Cetaphil vs Clinique
Cetaphil and Clinique are both American skincare brands known for nurturing diverse skin types through distinct formulations. The former is loved for its gentle cleansers, soothing moisturizers, targeted serums, and protective sunscreens formulated with glycerin, niacinamide, and panthenol to suit acne-prone and dry sensitive skin best. The latter is widely loved for its thoughtful range of moisturizers, serums, makeup removers, and eye products incorporating hydrating hyaluronic acid, nourishing glycerin, and invigorating caffeine to comfortably suit dry sensitive and oily skin. While both share a dedication to skin health, they differ in their foundational ingredients, with the first brand relying on niacinamide and panthenol for barrier restoration and the second employing hyaluronic acid and caffeine for moisture retention and protection.
Cetaphil is an American skincare brand founded in 1947 and owned by Galderma Group AG.
en.wikipedia.orgcetaphil.co.uk
Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..
en.wikipedia.orgelcompanies.combusinesswire.comglossy.co
This page compares some of the most popular Cetaphil and Clinique products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Cetaphil vs Clinique products
- moisture surge
-
Take The Day Off Cleansing Balm
AED 123.26
-
Dramatically Different Moisturizing Lotion+
AED 123.95
-
All About Eyes
AED 164.29
-
Dramatically Different Moisturizing Gel
AED 89.47
-
Smart Clinical Repair Wrinkle Correcting Serum
AED 297.75
-
Moisture Surge Overnight Mask
AED 292.69
- Clarifying Lotion 2
People Say
Gentle on sensitive skin Mostly MentionedMostly Mentioned
- “The only thing my reactive skin tolerates. — Cetaphil Gentle Skin Cleanser”
- “No breakouts since switching to this. — Cetaphil Gentle Skin Cleanser”
- “cleans without stripping — Cetaphil Daily Facial Cleanser”
- “never irritated my eyes — Clinique All About Eyes”
Hydration and moisture Mostly MentionedOften Mentioned
- “cleared up flaky skin — Cetaphil Moisturizing Cream”
- “healed my dry patches — Cetaphil Moisturising Cream”
- “Leaves my face feeling soft, not tight. — Cetaphil Gentle Skin Cleanser”
- “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+”
Lightweight and non-greasy absorption Often MentionedMostly Mentioned
- “absorbs instantly — Cetaphil Moisturizing Lotion”
- “Absorbs quickly into skin without residue — Cetaphil Daily Hydrating Lotion”
- “sinks in immediately — Clinique moisture surge”
- “sinks in instantly — Clinique Dramatically Different Moisturizing Gel”
Works well under makeup Rarely NotedOften Mentioned
- “foundation glides on — Clinique moisture surge”
- “holds concealer in place — Clinique All About Eyes”
- “perfect primer base — Clinique Dramatically Different Moisturizing Gel”
- “Layers really well under makeup — Cetaphil Daily Hydrating Lotion”
Smoother skin and texture improvement Rarely NotedSometimes Noted
- “skin feels silky smooth — Clinique Smart Clinical Repair Wrinkle Correcting Serum”
- “leaves face porcelain smooth — Clinique 7 Day Scrub Cream Rinse-Off Formula”
- “Skin looks smoother and even-toned — Clinique Clarifying Lotion 2”
- “Skin felt softer after one use — Cetaphil Gentle Exfoliating SA Cleanser”
Gentle exfoliation Rarely NotedSometimes Noted
- “gentle enough for everyday — Clinique 7 Day Scrub Cream Rinse-Off Formula”
- “You will see the dirt with one wipe — Clinique Clarifying Lotion 2”
- “Micro-fine granules don't irritate — Cetaphil Extra Gentle Daily Scrub”
Lack of lather or unusual texture Often MentionedSometimes Noted
- “hard to rinse off — Clinique 7 Day Scrub Cream Rinse-Off Formula”
- “Left an oily film on my T-zone — Clinique Dramatically Different Moisturizing Lotion+”
- “feels a bit sticky — Clinique Moisture Surge Overnight Mask”
- “Miss the bubbles, feels like washing with lotion. — Cetaphil Gentle Skin Cleanser”
Unpleasant scent or chemical smell Sometimes NotedSometimes Noted
- “Smells like nail polish remover — Clinique Clarifying Lotion 2”
- “Smells like old oil — Clinique Take The Day Off Cleansing Balm”
- “Has a weird plastic-like smell — Clinique Dramatically Different Moisturizing Lotion+”
- “Overpowering masking fragrance — Cetaphil Gentle Cleansing Bar”
High price point Rarely NotedOften Mentioned
- “expensive for drugstore — Cetaphil Moisturizing Cream”
- “jar is too small for the cost — Clinique moisture surge”
Cetaphil vs Clinique routines for dry skin
-
Cleanser
Gentle Skin Cleanser
Morning · Evening · Once a week
AED 44.60
-
Hydrating Toner
Healthy Radiance Brightness Refresh Toner
Morning
AED 79.00
-
Moisturizer
Rich Hydrating Night Cream
Morning · Evening · Once a week
AED 50.00
-
SPF
Daily Facial Moisturizer
Morning
AED 84.00
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
AED 35.29
-
Cleansing Toner
ROUND LAB 1025 Dokdo Cleansing Water
Evening
AED 38.99
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
AED 88.43
-
Enzyme Powder
VT Cica Mild Powder Wash
Once a week
AED 47.62
-
Nourishing Mask
Mediheal Watermide Essential Mask
Once a week
AED 65.00
-
Cleanser
all about clean
Morning · Evening · Once a week
AED 209.14
-
Moisturizer
Smart Clinical Repair Lifting Face + Neck Cream
Morning · Evening · Once a week
AED 553.77
-
SPF
Dr.G Green Mild Up Sun+
Morning
AED 81.00
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
AED 123.26
- Cleansing Toner Clarifying Lotion 2 Evening
-
Serum or Treatment
Smart Clinical Repair Wrinkle Correcting Serum
Evening · Once a week
AED 297.75
-
Enzyme Powder
VT Cica Mild Powder Wash
Once a week
AED 47.62
-
Nourishing Mask
Moisture Surge Overnight Mask
Once a week
AED 292.69
Buy Cetaphil routine · AED 319.93 · 82% fit
Buy Clinique routine · AED 1,605.23 · 66% fitSee multi-brand routine · 96% fit
Cetaphil vs Clinique routines for oily skin
-
Cleanser
Oily Skin Cleanser
Morning · Evening · Once a week
AED 54.95
-
Hydrating Toner
Healthy Radiance Brightness Refresh Toner
Morning · Once a week
AED 79.00
-
Moisturizer
Daily Hydrating Lotion
Morning · Evening · Once a week
AED 81.00
-
SPF
Oil Control
Morning
AED 25.69
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
AED 179.45
-
Cleansing Toner
Pixi Glow Tonic
Evening
AED 120.00
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
AED 88.43
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
AED 101.09
-
Cleansing Mask
Revision Skincare Black Mask
Once a week
AED 204.00
-
Cleanser
Redness Solutions Soothing Cleanser
Morning · Evening · Once a week
AED 342.00
-
Hydrating Toner
Some By Mi Snail Truecica Miracle Repair Toner
Morning · Once a week
AED 49.99
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
AED 89.47
-
SPF
d'Alba UVessence Mild Waterfull Sun Cream SPF 50
Morning
AED 92.70
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
AED 123.26
- Cleansing Toner Clarifying Lotion 2 Evening
- Serum or Treatment Even Better Clinical Dark Spot Corrector Evening · Once a week
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
AED 101.09
-
Cleansing Mask
Revision Skincare Black Mask
Once a week
AED 204.00
Buy Cetaphil routine · AED 854.61 · 81% fit
Buy Clinique routine · AED 1,002.51 · 79% fitSee multi-brand routine · 97% fit
Cetaphil vs Clinique routines for combination skin
-
Cleanser
Oily Skin Cleanser
Morning · Evening · Once a week
AED 54.95
-
Hydrating Toner
Healthy Radiance Brightness Refresh Toner
Morning · Once a week
AED 79.00
-
Moisturizer
Daily Hydrating Lotion
Morning · Evening · Once a week
AED 81.00
-
SPF
Oil Control
Morning
AED 25.69
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
AED 179.45
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
AED 53.12
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
AED 88.43
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
AED 101.09
-
Cleansing Mask
KORA Organics Turmeric Brightening & Exfoliating Mask
Once a week
AED 122.93
-
Cleanser
all about clean
Morning · Evening · Once a week
AED 209.14
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
AED 145.00
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
AED 89.47
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
AED 123.26
- Cleansing Toner Clarifying Lotion 2 Evening
- Serum or Treatment Even Better Clinical Dark Spot Corrector Evening · Once a week
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
AED 101.09
-
Cleansing Mask
KORA Organics Turmeric Brightening & Exfoliating Mask
Once a week
AED 122.93
Buy Cetaphil routine · AED 706.66 · 82% fit
Buy Clinique routine · AED 790.89 · 72% fitSee multi-brand routine · 96% fit
Questions and answers
Cetaphil or Clinique: which is better?
Cetaphil is generally better for overall hydration and gentleness on sensitive skin, offering a High routine fit across almost all skin types. Clinique is often preferred for specialized texture improvement and makeup performance, though it carries a higher price point.
What is the difference between Cetaphil and Clinique?
Cetaphil is generally gentler on sensitive skin and provides superior hydration, whereas Clinique is often preferred for smoothing texture and working well under makeup. For the products on this page, Cetaphil is more affordable, while Clinique has a higher price point.
Cetaphil or Clinique for dry skin?
Cetaphil is a better fit for dry skin, offering a High routine fit compared to Clinique's Average level. The products on this page for Cetaphil include ingredients like glycerin and hyaluronic acid, which help deliver hydration.
Cetaphil or Clinique: which cleanser is better?
Cetaphil is better for cleansers on this page, as its products on this page achieve superior and high fit levels across a wide range of skin types, whereas Clinique's cleansers often receive low or warning ratings. Reviewers also mention that Cetaphil provides gentle, non-stripping cleansers.
Which is more affordable, Cetaphil or Clinique?
Cetaphil is more affordable than Clinique, as high price points are noted as a drawback for Clinique products while Cetaphil is recognized for its lower price point.
Cetaphil or Clinique: which is better for anti-aging and mature skin?
Cetaphil has a High routine fit for mature skin among the products on this page, whereas Clinique has an Average routine fit. Reviewers note that Cetaphil excels in hydration and moisture, which helps support mature skin.
Cetaphil or Clinique: which brand performs better for fading dark spots?
Cetaphil is a better fit for skin with dark spots, as the products on this page achieve a High Lovi fit level for this concern. Niacinamide, a key ingredient found across Cetaphil products, helps suppress cutaneous pigmentation.
Cetaphil or Clinique: which is better for makeup removal and performance under makeup?
Clinique is better for makeup removal and performance under makeup because the products on this page help dissolve makeup deeply and work well as makeup bases.
Cetaphil or Clinique for oily skin?
Both brands offer a High routine fit for oily skin on the products on this page. Reviewers note that Cetaphil provides gentle, non-stripping cleansers, while Clinique features oil-controlling and smoothing moisturizers.
Cetaphil or Clinique: which moisturizer is better?
Cetaphil is better for moisture and hydration among the products on this page, as it is rated High for routine fit in dry skin compared to Clinique's Average fit. The products on this page help deliver key moisturizing ingredients like glycerin and hyaluronic acid to the skin.
Cetaphil or Clinique for sensitive skin?
Both Cetaphil and Clinique achieve a High routine fit for sensitive skin, but the products on this page show Cetaphil outperforming Clinique specifically for gentleness on sensitive skin. Cetaphil features key ingredients like niacinamide and panthenol, which may help soothe irritation and support the skin barrier.
The British Journal of Dermatology, 2002American Journal of Clinical Dermatology, 2002
Cetaphil or Clinique for acne-prone skin?
Cetaphil is a better fit for acne-prone skin, achieving a High routine fit compared to Clinique's Average fit on the products on this page. Reviewers frequently note that Cetaphil offers gentle, non-stripping cleansers and hydrating, non-greasy moisturizers that help manage acne-prone skin effectively.
Research behind their key ingredients
Effects of menthol and cold on histamine-induced itch and skin reactions in man
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin
Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Colloidal Oatmeal <em>(Avena Sativa)</em> Improves Skin Barrier Through Multi-Therapy Activity
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome
Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Algae extract protection effect on oxidized protein level in human stratum corneum
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Modulating effects of oatmeal extracts in the sodium lauryl sulfate skin irritancy model
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Functional properties and skin care effects of sodium trehalose sulfate
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-

Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.


























































