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Vitamin C and palmitoyl tripeptide-1

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Vitamin C and palmitoyl tripeptide-1: depends on the strength

Depends on the strength

Apply vitamin C in the morning and palmitoyl tripeptide-1 at night, because copper complexes can oxidize ascorbate and reduce peptide efficacy. Copper acts as an oxidation catalyst that can diminish the benefits of your vitamin C and peptides. You can separate the two products into different routines or use chelating agents like EDTA.

Microneedle-Mediated Delivery of Copper Peptide Through Skin

Vitamin C products

Palmitoyl tripeptide-1 products

Questions and answers

Can you use vitamin C and palmitoyl tripeptide-1 together?

Yes, you can use vitamin C and palmitoyl tripeptide-1 together depending on the strength. Palmitoyl tripeptide-1 pairs well with vitamin C when using stabilized systems or specific products like Image Skincare the MAX Stem Cell Serum and No7 Protect & Perfect Intense Advanced Day Cream. Topical vitamin C effectively treats uneven and wrinkled skin while providing depigmenting properties in patients with melasma and photoaging.

Which goes first, vitamin C or palmitoyl tripeptide-1?

You should use vitamin C and palmitoyl tripeptide-1 in separate routines or choose compatible pH-tolerant peptide products like Image Skincare the MAX Stem Cell Serum and No7 Protect & Perfect Intense Advanced Day Cream to avoid reducing peptide efficacy. Vitamin C helps improve wrinkles and uneven skin tone.

Experimental Dermatology, 2003Journal of Cosmetic Dermatology, 2020

Are vitamin C and palmitoyl tripeptide-1 good for sensitive skin?

Yes, vitamin C and palmitoyl tripeptide-1 work well together depending on the strength, and you can find both ingredients in products like Image Skincare the MAX Stem Cell Serum and No7 Protect & Perfect Intense Advanced Day Cream. Vitamin C helps improve uneven and wrinkled skin while providing depigmenting properties.

Research on vitamin C and palmitoyl tripeptide-1

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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