 2013Argireline applied twice daily for 4 weeks achieved a total anti-wrinkle efficiency of 48.9% and notably reduced wrinkle depth compared to placebo in Chinese subjects.
Journal of Cosmetic and Laser Therapy, 2013A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.
Journal of Cosmetic Dermatology, 2015Palmitoyl hexapeptide-12 permeates the stratum corneum and epidermis, initiating gel formation via endogenous ions and strengthening and repairing the skin barrier after delipidation in human skin.
ACS Applied Bio Materials, 2025Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022
Ingredients
Water, Butylene Glycol, Glycerin, Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-12, Sodium Pca, Whey Lactis Proteine Du Petit-Lait Protein, Glycine Soja Protein Soybean Protein, Sodium Hyaluronate, Acetyl Glucosamine, Lactobacillus Ferment, Tetrahexyldecyl Ascorbate, Chlorella Vulgaris Extract, Algae Extract, Caprylyl Glycol, Caffeine, Hydrolyzed Rice Extract, Laminaria Digitata Extract, Glucose, Artemia Extract, Sucrose, Peg-8, Xanthan Gum, Sodium Polyacryloyldimethyl Taurate, Calcium Chloride, Glyceryl Polymethacrylate, Sodium Hydroxide, Propanediol, Bht, Tocopheryl Acetate, Disodium Edta, Silica, Phenoxyethanol, Potassium Sorbate, Chlorphenesin, Mica, Titanium Dioxide Ci 77891, Iron Oxides Ci 77492, Bismuth Oxychloride, Carmine
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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