Some By Mi Snail Truecica Miracle Repair Serum for skin with dark spots

How to apply

Questions and answers

What the research says

• Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer.

  The British Journal of Dermatology, 2002

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.

  Molecules, 2023

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks.

  Journal of Cosmetic Dermatology, 2022

• HelixComplex snail mucus protected human keratinocytes and reconstructed human epidermis models from ozone-induced oxidative damage and pro-inflammatory response following exposure to 0.5 ppm ozone for 2 hours.

  PloS One, 2020

• Topical treatment with Snail Secretion Filtrate significantly improves the speed and percentage of wound area closure, enhances proliferation and tissue remodeling, and reduces inflammation in a full-thickness excisional wound model in mice compared to untreated controls.

  Veterinary Sciences, 2021

• Chitosan-based hydrogels loaded with asiaticoside-rich Centella asiatica extract achieved controlled drug release, skin permeability, antimicrobial activity, and synergistic wound healing effects in an in vitro model.

  International Journal of Molecular Sciences, 2023

• Centella asiatica extract significantly decreased markers of cell death, oxidative stress, cellular senescence, and apoptosis in hydrogen peroxide-induced human epidermal keratinocytes compared to cells treated with hydrogen peroxide alone.

  Biology, 2025

• A topical spray containing Centella asiatica extract was non-irritating and achieved complete wound healing after 14 days in an excision wound rat model.

  Acta Pharmaceutica, 2016

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline.

  Experimental Dermatology, 2008

• Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream.

  International Journal of Cosmetic Science, 2008

• Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.

  Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016

• A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.

  Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020

• An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.

  Aesthetic Plastic Surgery, 2018

Ingredients

Water, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Snail Secretion Filtrate, C12-14 Pareth-12, C12-14 Pareth-7, Carbomer, Tromethamine, Dioscorea Japonica Root Extract, Trehalose, Ethylhexylglycerin, Beta-Glucan, Hydrolyzed Corn Starch, Bergamot Oil Fruit, Allantoin, Adenosine, Disodium Edta, Sucrose, Melaleuca Alternifolia Tree Leaf Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Agrimonia Eupatoria Extract, Salvia Officinalis Oil, Centella Asiatica Extract, Salvia Officinalis Leaf Extract, Camellia Sinensis Leaf Extract, Chamaecyparis Obtusa Leaf Extract, Silybum Marianum Seed Extract, Perilla Frutescens Leaf Extract, Sodium Chondroitin Sulfate, Broussonetia Kazinoki Root Extract, Propolis Extract, Artemisia Capillaris Extract, Cimicifuga Dahurica Root Extract, Willow Bark Extract, Pentylene Glycol, Madecassoside, Oenothera Biennis Flower Extract, Asiaticoside, Asiatic Acid, Madecassic Acid, Phenoxyethanol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.