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Advanced Clinicals skincare

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Advanced Clinicals is an American skincare brand founded in 2005 and owned by Concept Laboratories, Inc..

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Advanced Clinicals is widely loved for its thoughtful moisturizers and serums, relying on effective formulas. Its products suit dry, oily, combination, and sensitive skin best, as these formulas adapt easily to various needs. For distinct concerns, the brand offers standout options including the Vitamin C Brightening Gel-Cream for acne-prone skin, the Vitamin C Anti Aging Serum for skin with dark spots, and the Retinol Advanced Firming Cream for mature skin.

This page covers some of the most popular Advanced Clinicals products; for the whole Advanced Clinicals range, with a fit score for every product, use the Lovi app.

Other Advanced Clinicals products

People Say

★4.6Overall rating based on 232.7k+ reviews

Reviewers most often praise Advanced Clinicals for enhancing skin texture, deep hydration, and diminishing fine lines. The most common complaints are a drying or dehydrating effect and a slightly sticky finish.

Highlights

  • Great value Mostly Mentioned
    • “huge bottle for the price — Vitamin C Anti Aging Serum”
    • “Amazing quality for the price — Retinol Advanced Firming Cream”
    • “Great value for the size — Collagen Skin Rescue Lotion”
  • Improved skin texture and tone Mostly Mentioned
    • “noticeably lightened age spots — Vitamin C Anti Aging Serum”
    • “My skin feels firmer, smoother, and well-hydrated — Retinol Advanced Firming Cream”
    • “reducing the appearance of my laugh lines — HYALURONIC SERUM”
  • Deeply hydrating moisturizers Mostly Mentioned
    • “Instantly quenches thirsty skin — Collagen Skin Rescue Lotion”
    • “instant hydration for dry skin — HYALURONIC SERUM”
  • Fast-absorbing serums Mostly Mentioned
    • “Absorbs quickly and feels non-greasy — Retinol Advanced Firming Cream”
    • “absorbs quickly — Vitamin C Anti Aging Serum”
  • Fast-absorbing moisturizers Mostly Mentioned
    • “Absorbs quickly — Collagen Skin Rescue Lotion”
    • “absorbs well — HYALURONIC SERUM”
  • Fragrance-free formulas Often Mentioned
    • “It's fragrance-free, gentle even with retinol — Retinol Advanced Firming Cream”
    • “No added scent — Collagen Skin Rescue Lotion”
  • Skin dryness and irritation Often Mentioned
    • “My skin immediately feels dry like it feels dehydrated — Retinol Advanced Firming Cream”
    • “Caused minor breakout — Collagen Skin Rescue Lotion”
    • “dried out my skin — Vitamin C Anti Aging Serum”
  • Slightly sticky finish Often Mentioned
    • “It's a little sticky but It absorbs well. — HYALURONIC SERUM”
    • “leaves a sticky residue — Vitamin C Anti Aging Serum”

Sources: lovi.care, iherb.com, walmart.com, retinol.com, gopicky.com, amazon.com, and more

Questions and answers

Is Advanced Clinicals worth it?

Advanced Clinicals offers great value and deep hydration, making the brand worth considering for many shoppers. Lovi rates the Advanced Clinicals-focused routine Superior for dry skin, oily skin, sensitive skin, combination skin, and acne-prone skin. Reviewers often mention that the Advanced Clinicals products on this page are fragrance-free, though some users note skin dryness and irritation or a slightly sticky finish.

What are Advanced Clinicals's best products?

Advanced Clinicals's best products are the Vitamin C Brightening Gel-Cream, which Lovi rates High for dry and sensitive skin, and the HYALURONIC SERUM, which receives an Average fit across all skin types. Reviewers often mention that these formulas are fragrance-free and provide great value, though some users report skin dryness and irritation.

Which Advanced Clinicals moisturizer is best for dry skin?

The Vitamin C Brightening Gel-Cream is the best choice for dry skin, where Lovi rates it High. The Collagen Skin Rescue Lotion and HYALURONIC SERUM are also available options, with both rated Average for dry skin.

Journal of Cosmetic Dermatology, 2020Journal of the American Academy of Dermatology, 2008

Does Advanced Clinicals cause breakouts?

Advanced Clinicals is unlikely to cause breakouts, as the Advanced Clinicals products on this page are fragrance-free and the brand offers fast-absorbing serums and moisturizers that reviewers often praise. Lovi rates the Advanced Clinicals acne-prone routine Superior for acne-prone skin.

Is Advanced Clinicals fragrance-free?

Yes, every product from Advanced Clinicals on this page lists no fragrance in its ingredients. Reviewers often mention that these formulas are fragrance-free.

What are the key ingredients in Advanced Clinicals products?

Advanced Clinicals products feature key ingredients such as retinol, vitamin C, and green tea extract that help smooth skin and protect against everyday damage. Retinol helps reduce signs of aging and supports collagen buildup, while vitamin C brightens the complexion.

The Journal of Investigative Dermatology, 2000Archives of Dermatology, 2007

How do I build a Advanced Clinicals skincare routine?

To build an Advanced Clinicals skincare routine, start with a cleanser, then apply a fast-absorbing serum like the Vitamin C Anti Aging Serum, and finish with a deeply hydrating moisturizer such as the Collagen Skin Rescue Lotion. Lovi rates the Advanced Clinicals-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin.

What are good alternatives to Advanced Clinicals?

Good alternatives to Advanced Clinicals include brands with pages on Lovi like CeraVe, Cetaphil, Paula's Choice, Neutrogena, Kiehl's, and Dermalogica. For dry skin, Lovi rates the CeraVe-focused routine High while the Advanced Clinicals-focused routine is Superior.

Advanced Clinicals vs CeraVe: which is better?

Advanced Clinicals rates Superior for dry skin, oily skin, sensitive skin, combination skin, and acne-prone skin, whereas CeraVe rates High for dry skin and Superior for the others. Reviewers often mention that the Advanced Clinicals products on this page are fragrance-free, though some note skin dryness and irritation.

Who owns Advanced Clinicals, and where is it from?

Advanced Clinicals is an American brand founded in 2005, owned by Concept Laboratories, Inc..

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Is Advanced Clinicals cruelty-free?

PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list Advanced Clinicals as cruelty-free.

Research behind Advanced Clinicals's key ingredients

Behind these ratings

Lovi rates every product from its full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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