Dr. Barbara Sturm Super Anti-Aging Serum for mature skin
Sodium Hyaluronate
Baicalin
Glutathione
Lactobacillus Portulaca Oleracea Extract FermentAverage
- HighNormal Skin Fit
- AverageEffectiveness
- ExcellentSafety
Works for mature skin; other serums fit it better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate anti-aging benefits for your normal skin, as glutathione and baicalin help minimize fine lines and wrinkles, while sodium hyaluronate and Lactobacillus Portulaca Oleracea Extract Ferment provide general hydration and barrier support.
- The formula is safe for your normal skin, with Lactobacillus Portulaca Oleracea Extract Ferment offering soothing properties and no harsh ingredients present.
- While providing good hydration and antioxidant benefits, the serum's specialized action for wrinkles and fine lines is limited, suggesting a need for more targeted ingredients to fully address your primary concerns.
How to apply
- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
People Say
★4.4Overall rating based on 500+ reviewsUsers frequently highlight the serum's elegant, non-sticky texture and its ability to provide immediate, deep hydration, leaving skin soothed and glowing. Many also appreciate its effectiveness in calming redness and plumping the skin. A significant number of reviewers, however, question the product's value, finding the high price point unjustified given the perceived lack of dramatic anti-aging results compared to more affordable options.
Highlights
Superior texture Mostly Mentioned
- “absorbs almost immediately”
- “leaves no residue”
- “silky but not pore-clogging”
- “glides across face”
Exorbitant price Mostly Mentioned
- “extremely expensive”
- “waste of money”
- “not worth the price tag”
- “ridiculously priced”
Deep hydration Often Mentioned
- “skin feels refreshed”
- “very hydrating and plumps”
- “cool drink of water”
- “relieves dry tight skin”
Calming and soothing Sometimes Noted
- “calmed down redness”
- “skin feels calmer”
- “good for sensitive skin”
- “reduced inflammation”
Radiance and glow Sometimes Noted
- “noticeably brighter”
- “gives baby soft skin”
- “youthful radiance”
- “skin looks healthy”
Lack of results Sometimes Noted
- “don't see any difference”
- “didn't achieve flawless skin”
- “no miracle results”
- “just a moisturizer”
Basic ingredients Rarely Noted
- “just a hyaluronic serum”
- “can get cheaper dupes”
- “paying for the brand”
- “basic ingredients list”
Sources: lovi.care, spacenk.com, sephora.com, nordstrom.com, cultbeauty.com, mecca.com, and more
Questions and answers
How well does Dr. Barbara Sturm Super Anti-Aging Serum work for mature skin?
This serum works moderately well for mature skin, providing basic hydration and soothing benefits while helping to soften fine lines. However, its specialized action for wrinkles is somewhat limited. A product for this skin needs high-quality ingredients that target fine lines effectively, improve skin elasticity, and include a rich mix of peptides and deep-hydrating agents.
Clinical, Cosmetic and Investigational Dermatology, 2014Journal of Cosmetic Dermatology, 2025
Which ingredients make this serum a good fit for mature skin?
Glutathione and baicalin help minimize fine lines and wrinkles, while sodium hyaluronate and Lactobacillus Portulaca Oleracea Extract Ferment provide general hydration and barrier support. To fully address mature skin concerns, a product of this type needs peptides, potent antioxidants, and skin-repairing ingredients that improve elasticity and moisture retention without irritation.
Clinical, Cosmetic and Investigational Dermatology, 2014Journal of Cosmetic Dermatology, 2025
What does Hyaluronic Acid do for mature skin?
Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Journal of Drugs in Dermatology, 2011Skin Research and Technology, 2024
What does Baicalin do for mature skin?
Baicalin helps smooth fine lines, improves firmness, and fights daily sun damage in mature skin. It works to reduce wrinkles and boost collagen production to keep skin looking bright and elastic.
Where does this serum go in a skincare routine for mature skin?
This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Because it offers only moderate anti-aging benefits for mature skin, a routine for this skin needs more targeted ingredients like retinoids or peptides to fully address fine lines and wrinkles.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol by applying the serum first to give your skin moisture and antioxidant benefits before layering your retinol. This product helps soften fine lines with glutathione and baicalin, but mature skin typically needs more targeted ingredients like peptides or stronger retinoids to fully address deep wrinkles.
Clinical, Cosmetic and Investigational Dermatology, 2014Journal of Cosmetic Dermatology, 2025
How often should I use this serum?
You can use this treatment in the evening as part of your routine. This timing keeps things simple and provides extra safety around sun exposure, though some treatments can also be used in the morning or twice a day.
Can this serum clog pores, cause breakouts or purging for mature skin?
This serum is unlikely to clog pores or cause breakouts for mature skin, as it has a gentle formula without harsh ingredients. However, to fully care for mature skin, this type of product needs stronger wrinkle-fighting ingredients and deep hydrators to smooth fine lines.
Is this serum fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2014Motor baicalin encapsulated in bio-vesicles enhanced water solubility, stability, transdermal penetration, antioxidant activity, and clinical skin antiaging efficacy compared to liposome baicalin and baicalin raw material.
Journal of Cosmetic Dermatology, 2025Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.
Journal of Cosmetic Dermatology, 2026Portulaca oleracea extract ameliorated skin barrier damage and inflammation induced by combined exposure to glycolic acid and UVB in HaCaT cells.
Cutaneous and Ocular Toxicology, 2022Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls.
Journal of the European Academy of Dermatology and Venereology, 2024Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019A nighttime topical antioxidant containing resveratrol, baicalin, and vitamin E significantly improved fine lines, wrinkles, firmness, elasticity, laxity, hyperpigmentation, radiance, roughness, and dermal thickness in subjects with mild to moderately photodamaged skin over 12 weeks.
Journal of Drugs in Dermatology, 2014Core-shell gellan-transfersomes loading baicalin achieved high skin deposition (~11% in whole skin, ~8% in dermis) and improved baicalin efficacy by providing complete skin restoration and inhibiting inflammatory markers in mice.
Nanomedicine, 2018Glycyrrhizin micellar nanocarriers significantly improved topical penetration and follicular accumulation of baicalin in porcine skin, enhanced human dermal papilla cell proliferation, and promoted hair recovery through Wnt/β-catenin pathway activation and upregulation of VEGF, α-MSH, and IL-10.
International Journal of Pharmaceutics, 2022Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity.
The Journal of Clinical and Aesthetic Dermatology, 2025RayGel reduced skin reaction severity with a lower average score of 93.7 compared to 123.3 for the placebo group in patients undergoing whole breast external-beam irradiation.
American Journal of Surgery, 2005Combining high-intensity focused ultrasound with a topical agent containing glutathione and hyaluronic acid significantly improves skin quality, fine wrinkles, hyperpigmentation, hydration, and brightness in female volunteers compared to the topical agent alone.
The Journal of Dermatological Treatment, 2024Topical purslane at 5% and 10% concentrations achieved alleviation of symptoms and lesion remission comparable to topical 0.1% triamcinolone acetonide in 34 subjects with oral lichen planus over 90 days.
BMC Oral Health, 2023Facial masks containing low-temperature extracted Portulaca oleracea protect sensitive skin from photothermal stimulation and improve skin barrier function during photorejuvenation.
Cutaneous and Ocular Toxicology, 2025Topical application of a crude extract of Portulaca oleracea accelerates wound healing by decreasing wound surface area and increasing tensile strength in Mus musculus JVI-1, with the greatest contraction achieved at a single dose of 50mg compared to other dosages.
Journal of Ethnopharmacology, 2003
Why other serums fit mature skin better
Caviar oil enhanced adipocyte differentiation in vitro, reduced MMP expression while increasing collagen and elastin formation ex vivo, and improved skin moisture, elasticity, and density in 102 participants over four weeks of Cavi Balm usage compared to baseline.
In Vivo, 2023Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.
Journal of Cosmetic Dermatology, 2026A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.
Journal of Cosmetic Dermatology, 2020
Ingredients
Water, Butylene Glycol, Lactobacillus Portulaca Oleracea Extract Ferment, Propanediol, Phenoxyethanol, Sodium Hyaluronate, Ethylhexylglycerin, Leuconostoc Radish Root Ferment Filtrate, Baicalin, Glutathione
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-
Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-
Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-
Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-
Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-
Medical Board
Cosmetic chemist, SCS, IFSCC member
-
Medical Board, Medical Advisor
Dermatology MD
-
Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-
Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.