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Glycolic acid and gluconolactone

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Glycolic acid and gluconolactone: work well together

Work well together

Use them together in the same routine, applying glycolic acid first and gluconolactone second, because they work nicely as a team. Glycolic acid smooths the skin while gluconolactone adds moisture and keeps the sting away. If it feels too strong, try a lower strength or use them on alternate nights.

The use of polyhydroxy acids (PHAs) in photoaged skinA polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen

Glycolic acid products

Gluconolactone products

Questions and answers

Can you use glycolic acid and gluconolactone together?

Yes, you can use glycolic acid and gluconolactone together because they combine for gentle exfoliation and antioxidant protection. This mix helps provide benefits in reducing complications for acne-prone skin, and products like RNW Der. Clear AHA BHA PHA Peeling Mask, Hero Cosmetics Pore Release Blackhead Clearing Solution, StriVectin Daily Reveal Exfoliating Pads, and BeautyBio Swipe & Glow Peel Pads contain both ingredients.

Clinical, Cosmetic and Investigational Dermatology, 2019

Which goes first, glycolic acid or gluconolactone?

Glycolic acid and gluconolactone work well together to provide gentle exfoliation and antioxidant protection. You can find both ingredients combined in products like RNW Der. Clear AHA BHA PHA Peeling Mask, Hero Cosmetics Pore Release Blackhead Clearing Solution, StriVectin Daily Reveal Exfoliating Pads, and BeautyBio Swipe & Glow Peel Pads.

Research on glycolic acid and gluconolactone

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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