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Potassium hydroxide and hexapeptide-9

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Potassium hydroxide and hexapeptide-9: keep them apart

Keep them apart

Use them at different times of day with the peptide first, because high alkalinity ruins the peptide. Potassium hydroxide makes the environment too basic, which breaks down the peptide and stops it from firming your skin. You can wait a while between applying them or use them on separate days.

Potassium hydroxide products

Hexapeptide-9 products

Questions and answers

Can you use potassium hydroxide and hexapeptide-9 together?

No, you should keep potassium hydroxide and hexapeptide-9 apart in your routine because highly alkaline environments cause peptides to lose their stability and activity.

Which goes first, potassium hydroxide or hexapeptide-9?

Potassium hydroxide and hexapeptide-9 should be kept apart in your routine because highly alkaline environments cause peptides to lose their stability and activity. Apply them at different times of day to ensure both ingredients work effectively.

Are potassium hydroxide and hexapeptide-9 good for sensitive skin?

Potassium hydroxide and hexapeptide-9 should be kept apart in your routine because highly alkaline environments cause peptides to lose their stability and activity.

Research on potassium hydroxide and hexapeptide-9

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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