Cetaphil vs Clinique
Cetaphil and Clinique are American skincare brands known for their thoughtful lineups of cleansers, moisturizers, serums, sunscreens, makeup removers, and eye products. The first brand features nourishing glycerin, niacinamide, and panthenol to suit combination skin and oily acne-prone skin best, while the second incorporates hydrating hyaluronic acid, nourishing glycerin, and invigorating caffeine to suit dry sensitive skin and oily skin best. They differ primarily in their ingredient profiles and targeted solutions, such as the former offering standout options like the Healthy Radiance Antioxidant-C Serum and the latter providing alternatives like the Clarifying Do-Over Peel.
Cetaphil is an American skincare brand founded in 1947 and owned by Galderma Group AG.
en.wikipedia.orgcetaphil.co.uk
Clinique is an American skincare brand founded in 1968 and owned by The Estée Lauder Companies Inc..
en.wikipedia.orgelcompanies.combusinesswire.comglossy.co
This page compares some of the most popular Cetaphil and Clinique products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Popular Cetaphil vs Clinique products
People Say
Gentle on sensitive skin Mostly MentionedMostly Mentioned
- “The only thing my reactive skin tolerates. — Cetaphil Gentle Skin Cleanser”
- “No breakouts since switching to this. — Cetaphil Gentle Skin Cleanser”
- “cleans without stripping — Cetaphil Daily Facial Cleanser”
- “never irritated my eyes — Clinique All About Eyes”
Hydration and moisture Mostly MentionedOften Mentioned
- “cleared up flaky skin — Cetaphil Moisturizing Cream”
- “healed my dry patches — Cetaphil Moisturising Cream”
- “Leaves my face feeling soft, not tight. — Cetaphil Gentle Skin Cleanser”
- “Keeps my dry patches at bay all day — Clinique Dramatically Different Moisturizing Lotion+”
Lightweight and non-greasy absorption Often MentionedMostly Mentioned
- “absorbs instantly — Cetaphil Moisturizing Lotion”
- “Absorbs quickly into skin without residue — Cetaphil Daily Hydrating Lotion”
- “sinks in immediately — Clinique moisture surge”
- “sinks in instantly — Clinique Dramatically Different Moisturizing Gel”
Works well under makeup Rarely NotedOften Mentioned
- “foundation glides on — Clinique moisture surge”
- “holds concealer in place — Clinique All About Eyes”
- “perfect primer base — Clinique Dramatically Different Moisturizing Gel”
- “Layers really well under makeup — Cetaphil Daily Hydrating Lotion”
Smoother skin and texture improvement Rarely NotedSometimes Noted
- “skin feels silky smooth — Clinique Smart Clinical Repair Wrinkle Correcting Serum”
- “leaves face porcelain smooth — Clinique 7 Day Scrub Cream Rinse-Off Formula”
- “Skin looks smoother and even-toned — Clinique Clarifying Lotion 2”
- “Skin felt softer after one use — Cetaphil Gentle Exfoliating SA Cleanser”
Gentle exfoliation Rarely NotedSometimes Noted
- “gentle enough for everyday — Clinique 7 Day Scrub Cream Rinse-Off Formula”
- “You will see the dirt with one wipe — Clinique Clarifying Lotion 2”
- “Micro-fine granules don't irritate — Cetaphil Extra Gentle Daily Scrub”
Lack of lather or unusual texture Often MentionedSometimes Noted
- “hard to rinse off — Clinique 7 Day Scrub Cream Rinse-Off Formula”
- “Left an oily film on my T-zone — Clinique Dramatically Different Moisturizing Lotion+”
- “feels a bit sticky — Clinique Moisture Surge Overnight Mask”
- “Miss the bubbles, feels like washing with lotion. — Cetaphil Gentle Skin Cleanser”
Unpleasant scent or chemical smell Sometimes NotedSometimes Noted
- “Smells like nail polish remover — Clinique Clarifying Lotion 2”
- “Smells like old oil — Clinique Take The Day Off Cleansing Balm”
- “Has a weird plastic-like smell — Clinique Dramatically Different Moisturizing Lotion+”
- “Overpowering masking fragrance — Cetaphil Gentle Cleansing Bar”
High price point Rarely NotedOften Mentioned
- “expensive for drugstore — Cetaphil Moisturizing Cream”
- “jar is too small for the cost — Clinique moisture surge”
Cetaphil vs Clinique routines for dry skin
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Cleanser
Gentle Skin Cleanser
Morning · Evening · Once a week
€15.19
-
Hydrating Toner
Paula's Choice Advanced Replenishing Toner
Morning
€34.00
-
Moisturizer
Rich Hydrating Night Cream
Morning · Evening · Once a week
€19.99
-
SPF
Daily Facial Moisturizer
Morning
€19.51
-
Pre-Cleanser
MISSHA Ultra Hyalon Cleansing Cream
Evening · Once a week
€10.97
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
€15.59
-
Nourishing Mask
Abib Rice Probiotics Overnight Mask
Once a week
€15.30
-
Cleanser
all about clean
Morning · Evening · Once a week
€34.50
-
Hydrating Toner
Paula's Choice Advanced Replenishing Toner
Morning
€34.00
-
Moisturizer
Smart Clinical Repair Lifting Face + Neck Cream
Morning · Evening · Once a week
€48.89
-
SPF
Purito Daily Soft Touch Sunscreen
Morning
€12.98
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
€22.53
-
Serum or Treatment
Smart Clinical Repair Wrinkle Correcting Serum
Evening · Once a week
€71.30
-
Nourishing Mask
Moisture Surge Overnight Mask
Once a week
€24.50
Cetaphil vs Clinique routines for oily skin
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Cleanser
Daily Facial Cleanser
Morning · Evening · Once a week
€24.59
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Daily Hydrating Lotion
Morning · Evening · Once a week
€17.79
-
SPF
Oil Control
Morning
€23.48
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€97.52
-
Cleansing Toner
Caudalie Vinopure Purifying Toner
Evening
€16.90
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
€15.59
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€16.79
-
Cleanser
Redness Solutions Soothing Cleanser
Morning · Evening · Once a week
€25.50
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
€24.46
-
SPF
d'Alba UVessence Mild Waterfull Sun Cream SPF 50
Morning
€16.99
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
€22.53
-
Cleansing Toner
Clarifying Lotion 2
Evening
€34.39
-
Serum or Treatment
Smart Clinical Repair Wrinkle Correcting Serum
Evening · Once a week
€71.30
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
VT Cosmetics Cica Purifying Mask
Once a week
€16.79
Cetaphil vs Clinique routines for combination skin
-
Cleanser
Daily Facial Cleanser
Morning · Evening · Once a week
€24.59
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Daily Hydrating Lotion
Morning · Evening · Once a week
€17.79
-
SPF
Oil Control
Morning
€23.48
-
Pre-Cleanser
Shu Uemura Ultime8 Sublime Beauty Cleansing Oil
Evening · Once a week
€97.52
-
Cleansing Toner
Medicube Zero Pore Pad 2.0
Evening
€16.98
-
Serum or Treatment
Gentle Exfoliating SA Lotion
Evening · Once a week
€15.59
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Origins Original Skin Retexturizing Mask with Rose Clay
Once a week
€28.50
-
Cleanser
all about clean
Morning · Evening · Once a week
€34.50
-
Hydrating Toner
Paula's Choice Skin Balancing Pore-Reducing Toner
Morning · Once a week
€36.00
-
Moisturizer
Dramatically Different Moisturizing Gel
Morning · Evening · Once a week
€24.46
-
Pre-Cleanser
Take The Day Off Cleansing Balm
Evening · Once a week
€22.53
-
Cleansing Toner
Clarifying Lotion 2
Evening
€34.39
-
Serum or Treatment
Smart Clinical Repair Wrinkle Correcting Serum
Evening · Once a week
€71.30
-
Enzyme Powder
Dermalogica Daily Microfoliant
Once a week
€48.55
-
Cleansing Mask
Origins Original Skin Retexturizing Mask with Rose Clay
Once a week
€28.50
Questions and answers
Cetaphil or Clinique: which is better?
Cetaphil is generally better for gentle hydration and sensitive skin, as the products on this page achieve a High routine fit across all main skin types compared to Clinique's average fit for several categories. Reviewers report that Cetaphil is more gentle on sensitive skin and offers superior moisture, whereas Clinique is often noted for a higher price point.
What is the difference between Cetaphil and Clinique?
Cetaphil is better for gentle, hydrating care with a lower price point, while Clinique excels at smoothing skin texture, exfoliation, and working well under makeup. For dry skin, the routine fit is High for Cetaphil and Average for Clinique.
Cetaphil or Clinique for dry skin?
Cetaphil is a better fit than Clinique for dry skin, as Cetaphil achieves a High routine fit level compared to Clinique's Average routine fit level. Reviewers on the page indicate that Cetaphil provides better hydration and moisture, and is more gentle on sensitive skin.
Cetaphil or Clinique: which cleanser is better?
Cetaphil is generally better for gentle cleansing, as reviewers mostly mention its cleansers are gentle and non-stripping, whereas reviewers note that Clinique's cleansers can cause issues like a lack of lather. The products on this page for Cetaphil achieve a High routine fit for sensitive skin, while Clinique's all about clean cleanser receives a Low fit for most skin types.
Which is more affordable, Cetaphil or Clinique?
Cetaphil is more affordable than Clinique, as high price points are noted as a drawback for Clinique products on this page.
Cetaphil or Clinique: which is better for mature skin?
Cetaphil is better for mature skin on this page, achieving a High routine fit compared to Clinique's Average fit. Reviewers also mention that Cetaphil does better on hydration, moisture, and being gentle on sensitive skin.
Which brand performs better regarding hydration and moisture according to reviewers?
Cetaphil performs better regarding hydration and moisture according to reviewers.
Cetaphil or Clinique for oily skin?
Both brands are a High fit for oily skin on the products on this page. Reviewers note that Clinique offers oil-controlling and smoothing moisturizers, while Cetaphil features oil-focused cleansers.
Cetaphil or Clinique: which moisturizer is better?
Cetaphil is generally better for hydration, offering High routine fit for dry skin compared to Clinique's Average fit. The products on this page help maintain moisture with ingredients like glycerin and hyaluronic acid.
Cetaphil or Clinique: which is better for skin with dark spots?
Cetaphil is better for skin with dark spots, as the routine fit on this page is High compared to Clinique's Average fit. Furthermore, the products on this page include niacinamide, which helps reduce cutaneous pigmentation.
Cetaphil or Clinique for sensitive skin?
Both Cetaphil and Clinique are good options for sensitive skin, as both brands achieve a High routine fit level. Reviewers note that Cetaphil stands out for being especially gentle on sensitive skin.
Cetaphil or Clinique for acne-prone skin?
Cetaphil fits acne-prone skin better, achieving a High routine fit compared to Clinique's Average routine fit on the products on this page.
Research behind their key ingredients
Effects of menthol and cold on histamine-induced itch and skin reactions in man
Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo
Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin
Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin
Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Colloidal Oatmeal <em>(Avena Sativa)</em> Improves Skin Barrier Through Multi-Therapy Activity
The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging
The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome
Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects
Algae extract protection effect on oxidized protein level in human stratum corneum
Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol
Modulating effects of oatmeal extracts in the sodium lauryl sulfate skin irritancy model
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects
Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery
Functional properties and skin care effects of sodium trehalose sulfate
Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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