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Niacinamide and gluconolactone

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Niacinamide and gluconolactone: depends on the strength

Depends on the strength

Use them together because niacinamide strengthens skin while gluconolactone smooths texture. This pair works well together to improve skin texture without causing irritation. The shopper can use a lower strength if any dryness occurs.

Niacinamide products

Gluconolactone products

Questions and answers

Can you use niacinamide and gluconolactone together?

Yes, you can use niacinamide and gluconolactone together depending on the strength, and products like The INKEY List PHA Toner and BYOMA Clarifying Serum feature both ingredients. Combining them helps improve cell renewal without irritation because niacinamide supports the barrier while mild acids smooth texture.

Which goes first, niacinamide or gluconolactone?

Yes, you can use niacinamide and gluconolactone together depending on the strength, as this combination improves cell renewal without irritation. You can find both ingredients in products like Face Reality sal-C toner, CeraVe Blemish Control Cleanser, SKIN1004 Madagascar Centella Toning Toner, The INKEY List PHA Toner, BYOMA Clarifying Serum, and Biologique Recherche Lotion P50V.

Are niacinamide and gluconolactone good for sensitive skin?

Yes, niacinamide and gluconolactone are good for sensitive skin depending on the strength, as niacinamide supports the skin barrier while mild acids help smooth texture without irritation. You can find this combination in products like The INKEY List PHA Toner, BYOMA Clarifying Serum, and CeraVe Blemish Control Cleanser.

Research on niacinamide and gluconolactone

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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