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Niacinamide and mandelic acid

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Niacinamide and mandelic acid: depends on the strength

Depends on the strength

Apply mandelic acid and niacinamide at different times of day because strong acids can clash with niacinamide and cause skin flushing. Mandelic acid exfoliates while niacinamide calms and evens skin tone. You can use them in separate routines or wait thirty minutes between applying each product.

Niacinamide: A B vitamin that improves aging facial skin appearanceThe effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer

Niacinamide products

Mandelic acid products

Questions and answers

Can you use niacinamide and mandelic acid together?

You can use niacinamide and mandelic acid together depending on the strength, but it is best to avoid them in the same routine or separate them by at least 30 minutes to prevent irritation. Products like Vivant 8% Mandelic Acid Serum and Dermalogica PowerBright Dark Spot Peel contain both ingredients.

Which goes first, niacinamide or mandelic acid?

You should separate niacinamide and mandelic acid by at least thirty minutes or use them in different routines, because strong acids like mandelic acid have a low pH that can cause niacinamide to convert and irritate your skin.

Are niacinamide and mandelic acid good for sensitive skin?

Using niacinamide and mandelic acid together depends on the strength because strong acids can cause flushing and irritation, so you should separate them by at least 30 minutes or use them in different routines.

Research on niacinamide and mandelic acid

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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