Murad Retinal ReSculpt Overnight Treatment for sensitive skin
Retinal
Squalane
Butyrospermum Parkii Butter Shea Butter
Avena Sativa Kernel Extract Oat Kernel Extract
UreaHigh
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
One of the best serums for sensitive skin.
This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for normal skin, this treatment utilizes retinal and urea to regulate desquamation and provide humectant action, supporting your skin's overall health.
- While it offers general hydration and soothing benefits from oat kernel extract and shea butter, it lacks specialized ingredients to directly target your redness and irritation concerns.
- The formulation is safe for your sensitive skin, containing no harsh ingredients and including soothing components.
How to apply
- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
People Say
★4.8Overall rating based on 600+ reviewsUsers report this treatment effectively targets advanced signs of aging, leading to visibly firmer, smoother, and bouncier skin. It is frequently praised for delivering results on deep wrinkles and sagging without the typical irritation associated with potent retinoids.
Highlights
Visibly smooths texture Mostly Mentioned
- “skin feels smooth and soft”
- “noticeably smoother to the touch”
- “improved texture after a few weeks”
Firms and lifts Often Mentioned
- “jawline seems more defined”
- “skin feels more taut”
- “helps with sagging neck skin”
Gentle and non-irritating Often Mentioned
- “no tingling or redness”
- “great for sensitive skin”
- “less irritating than prescription tretinoin”
High price point Often Mentioned
- “too expensive for the amount”
- “price tag is steep”
- “hard to justify the cost”
Fast-acting results Sometimes Noted
- “saw results in 2 weeks”
- “immediate glow the next morning”
- “works faster than retinol”
Pleasant consistency Sometimes Noted
- “lightweight and absorbs easily”
- “creamy but not greasy”
- “soaks in quickly”
Deceiving packaging Sometimes Noted
- “bottle looks big but holds little”
- “bulky plastic packaging”
- “hard to tell when empty”
Lack of results Rarely Noted
- “no difference in 2 months”
- “didn't do much for deep lines”
- “expected more for the price”
Scent/Fragrance Rarely Noted
- “has a floral scent”
- “added fragrance not listed”
- “smell is a bit strong”
Sources: lovi.care, ulta.com, murad.com, dermstore.com, lovelyskin.com, and more
Questions and answers
What makes Murad Retinal ReSculpt a great fit for sensitive skin?
Murad Retinal ReSculpt Overnight Treatment is a great fit because it is safe for sensitive skin, containing no harsh ingredients and including soothing components like oat kernel extract and shea butter. It helps keep your skin calm and smooth while supporting overall skin health without causing irritation.
Pharmaceutics, 2021Skin Pharmacology and Applied Skin Physiology, 2002
Which ingredients make this treatment a good fit for sensitive skin?
This treatment is a good fit for sensitive skin because it contains soothing oat kernel extract and shea butter alongside retinal and urea. These ingredients help calm dry skin while keeping it comfortable and well-hydrated.
What does Retinal do for sensitive skin?
Retinal helps smooth fine lines, improve texture, and even out skin tone while generally maintaining a good tolerance profile with a lower likelihood of irritation compared to stronger forms of vitamin A.
What does Squalane do for sensitive skin?
Squalane helps calm sensitive skin by defending against everyday irritation and keeping it smooth and soft. It is unlikely to cause irritation and supports your skin barrier so it stays comfortable and hydrated.
Where does this treatment go in a skincare routine for sensitive skin?
This treatment goes in the evening routine after your toner and before your moisturizer. Putting it at night helps keep your skin safe from extra sun exposure while it works.
Can I use this treatment with niacinamide, and in what order?
You can use this treatment alongside niacinamide by applying niacinamide first and letting it absorb before applying this treatment. This combination helps keep your skin calm while improving texture, though it may occasionally cause mild tingling if your skin is not used to active ingredients.
How often should I use this treatment?
Use this treatment in your evening routine, starting just once a week to see how your skin reacts. Because it contains active ingredients, you may slowly increase how often you use it if your skin tolerates it well without irritation.
Can this treatment clog pores, cause breakouts or purging for sensitive skin?
This treatment is unlikely to clog pores or cause breakouts for sensitive skin because it is formulated without harsh ingredients and includes soothing components. However, since it contains retinal, you may experience mild initial purging as your skin adjusts to the faster cell renewal.
Pharmaceutics, 2021Skin Pharmacology and Applied Skin Physiology, 2002
Is this treatment fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (citronellol and parfum). Cetearyl alcohol and cetyl alcohol are fatty alcohols, which soften the skin.
What the research says
Urea is a safe and effective dermatologic therapy with wide-ranging clinical utility for various skin conditions and minimal, non-systemic side effects based on a review of the clinical literature.
Dermatology Online Journal, 2013A multiple W/O/W emulsion containing Rosmarinus officinalis L., Avena sativa L., and Linum usitatissimum L. extracts showed no irritant, phototoxic, inflammatory, or allergenic potential in human skin models and patch tests, establishing its safety as a cosmetic base.
Pharmaceutics, 2021Topically applied Avena sativa and Avena Rhealba oatmeal extracts significantly reduced skin irritation parameters including a* parameter increase and blood flow increase compared to vehicle in 12 healthy individuals subjected to the sodium lauryl sulfate irritation model.
Skin Pharmacology and Applied Skin Physiology, 2002Twice daily application of retinaldehyde 0.1% and 0.05% creams for 3 months improved skin texture and hydration and reduced transepidermal water loss in 40 female Korean volunteers, with only the 0.1% cream significantly improving the melanin index.
Journal of Cosmetic Dermatology, 2018Topical retinaldehyde demonstrated significant antibacterial activity against gram-positive bacteria both in vitro and in vivo, leading to decreased bacterial counts without inducing resistance.
Dermatology, 2002Topical 0.05% retinaldehyde applied over 1 year significantly increased epidermal thickness of the temple and cutaneous elasticity compared to an emollient control group in 40 aging skin patients.
Dermatology, 1999Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.
Lasers in Medical Science, 2025A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.
International Journal of Cosmetic Science, 2025A repair cream containing Rhealba oat plantlets extract, l-ALA-l-GLU dipeptide, and hyaluronic acid provided immediate relief and was judged by doctors as good or very good in 96.8% of cases for wound healing in 2,363 patients following dermatological acts.
Clinical, Cosmetic and Investigational Dermatology, 2018Colloidal oat extracts diminished pro-inflammatory cytokines in vitro and colloidal oat lotion improved skin dryness, scaling, roughness, and itch intensity in healthy female subjects compared to baseline.
Journal of Drugs in Dermatology, 2015Colloidal oat increased the growth rate, metabolism, and lactic acid production of Staphylococcus epidermidis compared to Staphylococcus aureus in vitro, matching clinical increases in lactic acid on dry skin after 6 weeks of lotion use.
Clinical, Cosmetic and Investigational Dermatology, 2021Topical 40% urea cream achieved improvement in less time and showed superiority over 12% ammonium lactate lotion in skin roughness, fissure reduction, thickness, and dryness at day 14 in patients treated for moderate to severe xerosis.
American Journal of Clinical Dermatology, 2002Topical treatment with K101 achieved a significantly higher mycological cure rate compared to placebo in patients with ≤50% nail involvement (27.2% vs 10.4%), while showing early visible improvements in nail appearance and no safety issues.
Mycoses, 2012
Ingredients
Water, Diisostearyl Malate, Pentylene Glycol, Polyglyceryl-3 Methylglucose Distearate, Zea Mays Kernel Extract, Squalane, Propanediol, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Glycerin, Cetearyl Alcohol, Glyceryl Ricinoleate, Avena Sativa Kernel Extract Oat Kernel Extract, Butyrospermum Parkii Butter Shea Butter, Retinal, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Anigozanthos Flavidus Extract, Phosphatidylcholine, Olea Europaea Leaf Extract Olive Leaf Extract, Mannitol, Ethylhexylglycerin, Dimethyl Isosorbide, Glyceryl Stearate, Sodium Stearoyl Glutamate, Cetyl Alcohol, Hectorite, Xanthan Gum, Sodium Chloride, Polysorbate 60, Sorbitan Isostearate, Leuconostoc Radish Root Ferment Filtrate, Tetrasodium Glutamate Diacetate, Citric Acid, Sodium Benzoate, Chlorphenesin, Potassium Sorbate, Citronellol, Alpha-Isomethyl Ionone, Parfum
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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