Principia Gel de Limpeza GL-01 for dry skin

How to apply

Questions and answers

What the research says

• Treatment with sodium lauryl ether sulfate emulsion increased transepidermal water loss and skin surface pH while reducing stratum corneum hydration and natural moisturizing factor content compared to diacyl phospholipid emulsions and controls, irrespective of UVA irradiation, in eight healthy volunteers.

  International Journal of Pharmaceutics, 2026

• Squamometry successfully detected subclinical skin surface alterations and discriminated between the irritating effects of sodium lauryl sulfate and sodium laureth sulfate on human skin using an open assay model.

  Food and Chemical Toxicology, 2001

• Skin irritation potential of surfactant mixtures in 13 human subjects was dose dependent, with the highest irritation observed in formulations containing sodium laureth sulfate, lauryl glucoside, and cocamide DEA together.

  International Journal of Cosmetic Science, 1999

• Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients.

  CMAJ, 2010

• A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase.

  BioMed Research International, 2020

• Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy.

  Journal of Cosmetic Dermatology, 2024

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• The cytotoxic effect of sodium lauryl sulphate on normal human keratinocytes was significantly decreased when combined with cocamidopropyl betaine, Tween 20, and Tween 80 at concentrations well below the critical micelle concentration.

  Skin Pharmacology and Applied Skin Physiology, 2003

• Coadministration of 40% topical L-menthol with 10% trans-cinnamaldehyde reduced spontaneous pain intensity, neurogenic inflammation, primary and secondary mechanical hyperalgesia, and heat hyperalgesia, but not cold hyperalgesia, in 14 healthy volunteers.

  The Journal of Pain, 2016

• Topical application of menthol-based cooling gel decreased intramuscular temperature by 1.9 °C and increased cutaneous blood flow by 0.3 ml/min in healthy males compared to placebo gel.

  International Journal of Sports Physical Therapy, 2018

• Cooling skin temperature or applying topical menthol reduced histamine-induced itch intensity and flare diameters in healthy male volunteers.

  Neuroscience Letters, 1995

Ingredients

Water, Salicylic Acid, Sodium Gluconate, Sodium Laureth Sulfate, Decyl Glucoside, Cocamidopropyl Betaine, Coco-Glucoside, Glyceryl Oleate, Sorbeth-450 Tristearate, Peg-9 Cocoate, Peg-32 Distearate, Peg-175 Distearate, Phenoxyethanol, Caprylyl Glycol, Menthol, Sodium Hydroxide

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.