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Biossance Squalane + Omega Repair Cream for oily acne-prone skin

Biossance Squalane + Omega Repair Cream

High

  • AverageOily Skin Fit
  • AverageEffectiveness
  • ExcellentSafety

A great choice for oily acne-prone skin; a few moisturizers fit it even better.

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers excellent moisturizing for your oily skin, as squalane and glycerin hydrate and enhance barrier resilience without causing irritation. While beneficial for overall skin health, these ingredients do not specifically target your concerns of acne, blemishes, and breakouts.
  • The formula provides general skincare benefits, supporting hydration and barrier function for oily skin.
  • The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components like squalane and hyaluronic acid.

How to apply

  • Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
  • Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
  • Gently press a small amount into your skin and avoid rubbing to keep pores clear.
  • Apply on clean, slightly damp skin to help the product absorb better and control oil.
  • Avoid the sensitive eye area and do a simple patch test before your first use.

People Say

★4.3Overall rating based on 3.0k+ reviews

Many users love its luxurious, non-greasy texture and find it soothing for sensitive skin, also noting it works well as a makeup base. A significant portion of reviews consistently cite a distinct, unpleasant natural scent as a major drawback, despite the product's effective performance in plumping and smoothing skin texture. Some users also find the price point high and a minority with extremely dry skin felt it wasn't rich enough.

Highlights

  • Deep hydration Mostly Mentioned
    • “melts into my skin like butter”
    • “leaves skin feeling instantly hydrated and plump”
    • “my dry patches? gone.”
  • Unpleasant scent Mostly Mentioned
    • “smells like dirty feet”
    • “smells straight up fishy”
    • “weird fermented smell”
  • Non-greasy texture Often Mentioned
    • “rich but lightweight”
    • “absorbs fast, no residue”
    • “decadent whipped texture”
  • Excellent makeup base Sometimes Noted
    • “makeup sits better”
    • “great primer for dry skins”
    • “leaves a lit-from-within glow”
  • Soothing for sensitive Sometimes Noted
    • “only one that doesn't make my skin flare up”
    • “calm and clear”
  • High price point Sometimes Noted
    • “expensive for what it is”
    • “wish it were more concentrated for the cost”
    • “splurge product”
  • Not rich enough Rarely Noted
    • “have to use more product than expected”
    • “felt too lightweight”
    • “skin felt parched hours later”
  • Packaging issues Rarely Noted
    • “lid was busted”
    • “jar arrived open”
    • “broken glass”

Sources: lovi.care, sephora.com.au, biossance.com, reddit.com, womenshealthmag.com, organicbeautylover.com, and more

Questions and answers

What makes Biossance Squalane + Omega Repair Cream a great fit for oily acne-prone skin?

Biossance Squalane + Omega Repair Cream is a great fit because squalane and glycerin hydrate and strengthen the skin barrier without causing irritation. The formula has an excellent safety profile with no harsh ingredients, making it very gentle for your skin.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this cream a good fit for oily acne-prone skin?

Squalane, glycerin, and Ceramide NP make this cream a good fit because they hydrate and strengthen your skin barrier without causing irritation. While they support overall skin health, these ingredients do not specifically target blemishes and breakouts.

Clinical, Cosmetic and Investigational Dermatology, 2017

What does Squalane do for oily acne-prone skin?

Squalane may help keep oily skin soft and smooth, but oxidized squalene can trigger inflammation in acne-prone skin. Because of this, oily acne-prone skin needs lightweight, non-greasy ingredients that balance moisture without clogging pores.

The Journal of Investigative Dermatology, 2006

What do Ceramides do for oily acne-prone skin?

Ceramides help keep oily acne-prone skin calm and smooth by strengthening the skin barrier and locking in moisture. Since acne-prone skin often has lower levels of these natural lipids, adding ceramides helps reduce irritation, redness, and moisture loss. A product for this skin type needs barrier-supporting ingredients like ceramides and gentle hydrators to prevent dryness and balance oil.

Journal of Cosmetic Dermatology, 2026Journal of Cosmetic Dermatology, 2023

Where does this cream go in a skincare routine for oily acne-prone skin?

This cream goes in your morning and evening routine as your moisturizer step, right after your hydrating toner or treatment. It helps keep oily skin hydrated and supports your skin barrier without causing irritation, though it does not actively treat breakouts.

The Journal of Dermatological Treatment, 2022Clinical, Cosmetic and Investigational Dermatology, 2017

Can I use this cream with retinol, and in what order?

You can use this moisturizing treatment with retinol by applying it either before or after your retinol to help soothe your skin and keep it comfortable. Using a barrier-supporting moisturizer alongside active treatments is unlikely to cause irritation and may make your routine easier to stick with.

Cutis, 2006The Journal of Dermatology, 2014

How often should I use this cream?

This cream is a great fit for your oily skin and can be used daily as part of your morning and evening routine. Ingredients like squalane and glycerin hydrate your skin and help strengthen its barrier without causing irritation or clogging pores.

Health Science Reports, 2021Clinical, Cosmetic and Investigational Dermatology, 2017

Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream is unlikely to clog pores or cause purging on oily skin, as it relies on lightweight hydrating ingredients like squalane and glycerin that hydrate without harshness or irritation. However, because it does not target blemishes or breakouts directly, it may not help improve acne concerns.

Clinical, Cosmetic and Investigational Dermatology, 2017

Can I use this cream around the eyes or on my body?

This cream is suitable for use around the eyes and on the body because its gentle formula provides safe hydration and barrier support without harsh ingredients. It has an excellent safety profile, making it very well tolerated by delicate or sensitive areas.

Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017
  • Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion.

    International Journal of Dermatology, 2008
  • A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin.

    Skin Pharmacology and Physiology, 2022
  • Topical application of a vitamin C-squalene bioconjugate significantly increased epidermal thickness, type III collagen production, and glycosaminoglycans production in human skin explants compared to free vitamin C and vitamin C-palmitate.

    Scientific Reports, 2020
  • Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

    Molecules, 2025
  • Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

    Antioxidants, 2025
  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011
  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022
  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019
  • A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

    Lasers in Medical Science, 2025
  • A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

    International Journal of Cosmetic Science, 2025

Ingredients

Water, Squalane, Glycerin, Caprylic Capric Triglyceride, Isoamyl Laurate, Butyrospermum Parkii Butter Shea Butter, Sorbitan Olivate, Cetearyl Olivate, Ceramide Np, Jojoba Esters, Sodium Hyaluronate, Euterpe Oleracea Sterols, Linoleic Acid, Oleic Acid, Linolenic Acid, Ethyl Linoleate, Tocopherol, Isoamyl Cocoate, Cetyl Palmitate, Sorbitan Palmitate, Cetearyl Alcohol, Ethylhexylglycerin, Carbomer, Sodium Hydroxide, Phenoxyethanol, Sodium Gluconate

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

How does it fit your skin?

Scan your face, then any product: Lovi shows how well it fits you and what fits even better.