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Perricone MD Rejuvenating Moisturizer for oily acne-prone skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Perricone MD Rejuvenating Moisturizer

Average

  • AverageOily Skin Fit
  • AverageEffectiveness
  • Low RiskSafety

Works for oily acne-prone skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate suitability for your oily skin, as glycerin and dimethicone provide excellent hydration and smoothing without exacerbating oiliness.
  • While it addresses general hydration and soothing for your acne concerns with S-Palmitoylglutathione, it lacks specialized ingredients for directly combating blemishes.
  • The product is generally safe for your oily skin, though lactic acid and parfum carry a slight risk of irritation.

How to apply

  • Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
  • Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
  • Gently press a small amount into your skin and avoid rubbing to keep pores clear.
  • Apply on clean, slightly damp skin to help the product absorb better and control oil.
  • Avoid the sensitive eye area and do a simple patch test before your first use.

People Say

★4.6Overall rating based on 1.0k+ reviews

This moisturizer is praised for its rich texture that plumps, firms, and smooths aging or dry skin without greasiness. Many users report reduced fine lines and improved radiance. Some users experienced product pilling or sensitivity to the fragrance.

Highlights

  • Deeply hydrating Often Mentioned
    • “Keeps my skin moist without the acne.”
    • “Very rich and nourishing.”
    • “Replenishes fragile skin.”
  • Improves texture Often Mentioned
    • “Skin looks smoother, with no discoloration.”
    • “Visibly plumper, firmer, and smoother.”
    • “Skin feels better, smoother and brighter.”
  • Non-greasy formula Sometimes Noted
    • “It's non greasy, absorbs right in.”
    • “Absorbs quickly without any residual grease.”
    • “Not greasy or sticky.”
  • Reduces lines Sometimes Noted
    • “Plumps my skin to reduce the look of fine lines.”
    • “Targets deep wrinkles and creases.”
    • “Saw a reduction in the appearance of fine lines.”
  • Product pilling Sometimes Noted
    • “When I try to apply my liquid makeup over it it rolls up.”
    • “It all pealed away. It looked like a snow storm.”
    • “I do not really experience pilling unless I use too much.”
  • Fragrance sensitivity Rarely Noted
    • “A few reviewers found the fragrance too strong.”
    • “Unfortunately had an allergic reaction.”
    • “Experienced minor irritation.”
  • White cast Rarely Noted
    • “Leaves this white flaky texture on my face.”
    • “Had to really blend so it didn't appear to leave a white cast.”
    • “Doesn't leave a whitecast (after 7 days).”

Sources: lovi.care, perriconemd.com, lovelyskin.com, walmart.com, ipsy.com, nordstrom.com, and more

Questions and answers

How well does Perricone MD Rejuvenating Moisturizer work for oily acne-prone skin?

Perricone MD Rejuvenating Moisturizer works reasonably well for oily acne-prone skin, as glycerin and dimethicone provide good hydration and smoothing without making your skin more oily. While it helps with general hydration and soothing, it lacks specialized ingredients to directly fight breakouts and carries a slight risk of irritation from lactic acid and parfum. To work best for this skin, a moisturizing treatment needs ingredients that clear blemishes and calm redness without clogging pores or adding heavy oils.

Which ingredients make this cream a good fit for oily acne-prone skin?

Glycerin and dimethicone make this cream a good fit for your oily skin because they provide smooth hydration without making you oily, and S-Palmitoylglutathione helps soothe your acne concerns. To be a better fit for oily acne-prone skin, a moisturizing treatment needs ingredients that actively combat blemishes and avoid heavy oils and irritation risks.

Clinical, Cosmetic and Investigational Dermatology, 2017

What does Acyl-Glutathione do for oily acne-prone skin?

Acyl-glutathione helps protect the skin against sun-induced redness and may improve overall tone. This type of product for oily, acne-prone skin needs ingredients that reduce breakouts and soothe irritation while balancing oil.

The Journal of Clinical and Aesthetic Dermatology, 2025Giornale Italiano Di Dermatologia E Venereologia, 2019

What does Vitamin C do for oily acne-prone skin?

Vitamin C helps calm red and irritated skin and may improve the look of post-acne marks when used as part of your routine. For oily and acne-prone skin, this type of product also needs soothing ingredients and lightweight hydrators that keep pores clear without feeling heavy.

European Journal of Pharmaceutics and Biopharmaceutics, 2017Archives of Dermatological Research, 2024

Where does this cream go in a skincare routine for oily acne-prone skin?

This moisturizer goes after your cleanser and hydrating toner in the morning, and after your evening treatment and cleanser at night. Oily acne-prone skin needs a lightweight moisturizer with blemish-clearing ingredients like salicylic acid or niacinamide.

International Journal of Cosmetic Science, 2020

Can I use this cream with retinol, and in what order?

You can use this moisturizing treatment with retinol, applying it after your retinol step to help smooth your skin and keep it hydrated without causing extra oiliness. A product of this type for oily acne-prone skin needs specialized blemish-fighting ingredients alongside light hydrators and soothing agents.

Cutis, 2006

How often should I use this cream?

This cream works well for your oily skin when used twice a day, providing smooth hydration without making you greasy. However, because it lacks specialized ingredients for breakouts, oily acne-prone skin needs products that contain targeted blemish-fighting ingredients and oil-controlling elements to stay clear.

Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021

Can it clog pores, cause breakouts or purging for oily acne-prone skin?

This moisturizer is unlikely to clog pores or cause breakouts on oily skin, as glycerin and dimethicone provide hydration and smoothing without making skin more oily. However, it lacks specialized ingredients for actively fighting blemishes, and an oily acne-prone skin type needs targeted blemish-fighting ingredients and oil-balancing agents to stay clear.

Can I use this cream around the eyes or on my body?

You can use this cream on the body, but it is not specifically designed for the very thin skin around the eyes where the eyelid is thinnest. While glycerin and dimethicone provide hydration, this type of product needs specialized targeted ingredients for delicate areas.

Surgical and Radiologic Anatomy, 2002

Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, citronellol, limonene, and linalool). Cetearyl alcohol is a fatty alcohol, which soften the skin.

What the research says

Why other moisturizers fit oily acne-prone skin better

Ingredients

Water, Ethylhexyl Palmitate, Glycerin, Dimethicone, Cetearyl Alcohol, Glyceryl Stearate, Polysorbate 60, Palmitoyl Glycine, S-Palmitoylglutathione, Tetrahexyldecyl Ascorbate, Peg-100 Stearate, Ribose, Lactic Acid, Linum Usitatissimum Seed Oil, Macadamia Ternifolia Seed Oil, Polyglyceryl-10 Stearate, Ethylhexylglycerin, Salvia Hispanica Seed Oil, Tocopherol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Polyacrylamide, Sodium Acrylates Copolymer, Polysilicone-11, Hydrogenated Polyisobutene, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Parfum, Citronellol, Hydroxycitronellal, Limonene, Linalool

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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