Bioderma vs Sesderma
Bioderma and Sesderma are respected European skincare houses offering specialized solutions for diverse complexions. The French pioneer, founded in 1977, is known for gentle moisturizers, soothing makeup removers, targeted serums, and purifying cleansers enriched with glycerin, suiting acne-prone and oily skin best through essentials like the Sensibio Gel Moussant, Sensibio Micellar Cleansing Oil, and Atoderm Intensive Eye. Meanwhile, the Spanish creator, established in 1989, is beloved for advanced serums and meticulously engineered formulas featuring botanical extracts and active compounds that best suit sensitive, hyperpigmented, and aging skin types with standout items like the Azelac RU Serum. Ultimately, both brands differ in their geographical origins and founding eras, yet each thoughtfully formulates its offerings to refine texture, promote radiance, and improve hydration.
Bioderma is a French skincare brand founded in 1977 and owned by Jean-Noël Thorel Foundation since 2018.
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
This page compares some of the most popular Bioderma and Sesderma products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Questions and answers
Bioderma or Sesderma: which is better?
Bioderma offers a much wider variety of products across this page with high Lovi fit levels for sensitive and acne-prone skin, whereas Sesderma is represented by only a single serum. Reviewers frequently note that Bioderma's products are effective and soothing, though some mention high prices and occasional texture issues.
What is the difference between Bioderma and Sesderma?
Bioderma offers a wide range of twenty products featuring key ingredients like glycerin and golden seaweed, whereas Sesderma is represented by only one product on this page, Azelac RU Serum. Reviewers frequently note Bioderma for its soothing and barrier-repairing moisturizers as well as gentle makeup removers.
Which is more affordable, Bioderma or Sesderma?
Bioderma offers a wide range of products on this page, but some reviewers note concerns regarding its high price point, whereas Sesderma is represented by only one product here, making direct affordability comparisons difficult.
Which causes fewer breakouts, Bioderma or Sesderma?
Bioderma offers multiple products on this page with a high Lovi fit for acne-prone skin, such as Sébium Mat Control, while Sesderma has only one featured product, Azelac RU Serum, which also achieves a high fit for acne-prone skin.
Which brand has been around longer and in which countries were they founded?
Bioderma has been around longer, having been founded in France in 1977, whereas Sesderma was founded in Spain in 1989.
How many products from Bioderma and Sesderma list fragrance on this page?
On this page, eleven of the twenty Bioderma products and all of the Sesderma products list fragrance.
What are some of the common pros and cons reported by reviewers regarding Bioderma products?
Reviewers of Bioderma products on this page mostly mention soothing and barrier-repairing moisturizers, gentle makeup removers, and effective cleansers. Some note cons such as high price points, texture issues like stickiness, unpleasant fragrances, and that the products can sometimes be drying.
Research behind their key ingredients
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Hesperidin, Hesperetin, Rutinose, and Rhamnose Act as Skin Anti-Aging Agents
Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy
Effect of topically applied lipids on surfactant-irritated skin
Potentially beneficial effects of rhamnose on skin ageing: an in vitro and in vivo study
Formulation strategies to modulate the topical delivery of anti-inflammatory compounds
Salicyloyl-phytosphingosine: a novel agent for the repair of photoaged skin
Interest in Micellar Solution to Reduce Unpleasant Skin Sensations
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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