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Advanced Clinicals skincare

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Advanced Clinicals is an American skincare brand founded in 2005 and owned by Concept Laboratories, Inc..

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Advanced Clinicals is widely loved for its thoughtful moisturizers and serums, relying on effective formulas. Its products suit dry, oily, combination, and sensitive skin best, as these formulas adapt easily to various needs. For distinct concerns, the brand offers standout options including the Vitamin C Brightening Gel-Cream for acne-prone skin, the Vitamin C Anti Aging Serum for skin with dark spots, and the Retinol Advanced Firming Cream for mature skin.

This page covers some of the most popular Advanced Clinicals products; for the whole Advanced Clinicals range, with a fit score for every product, use the Lovi app.

Other Advanced Clinicals products

People Say

★4.6Overall rating based on 232.7k+ reviews

Reviewers most often praise Advanced Clinicals for enhancing skin texture, deep hydration, and diminishing fine lines. The most common complaints are a drying or dehydrating effect and a slightly sticky finish.

Highlights

  • Great value Mostly Mentioned
    • “huge bottle for the price — Vitamin C Anti Aging Serum”
    • “Amazing quality for the price — Retinol Advanced Firming Cream”
    • “Great value for the size — Collagen Skin Rescue Lotion”
  • Improved skin texture and tone Mostly Mentioned
    • “noticeably lightened age spots — Vitamin C Anti Aging Serum”
    • “My skin feels firmer, smoother, and well-hydrated — Retinol Advanced Firming Cream”
    • “reducing the appearance of my laugh lines — HYALURONIC SERUM”
  • Deeply hydrating moisturizers Mostly Mentioned
    • “Instantly quenches thirsty skin — Collagen Skin Rescue Lotion”
    • “instant hydration for dry skin — HYALURONIC SERUM”
  • Fast-absorbing serums Mostly Mentioned
    • “Absorbs quickly and feels non-greasy — Retinol Advanced Firming Cream”
    • “absorbs quickly — Vitamin C Anti Aging Serum”
  • Fast-absorbing moisturizers Mostly Mentioned
    • “Absorbs quickly — Collagen Skin Rescue Lotion”
    • “absorbs well — HYALURONIC SERUM”
  • Fragrance-free formulas Often Mentioned
    • “It's fragrance-free, gentle even with retinol — Retinol Advanced Firming Cream”
    • “No added scent — Collagen Skin Rescue Lotion”
  • Skin dryness and irritation Often Mentioned
    • “My skin immediately feels dry like it feels dehydrated — Retinol Advanced Firming Cream”
    • “Caused minor breakout — Collagen Skin Rescue Lotion”
    • “dried out my skin — Vitamin C Anti Aging Serum”
  • Slightly sticky finish Often Mentioned
    • “It's a little sticky but It absorbs well. — HYALURONIC SERUM”
    • “leaves a sticky residue — Vitamin C Anti Aging Serum”

Sources: lovi.care, iherb.com, walmart.com, retinol.com, gopicky.com, amazon.com, and more

Questions and answers

Is Advanced Clinicals worth it?

Yes, Advanced Clinicals is worth it, offering great value and effective moisturizers and serums that help improve skin texture. Lovi rates the Advanced Clinicals-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin.

What are Advanced Clinicals's best products?

Advanced Clinicals's best products are the Vitamin C Brightening Gel-Cream and Vitamin C Anti Aging Serum, as Lovi rates them High for skin with dark spots and mature skin. Reviewers also frequently mention that these moisturizers provide deep hydration and leave skin smooth. The Advanced Clinicals products on this page are fragrance-free.

Journal of Cosmetic Dermatology, 2020Journal of the American Academy of Dermatology, 2008

Which Advanced Clinicals moisturizer is best for dry skin?

The Vitamin C Brightening Gel-Cream is the best moisturizer on this page for dry skin, where Lovi rates it High. The Collagen Skin Rescue Lotion and HYALURONIC SERUM are also available options, and Lovi rates both as Average for dry skin.

Does Advanced Clinicals cause breakouts?

Advanced Clinicals is unlikely to cause breakouts when shoppers choose products suited to their skin type, as the Advanced Clinicals products on this page have fragrance-free formulas. Reviewers note that the line offers fast-absorbing serums and moisturizers, though some mention occasional skin dryness and irritation.

Is Advanced Clinicals fragrance-free?

Yes, every one of the Advanced Clinicals products on this page lists no fragrance in its ingredients. Reviewers often mention that these are fragrance-free formulas.

What are the key ingredients in Advanced Clinicals products?

Advanced Clinicals products feature key ingredients such as retinol, vitamin C, and plant extracts like green tea and chamomile. Retinol helps improve aged skin and smooth texture, while vitamin C and antioxidants brighten dark spots and protect against damage.

The Journal of Investigative Dermatology, 2000Journal of Cosmetic Dermatology, 2020

How do I build a Advanced Clinicals skincare routine?

To build an Advanced Clinicals routine, start with a fast-absorbing serum like the Vitamin C Anti Aging Serum or HYALURONIC SERUM, then follow with a deeply hydrating moisturizer such as the Vitamin C Brightening Gel-Cream or Collagen Skin Rescue Lotion. Lovi rates the Advanced Clinicals-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin types.

What are good alternatives to Advanced Clinicals?

Good alternatives to Advanced Clinicals include CeraVe, Cetaphil, Paula's Choice, Neutrogena, Kiehl's, and Dermalogica. These brands also offer skincare options that may fit various skin types.

Advanced Clinicals vs CeraVe: which is better?

Advanced Clinicals rates Superior for dry, oily, sensitive, combination, and acne-prone skin, while CeraVe rates High for dry skin and Superior for the others. Reviewers mention that the Advanced Clinicals products on this page offer great value and help improve texture and tone, although some note mild dryness or irritation.

Who owns Advanced Clinicals, and where is it from?

Advanced Clinicals is an American brand founded in 2005, owned by Concept Laboratories, Inc..

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Is Advanced Clinicals cruelty-free?

PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list Advanced Clinicals as cruelty-free.

Research behind Advanced Clinicals's key ingredients

Behind these ratings

Lovi rates every product from its full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

How does it fit your skin?

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