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Niacinamide and retinoid blend

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Niacinamide and retinoid blend: depends on the strength

Depends on the strength

Use them at different times of day with niacinamide in the morning and retinoids at night, because mild retinoids pair well while strong ones can clash. Niacinamide calms redness and protects your skin, while retinoids speed up cell renewal, which can sometimes cause irritation when mixed. You can try a gentler product strength or wait longer between applying them if your skin feels sensitive.

Retinoids: a journey from the molecular structures and mechanisms of action to clinical uses in dermatology and adverse effectsWhy Topical Retinoids Are Mainstay of Therapy for Acne

Niacinamide products

Retinoid blend products

Questions and answers

Can you use niacinamide and retinoid blend together?

Yes, you can use niacinamide and low-strength or buffered retinoids together because niacinamide helps reduce irritation and redness. You may use niacinamide in the morning and retinol at night to keep your skin comfortable.

Which goes first, niacinamide or retinoid blend?

Whether niacinamide or a retinoid blend goes first depends on the strength of the retinoid. Low percentage, buffered retinoids can be used together with niacinamide to help reduce irritation and redness, while strong retinoids should be separated by using the retinoid at night and niacinamide in the morning.

Are niacinamide and retinoid blend good for sensitive skin?

Yes, low strengths of niacinamide and a retinoid blend are beneficial for sensitive skin because niacinamide helps reduce irritation and redness caused by retinoids. It is best to use niacinamide in the morning and retinol at night.

Research on niacinamide and retinoid blend

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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