Hexapeptide and lactic acid
Keep them apart
Apply lactic acid and hexapeptide at different times of day because acids break down peptides and ruin their anti-aging power. The acidic lactic acid destroys the delicate structure of the hexapeptide, stopping it from smoothing your skin. You can use one in the morning and the other at night, or use milder formulas.
Hexapeptide products
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SkinCeuticals
P-TOX
SAR 733.61
Lactic acid products
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Medicube
Zero Pore Pad
SAR 64.80
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First Aid Beauty
KP Bump Eraser Body Scrub
SAR 107.07
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EltaMD
UV Clear Broad-Spectrum SPF 46
SAR 125.78
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First Aid Beauty
Facial Radiance Pads
SAR 129.00
- CeraVe SA Lotion for Rough & Bumpy Skin
- CeraVe Renewing SA Cream
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The Ordinary
Alpha Arbutin 2% + HA
SAR 63.55
- The Ordinary Retinal 0.2% Emulsion
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Kate Somerville
ExfoliKate Intensive Exfoliating Treatment
SAR 148.70
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Dr. Dennis Gross
Alpha Beta Universal Daily Peel
SAR 317.82
- The Ordinary Lactic Acid 5% + HA
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Good Molecules
Overnight Exfoliating Treatment
SAR 77.61
Questions and answers
Can you use hexapeptide and lactic acid together?
No, keep hexapeptide and lactic acid apart in your routine because the low pH of lactic acid may break down the peptide bonds and reduce its effectiveness. Instead, use them in separate steps or routines, such as applying one in the morning and the other at night.
Which goes first, hexapeptide or lactic acid?
Keep hexapeptide and lactic acid apart by using them in separate steps or routines, such as AM and PM separation. The low pH of lactic acid may destabilize the peptide bonds and reduce the bioactivity of hexapeptide.
Are hexapeptide and lactic acid good for sensitive skin?
Hexapeptide and lactic acid should be separated into different routines to protect sensitive skin because the low pH of lactic acid may destabilize peptides and reduce their effectiveness.
Research on hexapeptide and lactic acid
Behind this pairing advice
Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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