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Niacinamide and palmitoyl pentapeptide-4

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Niacinamide and palmitoyl pentapeptide-4: depends on the strength

Depends on the strength

Use them together in the same routine, applying niacinamide first and the peptide product second for better skin firmness. Niacinamide helps your skin make more ceramides while peptides signal it to look smoother and younger. You can use them both at once, or use a gentler strength if your skin feels sensitive.

Niacinamide products

Questions and answers

Can you use niacinamide and palmitoyl pentapeptide-4 together?

Yes, you can use niacinamide and palmitoyl pentapeptide-4 together depending on the strength, and they are both found in Olay Eye Lifting Serum. Combining them helps support anti-aging and skin barrier regeneration.

International Journal of Cosmetic Science, 2005Antioxidants, 2021

Which goes first, niacinamide or palmitoyl pentapeptide-4?

Niacinamide and palmitoyl pentapeptide-4 can be used together depending on the strength, and you can find both ingredients in products like Olay Eye Lifting Serum. They complement each other well to support anti-aging and strengthen the skin barrier.

Are niacinamide and palmitoyl pentapeptide-4 good for sensitive skin?

Yes, niacinamide and palmitoyl pentapeptide-4 are beneficial for sensitive skin because they strengthen the skin barrier and reduce irritation. You can find this combination in products like the Olay Eye Lifting Serum.

Research on niacinamide and palmitoyl pentapeptide-4

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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