Pro-retinol and hexapeptide-9
Keep them apart
Use them at different times of day by applying hexapeptide-9 in the morning and pro-retinol at night to avoid skin irritation. Both ingredients work hard to renew the skin, but using them together can cause redness and irritation. You can easily fix this by using a gentler formula or separating them into different daily routines.
All about pro-retinol
All about hexapeptide-9Pro-retinol products
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L'Oreal Paris
Revitalift
拢15.69
Hexapeptide-9 products
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Elemis
Pro-Collagen Night Cream
拢96.00
- Murad Cellular Hydration Repair Serum
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MARY & MAY
6 Peptide Complex Serum
拢12.76
Questions and answers
Can you use pro-retinol and hexapeptide-9 together?
No, you should keep pro-retinol and hexapeptide-9 apart in your routine because combining them may increase irritation. Try alternating their usage, such as applying your retinoid at night and peptides in the morning.
Which goes first, pro-retinol or hexapeptide-9?
Keep pro-retinol and hexapeptide-9 apart in your routine because combining them may increase irritation. Alternate their usage by applying hexapeptide-9 in the morning and pro-retinol at night.
Are pro-retinol and hexapeptide-9 good for sensitive skin?
Pro-retinol and hexapeptide-9 should be kept apart in your routine because combining them may increase irritation. Try alternating them by using your retinoid at night and peptides in the morning.
Research on pro-retinol and hexapeptide-9
Behind this pairing advice
Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sof铆a Perea P茅rez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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