Cetaphil vs Clinique
Cetaphil and Clinique are two American skincare brands offering distinct approaches to daily regimens. The former is loved for its gentle cleansers, moisturizers, serums, and sunscreens formulated with glycerin, niacinamide, and panthenol to suit oily skin and combination skin best. Conversely, the latter is widely loved for its thoughtful range of moisturizers, serums, makeup removers, and eye products incorporating hyaluronic acid, glycerin, and caffeine to suit dry sensitive skin and oily skin best. While both brands address similar skin concerns through targeted formulations, they differ primarily in their founding heritage and proprietary blend of active ingredients.
Cetaphil is an American skincare brand founded in 1947 and owned by Galderma Group AG.
en.wikipedia.orgcetaphil.co.uk
Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..
en.wikipedia.orgelcompanies.combusinesswire.comglossy.co
This page compares some of the most popular Cetaphil and Clinique products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Cetaphil vs Clinique products
People Say
Gentle on sensitive skin Mostly MentionedMostly Mentioned
- “The only thing my reactive skin tolerates. — Cetaphil Gentle Skin Cleanser”
- “No breakouts since switching to this. — Cetaphil Gentle Skin Cleanser”
- “cleans without stripping — Cetaphil Daily Facial Cleanser”
- “never irritated my eyes — Clinique All About Eyes”
Hydration and moisture Mostly MentionedOften Mentioned
- “cleared up flaky skin — Cetaphil Moisturizing Cream”
- “healed my dry patches — Cetaphil Moisturising Cream”
- “Leaves my face feeling soft, not tight. — Cetaphil Gentle Skin Cleanser”
- “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+”
Lightweight and non-greasy absorption Often MentionedMostly Mentioned
- “absorbs instantly — Cetaphil Moisturizing Lotion”
- “Absorbs quickly into skin without residue — Cetaphil Daily Hydrating Lotion”
- “sinks in immediately — Clinique moisture surge”
- “sinks in instantly — Clinique Dramatically Different Moisturizing Gel”
Works well under makeup Rarely NotedOften Mentioned
- “foundation glides on — Clinique moisture surge”
- “holds concealer in place — Clinique All About Eyes”
- “perfect primer base — Clinique Dramatically Different Moisturizing Gel”
- “Layers really well under makeup — Cetaphil Daily Hydrating Lotion”
Smoother skin and texture improvement Rarely NotedSometimes Noted
- “skin feels silky smooth — Clinique Smart Clinical Repair Wrinkle Correcting Serum”
- “leaves face porcelain smooth — Clinique 7 Day Scrub Cream Rinse-Off Formula”
- “Skin looks smoother and even-toned — Clinique Clarifying Lotion 2”
- “Skin felt softer after one use — Cetaphil Gentle Exfoliating SA Cleanser”
Gentle exfoliation Rarely NotedSometimes Noted
- “gentle enough for everyday — Clinique 7 Day Scrub Cream Rinse-Off Formula”
- “You will see the dirt with one wipe — Clinique Clarifying Lotion 2”
- “Micro-fine granules don't irritate — Cetaphil Extra Gentle Daily Scrub”
Lack of lather or unusual texture Often MentionedSometimes Noted
- “hard to rinse off — Clinique 7 Day Scrub Cream Rinse-Off Formula”
- “Left an oily film on my T-zone — Clinique Dramatically Different Moisturizing Lotion+”
- “feels a bit sticky — Clinique Moisture Surge Overnight Mask”
- “Miss the bubbles, feels like washing with lotion. — Cetaphil Gentle Skin Cleanser”
Unpleasant scent or chemical smell Sometimes NotedSometimes Noted
- “Smells like nail polish remover — Clinique Clarifying Lotion 2”
- “Smells like old oil — Clinique Take The Day Off Cleansing Balm”
- “Has a weird plastic-like smell — Clinique Dramatically Different Moisturizing Lotion+”
- “Overpowering masking fragrance — Cetaphil Gentle Cleansing Bar”
High price point Rarely NotedOften Mentioned
- “expensive for drugstore — Cetaphil Moisturizing Cream”
- “jar is too small for the cost — Clinique moisture surge”
Cetaphil vs Clinique routines for dry skin
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Cleanser
Gentle Skin Cleanser
Morning · Evening · Once a week
€14.99
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Hydrating Toner
COSRX Propolis Synergy Toner
Morning
€18.55
-
Moisturizer
Rich Hydrating Night Cream
Morning · Evening · Once a week
€12.86
-
SPF
Redness Relieving Daily Facial Moisturizer SPF 40
Morning
€31.99
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€16.10
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
€18.52
-
Nourishing Mask
Anua Heartleaf 77% Soothing Sheet Mask
Once a week
€19.90
-
Cleanser
all about clean
Morning · Evening · Once a week
€28.05
-
Hydrating Toner
COSRX Propolis Synergy Toner
Morning
€18.55
-
Moisturizer
Smart Clinical Repair Lifting Face + Neck Cream
Morning · Evening · Once a week
€94.95
-
SPF
Purito Daily Soft Touch Sunscreen
Morning
€12.98
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
€25.90
-
Serum or Treatment
Smart Clinical Repair Wrinkle Correcting Serum
Evening · Once a week
€87.95
-
Nourishing Mask
Moisture Surge Overnight Mask
Once a week
€26.95
Cetaphil vs Clinique routines for oily skin
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Cleanser
Daily Facial Cleanser
Morning · Evening · Once a week
€21.95
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€19.99
-
Moisturizer
Ceramide Serum
Morning · Evening · Once a week
€35.60
-
SPF
Oil Control
Morning
€23.45
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€40.00
-
Cleansing Toner
Pixi Glow Tonic
Evening
€29.29
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
€18.52
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€49.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
€79.97
-
Cleanser
Redness Solutions Soothing Cleanser
Morning · Evening · Once a week
€31.05
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
€19.99
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
€30.25
-
SPF
make p:rem UV Defense Me Blue Ray Sun Cream
Morning
€34.30
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
€25.90
-
Cleansing Toner
Clarifying Lotion 2
Evening
€47.15
- Serum or Treatment Even Better Clinical Dark Spot Corrector Evening · Once a week
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€49.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
€79.97
Cetaphil vs Clinique routines for combination skin
-
Cleanser
Daily Facial Cleanser
Morning · Evening · Once a week
€21.95
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Ceramide Serum
Morning · Evening · Once a week
€35.60
-
SPF
Oil Control
Morning
€23.45
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€40.00
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€17.15
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
€18.52
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€49.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
€79.97
-
Cleanser
all about clean
Morning · Evening · Once a week
€28.05
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
€30.25
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
€25.90
-
Cleansing Toner
Clarifying Lotion 2
Evening
€47.15
- Serum or Treatment Even Better Clinical Dark Spot Corrector Evening · Once a week
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€49.00
-
Cleansing Mask
HERBIVORE Botanicals Blue Tansy BHA and Enzyme Pore Refining Mask
Once a week
€79.97
Questions and answers
Cetaphil or Clinique: which is better?
Cetaphil is better for dry skin, where it achieves a High routine fit compared to an Average fit for Clinique. Reviewers also note that Cetaphil is more gentle on sensitive skin and offers better hydration and moisture at a lower price point.
What is the difference between Cetaphil and Clinique?
Cetaphil is generally better for hydration and sensitive skin, offering a High routine fit for dry skin while Clinique provides an Average fit. Both brands share a High fit level for oily and sensitive skin. Additionally, the products on this page for Cetaphil feature key ingredients like niacinamide and glycerin to support the skin barrier.
The British Journal of Dermatology, 2002American Journal of Clinical Dermatology, 2002
Cetaphil or Clinique for dry skin?
Cetaphil is the better choice for dry skin because Lovi rates its routine fit as High compared to Clinique's Average fit. Reviewers also report that Cetaphil provides better overall hydration and moisture.
Cetaphil or Clinique: which cleanser is better?
Cetaphil is generally better for gentle cleansing, as its products on this page achieve a high or superior Lovi fit level for sensitive and dry skin compared to lower ratings for cleansers like all about clean from Clinique. Reviewers also note that Cetaphil offers gentle, non-stripping cleansers that help maintain skin comfort.
Which is more affordable, Cetaphil or Clinique?
Cetaphil is more affordable, as Clinique reviewers often mention a high price point while Cetaphil is noted for having a lower price.
Cetaphil or Clinique: which is better for mature skin?
Cetaphil has a High routine fit for mature skin, making it a better option than Clinique, which has an Average routine fit. Reviewers note that Cetaphil provides gentle, non-stripping cleansers and hydrating, non-greasy moisturizers.
Cetaphil or Clinique: which offers better hydration and moisture?
Cetaphil is better for hydration and moisture, as review themes show it outperforms Clinique in this category. The products on this page feature hydrating ingredients like hyaluronic acid and glycerin.
Cetaphil or Clinique: which works better under makeup?
Clinique works better under makeup compared to Cetaphil, as its products on this page are noted by reviewers for functioning well as effective makeup bases.
Cetaphil or Clinique for oily skin?
Both brands are a High fit for oily skin. Reviewers note that Cetaphil provides gentle, non-stripping cleansers while Clinique offers oil-controlling and smoothing moisturizers.
Cetaphil or Clinique: which moisturizer is better?
Cetaphil is better for dry skin and general hydration among the products on this page, achieving a high routine fit compared to Clinique's average fit. Reviewers note that Cetaphil offers hydrating, non-greasy moisturizers that are gentle on sensitive skin.
Cetaphil or Clinique for sensitive skin?
Both Cetaphil and Clinique achieve a High fit level for sensitive skin on this page. Reviewers note that Cetaphil performs better for being gentle on sensitive skin.
Cetaphil or Clinique for acne-prone skin?
Cetaphil is a better fit for acne-prone skin, achieving a High routine fit compared to Clinique's Average level. Reviewers report that Cetaphil provides gentle, non-stripping cleansers and hydrating, non-greasy moisturizers that are well suited for blemish-prone complexions.
Research behind their key ingredients
Effects of menthol and cold on histamine-induced itch and skin reactions in man
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin
Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Colloidal Oatmeal <em>(Avena Sativa)</em> Improves Skin Barrier Through Multi-Therapy Activity
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome
Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Algae extract protection effect on oxidized protein level in human stratum corneum
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Modulating effects of oatmeal extracts in the sodium lauryl sulfate skin irritancy model
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Functional properties and skin care effects of sodium trehalose sulfate
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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