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Vitamin A and palmitoyl tripeptide-1

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Vitamin A and palmitoyl tripeptide-1: keep them apart

Keep them apart

Use them at different times of day by applying vitamin A at night and palmitoyl tripeptide-1 in the morning to prevent extra skin irritation. Both active ingredients push your skin to renew itself quickly, which can easily lead to redness and sensitivity when used together. You can fix this by using a gentler vitamin A product or simply keeping them in separate daily routines.

Vitamin A products

Palmitoyl tripeptide-1 products

Questions and answers

Can you use vitamin A and palmitoyl tripeptide-1 together?

No, you should keep vitamin A and palmitoyl tripeptide-1 apart in your routine because combined stimulation may increase irritation, though you can use the retinoid at night and peptides in the morning. Mary Kay Timewise Night Solution contains both ingredients.

Which goes first, vitamin A or palmitoyl tripeptide-1?

Keep vitamin A and palmitoyl tripeptide-1 apart by using them at different times of day, such as your retinoid at night and peptides in the morning. Combining them in the same routine may increase your risk of skin irritation.

Are vitamin A and palmitoyl tripeptide-1 good for sensitive skin?

Vitamin A and palmitoyl tripeptide-1 should be kept apart to avoid increased irritation on sensitive skin, so use them at different times like PM retinoid and AM peptides. You may find them together in finished products like Mary Kay Timewise Night Solution.

Research on vitamin A and palmitoyl tripeptide-1

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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