Estée Lauder Advanced Night Repair Eye Supercharged Gel-Creme for dry sensitive skin

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo.

  Skin Research and Technology, 2024

• Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.

  Journal of Cosmetic Dermatology, 2023

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• A topical cosmetic slimming product containing tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol significantly reduced body circumferences and improved skin aspect compared with placebo in 78 women over 12 weeks.

  International Journal of Cosmetic Science, 2011

• Topical sunscreen formulations containing caffeine combined with UV filters increased in vivo anti-UVB protection by approximately 25% and showed higher SPF values compared to caffeine-free sunscreen, while being well tolerated by the skin of healthy subjects.

  Frontiers in Physiology, 2019

• Caffeine gel combined with choline geranate showed high skin permeation capacity and superior clinical results in cellulite treatment compared to caffeine gel without ionic liquid.

  AAPS PharmSciTech, 2021

• Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

  Molecules, 2025

• Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

  Antioxidants, 2025

Ingredients

Water, Dimethicone, Methyl Trimethicone, Bifida Lysate Ferment, Dimethicone Vinyl Dimethicone Crosspolymer, Propanediol, Petrolatum, Sucrose, Glycerin, Butylene Glycol, Acrylamide Sodium Acryloyldimethyltaurate Copolymer, Trehalose, Tripeptide-32, Adansonia Digitata Seed Extract, Lavandula Angustifolia Flower Extract Lavender Flower Extract, Sodium Hyaluronate, Lactobacillus Ferment, Tocopheryl Acetate, Yeast Extract, Hypnea Musciformis Extract, Sodium Rna, Caffeine, Squalane, Anthemis Nobilis Oil Flower, Poria Cocos Sclerotium Extract, Watermelon Fruit Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Ethylhexylglycerin, Sodium Pca, Phytosphingosine, Hydrolyzed Algin, Hordeum Distichon Extract Hordeum Vulgare Extract, Jojoba Esters, Wheat Germ Oil, Hydrogenated Lecithin, Lecithin, Isohexadecane, Jojoba Alcohol, Isopropyl Jojobate, Peg Ppg-18 18 Dimethicone, Polysorbate 80, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Sorbitan Oleate, Sodium Lactate, Polysorbate 40, Potassium Gluconate, Tocopherol, Bht, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate, Iron Oxides Ci 77491, Iron Oxides Ci 77492

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.