Biossance Squalane + Ectoin Overnight Rescue for dry skin
Squalane
Ectoin
Glycerin
Shorea Stenoptera Seed Butter
Acetyl Hexapeptide-8
High
- HighDry Skin Fit
- HighEffectiveness
- ExcellentSafety
One of the best moisturizers for dry skin.
This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Highly suitable for your dry skin as squalane and glycerin provide excellent emollient and humectant actions to hydrate and support your skin barrier. Ectoin further enhances barrier resilience and offers protection against environmental stressors, addressing your dry or flaky skin concerns.
- The formulation includes Shorea Stenoptera Seed Butter and jojoba esters, which offer additional nourishment and emollience beneficial for dry skin.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components like Ectoin and Squalane.
How to apply
- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
People Say
★4.6Overall rating based on 2.0k+ reviewsMost users report waking up to soft, plump, and soothed skin without irritation. Those with oily or acne-prone skin occasionally find the formula too rich. This summary is based on a very large amount of data and should definitely be taken into account.
Highlights
Deeply hydrating Mostly Mentioned
- “My skin loves and drinks this right up.”
- “It keeps my face hydrated until morning.”
- “This is the first cream that has helped with my dry skin.”
- “Hydrates me very well overnight.”
Absorbs well Often Mentioned
- “Absorbs right in without the need to overly blend it in.”
- “It is not greasy at all like serums can be.”
- “Melts into your skin so easily and effortlessly.”
- “Absorbs quickly and leaves no greasy residue or film.”
Plumps and softens Often Mentioned
- “Wake up with plump, moisturized, healthy-looking skin.”
- “Makes my skin look super plump, glowing, and helps it to feel very soft.”
- “I wake up in the morning to baby smooth skin.”
- “Always makes my skin feeling so soft as soon as I put it on.”
Soothes sensitive skin Often Mentioned
- “There is no stinging, irritation or redness when using this product.”
- “I have very sensitive skin and this has been great for my skin.”
High price point Sometimes Noted
- “Seventy dollars for one small jar is a steep ask.”
- “Seventy dollars buys a single fifty-milliliter jar.”
- “Asks you to pay a premium.”
Heavy or greasy Rarely Noted
- “Consistency leaves a greasy feel to the skin.”
- “The overnight rescue is by far one of the thickest creams I have ever used.”
- “Heaviness, or a greasy feel may occur for some users.”
- “Oily and breakout-prone complexions will likely find it too rich.”
Jar packaging Rarely Noted
- “As always, a jar means scooping.”
- “Which is a small hygiene knock.”
- “The frosted glass jar is attractive but... a jar means scooping.”
May cause breakouts Rarely Noted
- “A few reviews mention that breakouts... may occur for some users.”
- “Not formulated to be fungal-acne safe.”
- “Oily and breakout-prone complexions will likely find it too rich.”
Sources: lovi.care, sephora.com, biossance.com, influenster.com, dermapproved.com, cultbeauty.co.uk, and more
Questions and answers
What makes Biossance Squalane + Ectoin Overnight Rescue a great fit for dry skin?
Biossance Squalane + Ectoin Overnight Rescue is a great fit because squalane, glycerin, and seed butter hydrate dry skin and support the skin barrier. Ectoin adds extra barrier protection against environmental stressors to help keep flaky skin calm and comfortable.
Which ingredients make this cream a good fit for dry skin?
Squalane, ectoin, glycerin, Shorea Stenoptera seed butter, and jojoba esters make this cream a great fit because they hydrate, nourish, and protect your dry skin while supporting your skin barrier. Ectoin and squalane also help ensure a very safe, soothing experience without any harsh irritation.
What does Squalane do for dry skin?
Squalane helps keep dry skin soft and smooth by acting as a hydrating agent that locks in moisture and prevents water loss. It is unlikely to cause irritation and may protect the skin from damage while improving overall hydration.
Advances in Food and Nutrition Research, 2012Molecules, 2009
What does Ectoin do for dry skin?
Ectoin helps dry skin by locking in moisture to keep it soft and smooth while strengthening the outer barrier to stop water from escaping. It may also calm redness and ease skin sensitivity.
Clinics in Dermatology, 2008European Journal of Dermatology, 2025
Where does this cream go in a skincare routine for dry skin?
This cream goes in the evening routine as a treatment step before your moisturizer, helping to lock in hydration and support your skin barrier. It is very gentle and unlikely to cause irritation on dry skin.
Can I use this cream with retinol, and in what order?
You can use this treatment with retinol by applying the treatment first and following it with your retinol, or by using the treatment in your morning routine and retinol at night. Using a barrier-enhancing moisturizer helps improve skin tolerance and reduces the irritation often caused by retinoids.
How often should I use this cream?
This moisturizing treatment is designed for evening use as part of your nightly routine for dry skin. Daily application helps lock in moisture, keeps dry or flaky skin smooth, and is unlikely to cause irritation.
Health Science Reports, 2021Journal of Cosmetic Dermatology, 2020
Can this cream clog pores, cause breakouts or purging for dry skin?
This cream is unlikely to cause breakouts on dry skin because it features soothing ingredients and a very low risk of clogged pores according to reviewers. It is designed to deeply hydrate and nourish dry skin without heavy or greasy side effects.
Can I use this cream around the eyes or on my body?
This cream is well-suited for the thin skin around the eyes and body because its gentle, nourishing formula keeps dry areas soft and hydrated. It has an excellent safety profile with soothing ingredients that are unlikely to cause irritation.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017Topical formulations containing 3.75% glycerol and 1.25% hydrolyzed jojoba esters produced significantly lower evaporative TEWL values compared to glycerol alone at 8 and 24 hours posttreatment in human subjects.
Journal of Cosmetic Dermatology, 2008Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.
Molecules, 2025Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.
Antioxidants, 2025Combining ectoine and mannitol with UV filters significantly improved protection of squalene oxidation, catalase activity, and trans-UCA compared to UV filters alone in 10 subjects on irradiated areas.
Journal of Cosmetic Dermatology, 2024Topical 7% ectoine during serial 1064-nm Nd:YAG laser therapy produced a greater reduction in skin erythema, improved stratum corneum hydration, reduced transepidermal water loss, and decreased low-echogenic pixels in thirty participants compared to a vehicle control.
Biomedicines, 2026Regular application of a novel anti-ageing cream containing hyaluronic acid, ectoin, and botanical actives significantly reduced wrinkle depth and length in the periorbital area while demonstrating very good skin tolerance.
Polymers, 2023The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.
Journal of Cosmetic Dermatology, 2020Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.
International Journal of Cosmetic Science, 2001Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.
Journal of Drugs in Dermatology, 2012Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days.
Annals of Dermatology, 2019Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group.
American Journal of Clinical Dermatology, 2013Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear.
Journal of Cosmetic Dermatology, 2017
Ingredients
Water, Glycerin, Squalane, Shorea Stenoptera Seed Butter, Caprylic Capric Triglyceride, C12-16 Alcohols, Sodium Acrylates Copolymer, Ectoin, Jojoba Esters, Acetyl Hexapeptide-8, Magnesium Chloride, Palmitic Acid, Hydrogenated Lecithin, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Lecithin, Sorbitan Isostearate, Tocopherol, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Sodium Gluconate
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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