COSRX The Hyaluronic Acid 3 Serum for mature skin

How to apply

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

  Journal of Drugs in Dermatology, 2012

• Topical dry mouth products containing olive oil, betaine, and xylitol significantly increased unstimulated whole salivary flow rates, reduced xerostomia complaints, and improved quality of life in adults with polypharmacy-induced xerostomia compared to their normal routine care, with no clinically significant adverse events.

  Journal of Oral Rehabilitation, 2007

• Soaps containing betaine caused the least skin irritation compared to other tested soaps in twenty-eight healthy subjects, though irritation did not decrease with increasing concentrations of betaine.

  Skin Research and Technology, 2003

• A combination of Aloe barbadensis leaf extract and trimethylglycine in a 1:1 mass ratio synergistically increased aquaporin 3 expression by up to 380% in keratinocytes and safely improved skin hydration in healthy volunteers.

  Molecules, 2024

Why other moisturizers fit mature skin better

• Daily consumption of fermented pomegranate extract drinks and serums improved skin moisture, brightness, elasticity, and collagen density while reducing spots in healthy subjects compared to baseline.

  Journal of Cosmetic Dermatology, 2022

• Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo.

  Skin Research and Technology, 2024

• Aged Punica granatum extract significantly reduced UV-induced erythema and melanin levels while improving skin hydration and lightness compared to placebo in 60 women.

  Food Science & Nutrition, 2025

Ingredients

Water, Butylene Glycol, Propanediol, Glycerin, Sodium Hyaluronate, Pentylene Glycol, 1,2-Hexanediol, Diethoxyethyl Succinate, Sodium Polyacryloyldimethyl Taurate, Betaine, Xanthan Gum, Dimethicone, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Sodium Pca, Sodium Lactate, Pca, Glyceryl Acrylate Acrylic Acid Copolymer, Hydrogenated Lecithin, Ethylhexylglycerin, Serine, Alanine, Glycine, Sodium Phytate, Sorbitan Isostearate, Pvm Ma Copolymer, Glutamic Acid, Citric Acid, Lysine Hcl, Threonine, Arginine, Sodium Methyl Stearoyl Taurate, Proline, Ceramide Np, Cholesterol, Caprylic Capric Triglyceride, Phytosphingosine, Stearic Acid, Oleic Acid, Alcohol, Tocopherol, Lactic Acid, Caprylyl Glycol, Caprylhydroxamic Acid

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.