CHANEL Le Lift Crème Fine for combination skin

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Questions and answers

What the research says

• A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.

  Journal of Cosmetic Dermatology, 2015

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.

  International Journal of Cosmetic Science, 2026

• A body cream formulation containing coffee silverskin and Medicago sativa extracts demonstrated stability over 180 days, no in vitro cell toxicity, skin safety without irritant effects, and improved skin hydration after 30 days of use in human subjects.

  Drug Development and Industrial Pharmacy, 2016

• Alfalfa and polycaprolactone composite nanofibers enhanced cellular proliferation of dermal fibroblasts and epidermal keratinocytes in vitro and promoted re-epithelialization and granulation tissue formation in mouse and human skin.

  ACS Applied Materials & Interfaces, 2019

• Medicago sativa methanol extract combined with UVA light enhanced skin and hair pigmentation in a hydroquinone-induced depigmentation mouse model compared to reference, placebo, and control groups.

  Journal of Cosmetic Dermatology, 2022

• Topical sweet potato leaf polyphenols at 100 mg kg-1 and caffeic acid at 30 mg kg-1 protected BALB/c hairless mice from UV-induced skin damage by improving moisture and antioxidant enzyme activities while reducing inflammation and oxidative stress markers.

  Food & Function, 2022

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

  International Journal of Cosmetic Science, 2025

• Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.

  Journal of Cosmetic Dermatology, 2025

• Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.

  Contemporary Clinical Trials Communications, 2021

• Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.

  Journal of Cosmetic Dermatology, 2024

Ingredients

Water, Glycerin, Alcohol, Propanediol, Dimethicone, Lauroyl Lysine, Camellia Oleifera Seed Oil, Coco-Caprylate Caprate, Cetearyl Alcohol, Ammonium Acryloyldimethyltaurate Vp Copolymer, Ipomoea Batatas Root Extract, Yeast Extract, Medicago Sativa Extract, Butyrospermum Parkii Butter Shea Butter, Dipropylene Glycol, Phenoxyethanol, Glyceryl Stearate, Peg-100 Stearate, Tocopheryl Acetate, Cetearyl Glucoside, Dimethicone Crosspolymer, Parfum, Caprylyl Glycol, Xanthan Gum, Propylene Glycol, Sodium Hyaluronate, Adenosine, Arginine, Lactic Acid, Phytic Acid, Ethylhexylglycerin, Sodium Hydroxide, Tocopherol, Hydrochloric Acid, Sodium Citrate, Palmitoyl Tetrapeptide-7, Sodium Benzoate, Citric Acid, Ci 14700 Red 4, Ci 19140 Yellow 5

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.