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Mandelic acid and peptide-rich plasma

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Mandelic acid and peptide-rich plasma: keep them apart

Keep them apart

Use them at different times of day by applying mandelic acid in the morning and peptide-rich plasma at night, because acids ruin peptide strength. Mixing them makes the peptides less effective and wastes the benefits of the plasma. The shopper can change to applying them in separate routines or waiting longer between steps.

Mandelic acid products

Peptide-rich plasma products

Questions and answers

Can you use mandelic acid and peptide-rich plasma together?

Keep mandelic acid and peptide-rich plasma apart because the acidic environment of mandelic acid destabilizes peptide bonds and reduces their bioactivity. Use them in separate steps or routines, such as applying one in the morning and the other at night.

Which goes first, mandelic acid or peptide-rich plasma?

Keep mandelic acid and peptide-rich plasma apart by using them in separate steps or routines such as AM and PM separation. The low pH of mandelic acid destabilizes peptide bonds and may reduce their bioactivity.

Are mandelic acid and peptide-rich plasma good for sensitive skin?

Mandelic acid and peptide-rich plasma should be kept apart, especially on sensitive skin, because the low-pH acid destabilizes peptide bonds and reduces their bioactivity. Use them in separate steps or routines, such as AM and PM separation.

Research on mandelic acid and peptide-rich plasma

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sof铆a Perea P茅rez, MD, MSc

    Dr. Sof铆a Perea P茅rez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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