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Niacinamide and vitamin A

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Niacinamide and vitamin A: depends on the strength

Depends on the strength

Use niacinamide and vitamin A at different times of the day, applying niacinamide in the morning and vitamin A at night, to prevent skin irritation. Vitamin A speeds up cell turnover while niacinamide soothes redness, but combining them too closely can overwhelm the skin. The shopper can switch to a lower strength, or separate the products by using one in the morning and one at night.

Retinoids: a journey from the molecular structures and mechanisms of action to clinical uses in dermatology and adverse effectsWhy Topical Retinoids Are Mainstay of Therapy for Acne

Niacinamide products

Vitamin A products

Questions and answers

Can you use niacinamide and vitamin A together?

Yes, you can use niacinamide and vitamin A together depending on the strength, as lower strengths help reduce irritation while strong retinoids should be separated. Products like Paula's Choice RESIST Triple Active Total Repair Serum, Pond's Age Miracle Night Cream, Vivant DERM-A-GEL, Mesoestetic Cosmelan 2, Osmosis Skincare Renew Level 4 Vitamin A Serum, and Olay Retinol 24 Night Eye Cream combine these ingredients.

Antioxidants, 2021The British Journal of Dermatology, 2010

Which goes first, niacinamide or vitamin A?

Whether niacinamide or vitamin A goes first depends on the strength of the retinoid, and you can use niacinamide in the morning and a low percentage retinoid at night. Strong retinoids should be separated from niacinamide into different routine phases to avoid irritation.

Are niacinamide and vitamin A good for sensitive skin?

Yes, niacinamide and vitamin A can be good for sensitive skin depending on the strength, as low percentage or buffered retinoids paired with niacinamide help reduce irritation and redness. Products like Paula's Choice RESIST Triple Active Total Repair Serum, Pond's Age Miracle Night Cream, Vivant DERM-A-GEL, Mesoestetic Cosmelan 2, Osmosis Skincare Renew Level 4 Vitamin A Serum, and Olay Retinol 24 Night Eye Cream combine these ingredients.

Antioxidants, 2021The British Journal of Dermatology, 2010

Research on niacinamide and vitamin A

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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