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Bioderma vs Sesderma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Bioderma and Sesderma are European skincare companies that offer targeted treatments for various skin types. The French brand, founded in 1977, provides a thoughtful assortment of moisturizers, makeup removers, serums, and cleansers anchored by nourishing glycerin, suiting dry and sensitive skin best through barrier-respecting formulas. Meanwhile, the Spanish brand, founded in 1989, is beloved for its advanced serums and meticulously engineered formulas featuring botanical extracts and active compounds that suit sensitive, hyperpigmented, and aging skin types. Both entities differ primarily in their origin, key ingredients, and specific product formulations designed to address distinct concerns like acne, dark spots, and maturity.

Bioderma is a French skincare brand founded in 1977 and owned by Jean-Noël Thorel Foundation since 2018.

bioderma.usnaos.com

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

skinexpert.sesderma.comsesderma.com

This page compares some of the most popular Bioderma and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.

Popular Bioderma vs Sesderma products

Questions and answers

Bioderma or Sesderma: which is better?

Bioderma offers a much wider selection of products on this page across multiple categories, whereas Sesderma is represented by only a single serum. Reviewers frequently note that Bioderma provides soothing and barrier-repairing moisturizers as well as gentle, non-irritating cleansers and makeup removers.

What is the difference between Bioderma and Sesderma?

Bioderma is a French brand founded in 1977 that offers a wide range of products with fit levels varying by skin type, while Sesderma is a Spanish brand founded in 1989 with only one product featured on this page, Azelac RU Serum. Bioderma products on this page frequently feature glycerin and golden seaweed, and nearly half contain no fragrance, whereas Azelac RU Serum lists fragrance.

Which is more affordable, Bioderma or Sesderma?

Reviewers note that Bioderma sometimes has high price point and value concerns on the products on this page. Sesderma has no pricing data noted on this page.

Which causes fewer breakouts, Bioderma or Sesderma?

Bioderma offers multiple products on this page with a High Lovi fit for acne-prone skin, such as Sensibio Gel Moussant and Sébium Mat Control, whereas Sesderma features only Azelac RU Serum which has a High fit for acne-prone skin.

When was Bioderma founded compared to Sesderma?

Bioderma was founded in 1977 in France, while Sesderma was founded later in 1989 in Spain.

Which brand offers products with no fragrance, Bioderma or Sesderma?

Bioderma offers products with no fragrance, as 9 of 20 products on this page list no fragrance, whereas Sesderma includes fragrance in its Azelac RU Serum.

In which countries were Bioderma and Sesderma founded?

Bioderma was founded in France, while Sesderma was founded in Spain.

Research behind their key ingredients

Behind this comparison

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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