NIOD Modulating Glucosides for oily acne-prone skin
Glucosides
Squalane
Superoxide Dismutase
Epigallocatechin Gallatyl Glucoside
Palmitoyl Tripeptide-8
High
- HighOily Skin Fit
- HighEffectiveness
- HighSafety
A great choice for oily acne-prone skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your oily skin, this formula leverages Epigallocatechin Gallatyl Glucoside and Rosmarinyl Glucoside to provide antioxidant and anti-inflammatory benefits, effectively addressing oiliness and breakouts.
- The inclusion of Bisabolol and Tasmannia Lanceolata Leaf Extract Fruit further enhances its soothing capabilities, making it a great choice for calming irritated skin.
- This product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.
How to apply
- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
People Say
★4.8Overall rating based on 400+ reviewsThis serum is highly praised for its ability to calm sensitive, reactive, and irritated skin, with users frequently reporting significant improvements in redness, stinging, and compromised skin barriers. It is a popular choice for those recovering from aesthetic treatments or harsh active ingredients. Some users with normal skin may find the benefits less noticeable or the texture slightly heavy.
Highlights
Calms sensitive skin Mostly Mentioned
- “Like medicine to irritated skin.”
- “Great for sensitive, reactive skin.”
- “Helps quiet sensations of stinging and itching.”
Reduces skin redness Often Mentioned
- “Visibly reduced redness for a more even tone.”
- “Calms redness and stinging.”
- “It really did wonders in soothing skin and reducing redness.”
Buffers active irritation Sometimes Noted
- “Helps minimise the side effects of retinoids.”
- “Buffers retinoid/acid irritation.”
- “Reason my skin had been so calm while I was on Roaccutane.”
Strengthens skin barrier Sometimes Noted
- “Saved my skin barrier from beyond hope.”
- “Strengthens skin barrier integrity over time.”
- “Especially helpful when my barrier is compromised.”
Inconvenient packaging Sometimes Noted
- “Dropper bottle is messy to use.”
- “Not my favorite type of packaging.”
- “Why doesn't it come with a pump?”
Subtle for normal skin Sometimes Noted
- “If you have normal skin, benefits may not be apparent.”
- “I did not notice any improvement.”
Can cause breakouts Rarely Noted
- “It broke me out almost instantly.”
- “Heavy going on my face.”
Unappealing scent Rarely Noted
- “Strong nutty scent.”
- “A bit like paint.”
- “Has a bit of a medicinal smell.”
Sources: lovi.care, niod.com, skinsort.com, dermapproved.com, drrachelho.com, daniellesbeautyblog.com, and more
Questions and answers
What makes NIOD Modulating Glucosides a great fit for oily acne-prone skin?
This treatment is a great fit because it uses specific plant-derived ingredients to calm redness and help keep breakouts under control. It is very gentle on oily skin and uses soothing components like bisabolol to help keep the skin feeling calm and comfortable.
Which ingredients make this treatment a good fit for oily acne-prone skin?
This treatment is a great fit for your oily skin because it uses Epigallocatechin Gallatyl Glucoside and Rosmarinyl Glucoside to calm breakouts and control oiliness. Ingredients like Bisabolol and Tasmannia Lanceolata Leaf Extract Fruit also help soothe irritated skin without adding heavy oils.
What do Glucosides do for oily acne-prone skin?
Glucosides act as gentle cleansers that help lift away dirt and excess oil without leaving your face dry or tight. They are generally well tolerated and unlikely to clog pores, making them a safe choice for keeping acne-prone skin clean and calm.
What does Squalane do for oily acne-prone skin?
Squalane may help keep oily skin soft and smooth, but oxidized squalene can trigger inflammation in acne-prone skin. Because of this, oily acne-prone skin needs lightweight, non-greasy ingredients that balance moisture without clogging pores.
Where does this treatment go in a skincare routine for oily acne-prone skin?
This treatment goes in your evening routine, applied after cleansing and before your moisturizer. Using it at night provides extra safety around sun exposure, while soothing components help calm irritated skin.
Can I use this treatment with retinol, and in what order?
You can use this treatment with retinol by applying the treatment first to help calm your skin, and then following with retinol. This helps reduce irritation while you treat breakouts.
How often should I use this treatment?
This treatment is used in the evening, applying it as part of your nighttime routine. It helps calm irritated skin and manage breakouts safely without harsh ingredients.
Can this treatment clog pores, cause breakouts or purging for oily acne-prone skin?
This treatment is a great fit for oily, acne-prone skin because it uses soothing ingredients like bisabolol and calming plant extracts to help keep breakouts and irritation at bay. While it is unlikely to clog pores or cause purging, reviewers occasionally mention a low chance of breakouts.
Is this treatment fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (benzyl alcohol).
What the research says
Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control.
European Journal of Pharmaceutics and Biopharmaceutics, 2016Topical treatment with the synthetic SOD/catalase mimetic EUK-134 reduced lipid peroxide levels both at baseline on non-irradiated human skin and at the surface of UVA-exposed skin when applied before or after irradiation, compared to controls.
International Journal of Cosmetic Science, 2004Topical superoxide dismutase formulations maintained physical stability and enzymatic activity for 6 months at 4 and 30 degrees C, and effectively inhibited UVB-induced skin erythema for 48 hours, whereas formulations combined with alpha-tocopherol were unstable.
European Journal of Pharmaceutics and Biopharmaceutics, 2007Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction.
Journal of Clinical and Diagnostic Research, 2017Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo.
Experimental Dermatology, 2009An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne.
Clinical, Cosmetic and Investigational Dermatology, 2019
Ingredients
Water, Squalane, Isodecyl Neopentanoate, Glycerin, Caprylic Capric Triglyceride, Pentylene Glycol, Propanediol, Hexyldecanol, Bisabolol, Butylene Glycol, Epigallocatechin Gallatyl Glucoside, Rosmarinyl Glucoside, Caffeyl Glucoside, Gallyl Glucoside, Tetrasodium Tetracarboxymethyl Naringeninchalcone, Hydroxymethoxyphenyl Decanone, 4-T-Butylcyclohexanol, Cetylhydroxyproline Palmitamide, Hydroxyphenyl Propamidobenzoic Acid, Palmitoyl Tripeptide-8, Superoxide Dismutase, Sodium Pca, Pca, Arginine, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Aspartic Acid, Sodium Lactate, Mirabilis Jalapa Callus Extract, Tasmannia Lanceolata Leaf Extract Fruit, Zingiber Officinale Root Extract, Curculigo Orchioides Root Extract, Isochrysis Galbana Extract, Brassica Campestris Sterols, Stearic Acid, Dextran, Isoceteth-20, Polyacrylate Crosspolymer-6, Xanthan Gum, Tocopherol, Propyl Gallate, Tromethamine, Dehydroacetic Acid, 1,2-Hexanediol, Benzyl Alcohol, Phenoxyethanol, Caprylyl Glycol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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