SKIN1004 Madagascar Centella Probio-cica Intensive Ampoule for sensitive skin
Lactobacillus Centella Asiatica Extract Ferment Filtrate
Ceramide Np
Allantoin
PanthenolSuperior
- SuperiorNormal Skin Fit
- SuperiorEffectiveness
- ExcellentSafety
One of the best serums for sensitive skin.
This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Excellent suitability for your normal skin and goals of reducing redness and irritation is provided by Lactobacillus Centella Asiatica Extract Ferment Filtrate and Centella Asiatica Extract, which offer potent anti-inflammatory and soothing benefits.
- Ceramide NP and Polyhydroxystearic Acid further enhance skin barrier resilience, ensuring your skin remains hydrated and protected.
- The product is safe for your sensitive skin, featuring soothing ingredients like Panthenol and Allantoin with no harsh or irritating components.
How to apply
- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
People Say
★4.8Overall rating based on 3.5k+ reviewsThis ampoule is widely celebrated for repairing damaged skin barriers and soothing irritation, particularly for dry, sensitive, or mature skin types. Users consistently praise its rich, milky texture that provides deep hydration and a radiant glow without a sticky residue. However, it is often deemed too heavy for oily skin or humid weather. This summary is based on a very large amount of data and should be definitely taken into account.
Highlights
Soothing and calming Mostly Mentioned
- “calms redness instantly”
- “comforting hug for angry barrier”
- “redness disappears overnight”
Deeply moisturizing Often Mentioned
- “skin has never felt so hydrated”
- “hydration fiesta”
- “plump and nourish the skin”
- “moisturizing enough to skip cream”
Luxurious texture Often Mentioned
- “milky but non-sticky”
- “absorbs like a dream”
- “smooth and silky finish”
- “leaves skin baby soft”
Barrier repair Sometimes Noted
- “heals moisture barrier faster”
- “restored my damaged barrier”
- “skin feels more resilient”
- “great for retinol users”
Too heavy Sometimes Noted
- “too oily for combo skin”
- “good winter serum, not summer”
- “felt a bit greasy”
- “sat on top of skin”
Caused breakouts Rarely Noted
- “broke me out slightly”
- “caused small whiteheads”
- “clogged my pores”
Dropper issues Rarely Noted
- “dropper takes while to fill”
- “hard to get product out”
- “prefer an airless pump”
- “pipette struggles with thick texture”
Scent concerns Rarely Noted
- “has an earthy scent”
- “subtle botanical aroma”
- “smell is a deal breaker”
- “fermented smell”
Sources: lovi.care, iherb.com, oliveyoung.com, stylevana.com, yesstyle.com, reddit.com, and more
Questions and answers
What makes SKIN1004 Probio-cica Intensive Ampoule one of the best fits for sensitive skin?
This product is an exceptional fit for sensitive skin because it uses fermented centella extract to powerfully calm redness and irritation. Ingredients like ceramide NP and polyhydroxystearic acid help build up your skin barrier so it stays protected, while panthenol and allantoin soothe without any harsh components.
Indian Journal of Pharmaceutical Sciences, 2016American Journal of Clinical Dermatology, 2002
Which ingredients make this ampoule a good fit for sensitive skin?
This ampoule is a great fit for sensitive skin because it features soothing ingredients like Lactobacillus Centella Asiatica Extract Ferment Filtrate, Centella Asiatica Extract, Panthenol, and Allantoin that help reduce redness and irritation. Ceramide NP and Polyhydroxystearic Acid also work to strengthen your skin barrier and keep it protected.
Indian Journal of Pharmaceutical Sciences, 2016American Journal of Clinical Dermatology, 2002
What does Lactobacillus do for sensitive skin?
Lactobacillus helps calm sensitive skin and keeps it comfortable by reducing redness, lowering inflammation, and supporting the skin's moisture barrier. This ingredient may also improve hydration, making dry or reactive areas feel much softer and smoother over time.
What does Centella Asiatica Extract do for sensitive skin?
Centella asiatica extract helps calm sensitive skin and keeps it comfortable by easing irritation and supporting moisture retention. Using this ingredient helps soothe redness and supports a healthy skin barrier with a very low likelihood of irritation.
Journal of Cosmetic Dermatology, 2025Indian Journal of Pharmaceutical Sciences, 2016
Where does this ampoule go in a skincare routine for sensitive skin?
This ampoule goes in your evening routine after your toner and before your moisturizer. Putting it in the evening keeps things simple and protects your skin around sun exposure.
Can I use this ampoule with retinol, and in what order?
You can use this ampoule with retinol by applying the ampoule after your retinol or soothing toner to help calm and hydrate your skin. Featuring soothing ingredients like panthenol and allantoin with no harsh components, it is safe for sensitive skin and helps keep your skin barrier protected.
Journal of Cosmetic Dermatology, 2024American Journal of Clinical Dermatology, 2002
How often should I use this ampoule?
Apply this treatment in your evening routine, as this timing offers extra safety around sun exposure. Centella Asiatica Extract and Panthenol help calm and hydrate sensitive skin.
Indian Journal of Pharmaceutical Sciences, 2016American Journal of Clinical Dermatology, 2002
Can this ampoule clog pores, cause breakouts or purging for sensitive skin?
This ampoule is unlikely to cause breakouts or clog pores for sensitive skin, as it features soothing ingredients like Panthenol and Allantoin with no harsh components. It is safe for your skin, though some reviewers occasionally mention that it feels a bit heavy.
American Journal of Clinical Dermatology, 2002Journal of Cosmetic Dermatology, 2025
What the research says
Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.
Indian Journal of Pharmaceutical Sciences, 2016Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion.
International Journal of Dermatology, 2008A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin.
Skin Pharmacology and Physiology, 2022Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment.
Journal of Cosmetic Dermatology, 2025Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.
Journal of Alternative and Complementary Medicine, 2020A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.
Aesthetic Plastic Surgery, 2018Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.
Arzneimittel-Forschung, 2000Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.
Auris, Nasus, Larynx, 2020A combination serum containing galactomyces ferment filtrate, dexpanthenol, and Centella asiatica effectively treated post-acne hyperpigmentation in subjects with colored skin by significantly increasing lightness scores in Fitzpatrick skin type V and reducing the melanin index in Fitzpatrick skin type IV compared to placebo.
Skinmed, 2021
Ingredients
Lactobacillus Centella Asiatica Extract Ferment Filtrate, Centella Asiatica Extract, Ceramide Np, Polyhydroxystearic Acid, Betaine, Allantoin, Panthenol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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