Cetaphil Gentle Makeup Removing Wipes for mature skin
High
- HighNormal Skin Fit
- HighEffectiveness
- ExcellentSafety
A great choice for mature skin; a few pre-cleansers fit it even better.
- Clinical, Cosmetic and Investigational Dermatology, 2017
- International Journal of Molecular Medicine, 2016
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your normal skin, these wipes effectively remove makeup with isohexadecane and glycerin, which also provide essential hydration. Aloe and chamomile extracts offer soothing benefits, complementing your skin's needs.
- While supportive for fine lines and wrinkles through general hydration, the formula does not contain specialized ingredients to target these concerns directly.
- The product is safe for your skin, featuring a gentle formulation with soothing ingredients and no harsh or irritating components.
How to apply
- Use this makeup remover as part of your PM routine every evening. Start 3x/week and move to daily use as your skin feels comfortable.
- Apply this makeup remover before your regular cleanser and toner. It acts as the very first step to melt away makeup.
- Gently massage a small amount of the makeup remover over dry skin to dissolve makeup, then rinse with warm water. Avoid any harsh rubbing around your eyes.
- Apply this makeup remover directly onto dry skin to effectively break down stubborn makeup and impurities. There is no need to dampen your face beforehand.
- Do a patch test before your first use to ensure your skin reacts well. Avoid direct contact with your eyes while cleansing.
People Say
★4.6Overall rating based on 1.2k+ reviewsWhile they are highly effective for daily cleansing, some users with heavy or waterproof makeup report needing multiple wipes or a second cleanse to fully remove all residue.
Highlights
Gentle on skin Mostly Mentioned
- “Perfect for sensitive or easily irritated skin.”
- “Leaves my face feeling clean, refreshed, and comforted.”
Effective makeup removal Often Mentioned
- “Removes makeup effortlessly, even stubborn mascara.”
- “Effectively lift off stubborn waterproof and long-wear makeup.”
- “Gets rid of all that makeup even my waterproof eyeliner.”
Fragrance-free formula Sometimes Noted
- “Love that they're fragrance-free and don't irritate.”
- “Scent is not overpowering.”
- “No weird scent lingering on my face.”
Soft cloth texture Sometimes Noted
- “Wipes are soft and don't tug at the skin.”
- “Texture is soft and leaves my face feeling refreshed.”
- “Ultra soft cloths gentle enough for the most sensitive skin.”
Dries out quickly Sometimes Noted
- “Top wipe sometimes felt less moist than the others.”
- “Tend to dry out faster than other wipes.”
- “Packaging seal doesn't stick well after a while.”
Requires multiple wipes Sometimes Noted
- “I often had to use two wipes to feel like I got everything off.”
- “One isn't always enough.”
- “Took our tester using four of the wipes to fully cleanse.”
Burning sensation Rarely Noted
- “Skin starts to burn sooo badly.”
- “Caused severe burning.”
- “Sting around the eye area.”
Leaves residue Rarely Noted
- “Leaves residue or film on skin after use.”
- “Felt something on my skin... like a film that didn't fully absorb.”
- “Slight sticky residue.”
Sources: lovi.care, cetaphil.com, walmart.com, ulta.com, hometesterclub.com, amazon.com, and more
Questions and answers
What makes Cetaphil Gentle Makeup Removing Wipes a great fit for mature skin?
These wipes are a great fit because they use glycerin and isohexadecane to take off makeup while keeping your skin hydrated, and they include soothing aloe and chamomile. The formula is very safe and gentle, though it lacks specialized ingredients to directly target fine lines and wrinkles.
Which ingredients make this makeup remover a good fit for mature skin?
Glycerin and isohexadecane make these wipes a good fit for mature skin by helping to provide essential hydration. Aloe and chamomile extracts also help calm the skin, while vitamin E offers soothing benefits.
Clinical, Cosmetic and Investigational Dermatology, 2017Journal of Cosmetic Dermatology, 2020
What does Aloe Vera do for mature skin?
Aloe vera helps smooth out fine lines and wrinkles by supporting collagen production, keeping mature skin feeling soft and elastic. It is unlikely to cause irritation and may improve skin firmness over time.
What does Chamomile do for mature skin?
Chamomile helps smooth mature skin by reducing wrinkles, improving firmness, and keeping it soft and well-hydrated. It also has a strong safety profile and is unlikely to cause irritation while protecting against daily sun damage.
International Journal of Molecular Medicine, 2016Revista Latino-americana de Enfermagem, 2018
Where does this makeup remover go in a skincare routine for mature skin?
This makeup remover goes in the evening routine before your cleanser, and also as the first step of your weekly routine. It is a great fit for your mature skin because it gently removes makeup while adding essential hydration with glycerin and soothing your skin with aloe and chamomile.
Can I use this makeup remover with retinol, and in what order?
You can use this makeup remover in the evening before your cleanser and treatment, as its gentle and soothing formula is safe for your skin. It helps keep your skin hydrated, but mature skin using retinol also needs targeted anti-aging ingredients like peptides or retinoids to properly address fine lines and wrinkles.
How often should I use this makeup remover?
You can use this makeup remover in the evening as part of your daily routine, and also once a week during your weekly routine. It effectively removes makeup while keeping your skin hydrated and calm with a very safe and gentle formulation.
Can this makeup remover clog pores, cause breakouts or purging for mature skin?
This makeup remover is unlikely to clog pores, cause breakouts or cause purging, as its gentle and soothing formula has very safe suitability for your skin. It cleanses without harsh or irritating components that typically trigger breakouts.
Is this makeup remover fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Apigenin protects against UVA-induced cytotoxicity and senescence in normal human dermal fibroblasts, decreases MMP-1 expression, and when applied topically as a cream in human subjects, increases dermal density and elasticity while reducing fine wrinkle length, skin evenness, moisture content, and transepidermal water loss compared to control cream.
International Journal of Molecular Medicine, 2016Topical epigallocatechin-3-gallate application and zonal priming reduced scar thickness and VEGFA, decreased mast cells, increased M2 macrophages and hydration, and improved elasticity compared with placebo in human scars.
The Journal of Investigative Dermatology, 2019Alpha-tocopherol loaded nanostructured lipid carrier gel provided enhanced moisturizing and anti-aging properties in human volunteers over 12 weeks.
Journal of Cosmetic Dermatology, 2020A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use.
Journal of Cosmetic Dermatology, 2022A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.
Clinical Pharmacology, 2018Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief.
Plastic and Reconstructive Surgery, 2018Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo.
Journal of Alternative and Complementary Medicine, 2010Topical chamomile oil combined with a night splint significantly improved the symptomatic and functional status of patients with severe carpal tunnel syndrome compared to placebo, while electrodiagnostic parameters showed no significant changes.
Complementary Therapies in Clinical Practice, 2015German chamomile solution applied twice a day healed peristomal skin lesions significantly faster than once-a-day 1% hydrocortisone ointment in colostomy patients, with a mean healing time of 8.89 days versus 14.53 days.
Ostomy/wound Management, 2011Topical chamomile reduces the incidence and delays the occurrence of phlebitis due to amiodarone infusion in coronary care patients compared to a placebo of lanoline.
Journal of Integrative Medicine, 2017Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction.
Journal of Clinical and Diagnostic Research, 2017Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo.
Experimental Dermatology, 2009An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne.
Clinical, Cosmetic and Investigational Dermatology, 2019Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.
Journal of Cosmetic Dermatology, 2025Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.
Contemporary Clinical Trials Communications, 2021Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.
Journal of Cosmetic Dermatology, 2024Transgenic cucumber expressing poly-γ-glutamic acid synthesis genes increased water content by 6-14%, reduced water loss by 11-12%, decreased facial wrinkles and roughness by 19.58% and 24.97%, decreased skin melanin by 5.27%, and improved facial elasticity in human skin and zebrafish compared to controls.
International Journal of Biological Macromolecules, 2024Copper Oxide nanoparticles synthesized using cucumber extract exhibited antibacterial, antifungal, UV protection, and reactive-oxygen species inhibition properties with low cellular toxicity and skin-rejuvenating effects when incorporated into skin cream.
Endocrine, Metabolic & Immune Disorders Drug Targets, 2021Topical treatment with Holothuria parva extract gel showed significant wound contraction compared to the negative control in full-thickness wounded rats.
The International Journal of Lower Extremity Wounds, 2024
Ingredients
Water, Isohexadecane, Dicaprylyl Ether, Octyldodecyl Stearoyl Stearate, Hexylene Glycol, Aloe Barbadensis Leaf Juice, Cucumis Sativus Fruit Extract, Chamomilla Recutita Flower Extract Chamomile Flower Extract, Camellia Sinensis Leaf Extract, Tocopheryl Acetate Vitamin E, Centaurea Cyanus Flower Extract, Glycerin, Ethylhexyl Hydroxystearate, Lauryl Glucoside, Polyglyceryl-2 Dipolyhydroxystearate, Aminomethyl Propanol, Phenoxyethanol, Sorbitan Laurate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Iodopropynyl Butylcarbamate, Disodium Edta, Ethylene Brassylate, Citric Acid, Propylene Glycol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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